Shear strain and inflammation‐induced fixed charge density loss in the knee joint cartilage following ACL injury and reconstruction: a computational study

2021 ◽  
Author(s):  
Gustavo A. Orozco ◽  
Atte S.A. Eskelinen ◽  
Joonas P. Kosonen ◽  
Matthew S. Tanaka ◽  
Mingrui Yang ◽  
...  
Keyword(s):  
Knee Joint ◽  
Charge Density ◽  
Shear Strain ◽  
Computational Study ◽  
Acl Injury ◽  
Fixed Charge ◽  
Joint Cartilage ◽  
Fixed Charge Density

Spatial variation of fixed charge density in knee joint cartilage from sodium MRI – Implication on knee joint mechanics under static loading

2016 ◽  
Vol 49 (14) ◽  
pp. 3387-3396 ◽  
Author(s):  
Lasse P. Räsänen ◽  
Petri Tanska ◽  
Mika E. Mononen ◽  
Eveliina Lammentausta ◽  
Štefan Zbýň ◽  
...  
Keyword(s):  
Knee Joint ◽  
Charge Density ◽  
Spatial Variation ◽  
Static Loading ◽  
Fixed Charge ◽  
Joint Mechanics ◽  
Joint Cartilage ◽  
Fixed Charge Density ◽  
Sodium Mri ◽  
Knee Joint Mechanics

The effect of fixed charge density and cartilage swelling on mechanics of knee joint cartilage during simulated gait

2017 ◽  
Vol 61 ◽  
pp. 34-44 ◽  
Author(s):  
Lasse P. Räsänen ◽  
Petri Tanska ◽  
Štefan Zbýň ◽  
Corrinus C. van Donkelaar ◽  
Siegfried Trattnig ◽  
...  
Keyword(s):  
Knee Joint ◽  
Charge Density ◽  
Fixed Charge ◽  
Joint Cartilage ◽  
Fixed Charge Density ◽  
And Cartilage

scholarly journals 23Na MRI accurately measures fixed charge density in articular cartilage

2002 ◽  
Vol 47 (2) ◽  
pp. 284-291 ◽  
Author(s):  
Erik M. Shapiro ◽  
Arijitt Borthakur ◽  
Alexander Gougoutas ◽  
Ravinder Reddy
Keyword(s):  
Articular Cartilage ◽  
Charge Density ◽  
Fixed Charge ◽  
Fixed Charge Density ◽  
23Na Mri

Fixed charge density and cartilage biomechanics

2002 ◽  
pp. 387-395
Author(s):  
Robert J. Wilkins ◽  
Bethan Hopewell ◽  
Jill P. G. Urban
Keyword(s):  
Charge Density ◽  
Fixed Charge ◽  
Fixed Charge Density ◽  
Cartilage Biomechanics ◽  
And Cartilage

Electrophysiology of renal capillary membranes: gel concept applied and Starling model challenged

1988 ◽  
Vol 254 (3) ◽  
pp. F364-F373 ◽  
Author(s):  
M. Wolgast ◽  
G. Ojteg
Keyword(s):  
Charge Density ◽  
Electrical Potential ◽  
Potential Gradient ◽  
Swelling Pressure ◽  
Porous Membrane ◽  
Fixed Charge ◽  
Fixed Charge Density ◽  
Capillary Membranes ◽  
External Forces ◽  
Gel Membranes

In the classical Starling model the hydrostatic pressure in the pores is generally lower than that in capillary plasma, a phenomenon that necessitates the assumption of a rigid porous membrane. In flexible gel membranes, the capillary pressure is suggested to be balanced by a gel swelling pressure generated by negative fixed charges. Regarding the fluid transfer, the transmembranous electrical potential gradient will generate a net driving electroosmotic force. This force will be numerically similar to the net driving Starling force in small pores, but distinctly different in large pores. From previous data on the hydrostatic and colloid osmotic forces, the fixed charge density at the two interfaces of 1) the glomerular and 2) the peritubular capillary membrane were calculated and used to predict the flux of a series of charged protein probes. The close fit to the experimental data in both the capillary beds is in line with the gel concept presented. The gel concept (but hardly a rigid membrane) explains the ability of capillary membranes to alter their permeability in response to external forces. Gel membranes can furthermore be predicted to have a self-rinsing ability, as entrapped proteins will increase the local fixed charge density, leading to fluid entry into the region between the particle and the pore rim, which by consequent widening of the channel will facilitate extrusion of trapped proteins.

Dependence of Electrical Conductivity on Fixed Charge Density in Articular Cartilage

1983 ◽  
Vol &NA; (177) ◽  
pp. 283???288 ◽  
Author(s):  
ISAO HASEGAWA ◽  
SHINYA KURIKI ◽  
SHIGEO MATSUNO ◽  
GORO MATSUMOTO
Keyword(s):  
Electrical Conductivity ◽  
Articular Cartilage ◽  
Charge Density ◽  
Fixed Charge ◽  
Fixed Charge Density
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