Experimental evidence that pristanic acid disrupts mitochondrial homeostasis in brain of young rats

2011 ◽  
Vol 90 (3) ◽  
pp. 597-605 ◽  
Author(s):  
Estela Natacha Brandt Busanello ◽  
Alexandre Umpierrez Amaral ◽  
Anelise Miotti Tonin ◽  
Mateus Grings ◽  
Alana Pimentel Moura ◽  
...  
Keyword(s):  
Experimental Evidence ◽  
Pristanic Acid ◽  
Mitochondrial Homeostasis ◽  
Young Rats

Pristanic Acid Provokes Lipid, Protein, and DNA Oxidative Damage and Reduces the Antioxidant Defenses in Cerebellum of Young Rats

2014 ◽  
Vol 13 (6) ◽  
pp. 751-759 ◽  
Author(s):  
Estela Natacha Brandt Busanello ◽  
Vannessa Gonçalves Araujo Lobato ◽  
Ângela Zanatta ◽  
Clarissa Günther Borges ◽  
Anelise Miotti Tonin ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Antioxidant Defenses ◽  
Pristanic Acid ◽  
Dna Oxidative Damage ◽  
Young Rats

Disruption of oxidative phosphorylation and synaptic Na+, K+-ATPase activity by pristanic acid in cerebellum of young rats

Life Sciences ◽  
2014 ◽  
Vol 94 (1) ◽  
pp. 67-73
Author(s):  
Estela Natacha Brandt Busanello ◽  
Vannessa Gonçalves Araujo Lobato ◽  
Ângela Zanatta ◽  
Carolina Maso Viegas ◽  
César Augusto João Ribeiro ◽  
...  
Keyword(s):  
Oxidative Phosphorylation ◽  
Atpase Activity ◽  
Pristanic Acid ◽  
Young Rats

Experimental Evidence that Methylmalonic Acid Provokes Oxidative Damage and Compromises Antioxidant Defenses in Nerve Terminal and Striatum of Young Rats

2011 ◽  
Vol 31 (5) ◽  
pp. 775-785 ◽  
Author(s):  
Carolina Gonçalves Fernandes ◽  
Clarissa Günther Borges ◽  
Bianca Seminotti ◽  
Alexandre Umpierrez Amaral ◽  
Lisiane Aurélio Knebel ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Experimental Evidence ◽  
Nerve Terminal ◽  
Methylmalonic Acid ◽  
Antioxidant Defenses ◽  
Young Rats

Neurochemical Evidence that Pristanic Acid Impairs Energy Production and Inhibits Synaptic Na+, K+-ATPase Activity in Brain of Young Rats

2011 ◽  
Vol 36 (6) ◽  
pp. 1101-1107 ◽  
Author(s):  
Estela Natacha Brandt Busanello ◽  
Carolina Maso Viegas ◽  
Anelise Miotti Tonin ◽  
Mateus Grings ◽  
Alana Pimentel Moura ◽  
...  
Keyword(s):  
Atpase Activity ◽  
Energy Production ◽  
Pristanic Acid ◽  
Young Rats

Phytanic acid disturbs mitochondrial homeostasis in heart of young rats: a possible pathomechanism of cardiomyopathy in Refsum disease

2012 ◽  
Vol 366 (1-2) ◽  
pp. 335-343 ◽  
Author(s):  
Mateus Grings ◽  
Anelise Miotti Tonin ◽  
Lisiane Aurélio Knebel ◽  
Ângela Zanatta ◽  
Alana Pimentel Moura ◽  
...  
Keyword(s):  
Phytanic Acid ◽  
Refsum Disease ◽  
Mitochondrial Homeostasis ◽  
Young Rats

Disruption of Mitochondrial Homeostasis by Phytanic Acid in Cerebellum of Young Rats

2012 ◽  
Vol 12 (3) ◽  
pp. 362-369 ◽  
Author(s):  
Estela Natacha Brandt Busanello ◽  
Alexandre Umpierrez Amaral ◽  
Anelise Miotti Tonin ◽  
Ângela Zanatta ◽  
Carolina Maso Viegas ◽  
...  
Keyword(s):  
Phytanic Acid ◽  
Mitochondrial Homeostasis ◽  
Young Rats

scholarly journals Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats

2009 ◽  
Vol 1291 ◽  
pp. 102-112 ◽  
Author(s):  
Carolina Maso Viegas ◽  
Ângela Zanatta ◽  
Lisiane Aurélio Knebel ◽  
Patrícia Fernanda Schuck ◽  
Anelise Miotti Tonin ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Experimental Evidence ◽  
Young Rats

scholarly journals Pristanic acid promotes oxidative stress in brain cortex of young rats: A possible pathophysiological mechanism for brain damage in peroxisomal disorders

2011 ◽  
Vol 1382 ◽  
pp. 259-265 ◽  
Author(s):  
Guilhian Leipnitz ◽  
Alexandre Umpierrez Amaral ◽  
Carolina Gonçalves Fernandes ◽  
Bianca Seminotti ◽  
Ângela Zanatta ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Brain Damage ◽  
Brain Cortex ◽  
Pathophysiological Mechanism ◽  
Pristanic Acid ◽  
Peroxisomal Disorders ◽  
Young Rats

How do memory modules differentially contribute to familiarity and recollection?

2019 ◽  
Vol 42 ◽  
Author(s):  
Olya Hakobyan ◽  
Sen Cheng
Keyword(s):  
Recognition Memory ◽  
Experimental Evidence ◽  
Subjective Experience ◽  
Target Article ◽  
Memory Modules ◽  
Familiarity And Recollection ◽  
Memory Contents

Abstract We fully support dissociating the subjective experience from the memory contents in recognition memory, as Bastin et al. posit in the target article. However, having two generic memory modules with qualitatively different functions is not mandatory and is in fact inconsistent with experimental evidence. We propose that quantitative differences in the properties of the memory modules can account for the apparent dissociation of recollection and familiarity along anatomical lines.

Redox Reactions in Lipid Membranes as a Model for Primordial Energy-Conserving Systems

1997 ◽  
Vol 161 ◽  
pp. 437-442
Author(s):  
Salvatore Di Bernardo ◽  
Romana Fato ◽  
Giorgio Lenaz
Keyword(s):  
Experimental Evidence ◽  
Lipid Membranes ◽  
Energy Supply ◽  
Redox Reactions ◽  
Living Systems ◽  
Asymmetric Distribution ◽  
Conservation Of Energy ◽  
Asymmetrical Distribution ◽  
Energy Conserving ◽  
Living Organisms

AbstractOne of the peculiar aspects of living systems is the production and conservation of energy. This aspect is provided by specialized organelles, such as the mitochondria and chloroplasts, in developed living organisms. In primordial systems lacking specialized enzymatic complexes the energy supply was probably bound to the generation and maintenance of an asymmetric distribution of charged molecules in compartmentalized systems. On the basis of experimental evidence, we suggest that lipophilic quinones were involved in the generation of this asymmetrical distribution of charges through vectorial redox reactions across lipid membranes.

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