Ethanol Lock Therapy for the Prevention of Nontunneled Catheter‐Related Bloodstream Infection in Pediatric Patients

2019 ◽  
Vol 43 (8) ◽  
pp. 1044-1052 ◽  
Author(s):  
Bellisa Caldas Lopes ◽  
Paulo Sérgio Gomes Nogueira Borges ◽  
Rodrigo Melo Gallindo ◽  
Thuanne Beatriz Silva Tenório ◽  
Lara Barreto Machado ◽  
...  
Keyword(s):  
Bloodstream Infection ◽  
Pediatric Patients ◽  
Lock Therapy ◽  
Ethanol Lock ◽  
Catheter Related Bloodstream Infection

Hospital Readmissions for Catheter-Related Bloodstream Infection and Use of Ethanol Lock Therapy

2012 ◽  
Vol 37 (1) ◽  
pp. 81-84 ◽  
Author(s):  
Mandy L. Corrigan ◽  
Cassandra Pogatschnik ◽  
Denise Konrad ◽  
Donald F. Kirby
Keyword(s):  
Bloodstream Infection ◽  
Hospital Readmissions ◽  
Lock Therapy ◽  
Ethanol Lock ◽  
Catheter Related Bloodstream Infection

Antibiotic lock therapy for salvage of tunneled central venous catheters with catheter colonization and catheter-related bloodstream infection

2018 ◽  
Vol 21 (1) ◽  
pp. e13017 ◽  
Author(s):  
Saurabh Zanwar ◽  
Punit Jain ◽  
Anant Gokarn ◽  
Santhosh Kumar Devadas ◽  
Sachin Punatar ◽  
...  
Keyword(s):  
Bloodstream Infection ◽  
Central Venous Catheters ◽  
Catheter Colonization ◽  
Central Venous ◽  
Lock Therapy ◽  
Antibiotic Lock ◽  
Catheter Related Bloodstream Infection

Evaluation of Ethanol Lock Therapy in Pediatric Patients on Long-Term Parenteral Nutrition

2012 ◽  
Vol 28 (2) ◽  
pp. 226-231 ◽  
Author(s):  
Kevin P. Pieroni ◽  
Colleen Nespor ◽  
Marisa Ng ◽  
Manuel Garcia ◽  
Melissa Hurwitz ◽  
...  
Keyword(s):  
Parenteral Nutrition ◽  
Pediatric Patients ◽  
Lock Therapy ◽  
Ethanol Lock

scholarly journals Vancomycin-lock therapy for prevention of catheter-related bloodstream infection in very low body weight infants

2020 ◽  
Author(s):  
Hong Liang ◽  
Lian Zhang ◽  
Xiaoping Guo ◽  
Li Sun
Keyword(s):  
Body Weight ◽  
Bloodstream Infection ◽  
Preterm Infants ◽  
Exposure Time ◽  
Pathogenic Bacteria ◽  
Control Group ◽  
Antibiotic Exposure ◽  
Blood Concentrations ◽  
Lock Therapy ◽  
Catheter Related Bloodstream Infection

Abstract Background: This study was to evaluate the effectiveness and safety of vancomycin- lock therapy for the prevention of catheter-related bloodstream infection (CRBSI) in very low body weight (VLBW) preterm infant patients.Methods: One hundred and thirty-seven cases of VLBW preterm infants who retained peripherally inserted central catheters (PICCs) were retrospectively reviewed, including 68 treating with heparin plus vancomycin (vancomycin-lock group) and 69 with heparin only (control group). The incidence of CRBSI, related pathogenic bacteria, adverse events during the treatment, complications, antibiotic exposure, PICC usage time, hospital stay, etc. were compared between the above two groups.Results: The incidence rate of CRBSI in the vancomycin-lock group (4.4%, 3/68) was significantly less than in the control group (21.7%, 15/69, p=0.004). Total antibiotic exposure time during the whole observation period was significantly shorter in the group than in the control group (11.2±10.0 vs 23.6±16.1 d; p<0.001). No hypoglycemia occurred during the locking, and the blood concentrations of vancomycin were not detectable.Conclusions: Vancomycin-lock may effectively prevent CRBSI in Chinese VLBW preterm infants, prolong the usage time of PICC line, and reduce the exposure time of antibiotics, without causing obvious side complications.

Successful tigecycline lock therapy in a Lactobacillus rhamnosus catheter-related bloodstream infection

Infection ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 331-334 ◽  
Author(s):  
F. Bartalesi ◽  
S. Veloci ◽  
F. Baragli ◽  
E. Mantengoli ◽  
S. Guidi ◽  
...  
Keyword(s):  
Bloodstream Infection ◽  
Lactobacillus Rhamnosus ◽  
Lock Therapy ◽  
Catheter Related Bloodstream Infection

Efficacy in the Reduction of Central Line-Associated Bloodstream Infection in a Patient With Intestinal Failure: An Ethanol Lock Pediatric Case Study

2014 ◽  
Vol 19 (4) ◽  
pp. 217-220 ◽  
Author(s):  
Stephanie Pitts ◽  
Dale Bergamo ◽  
Carlos Cartaya ◽  
Beth Gore
Keyword(s):  
Bloodstream Infection ◽  
Intestinal Failure ◽  
Bloodstream Infections ◽  
Central Line ◽  
Central Venous ◽  
Pediatric Case ◽  
Time Period ◽  
Lock Therapy ◽  
Ethanol Lock

Abstract Intestinal failure and the subsequent reliance on parentral nutrition through central venous catheters increases the likelihood of a central line-associated bloodstream infection. Antimicrobial lock solutions such as ethanol lock therapy are providing promising evidence of the ability to reduce central line-associated bloodstream infection. This case study reviews the use of ethanol lock therapy for a pediatric patient who experienced 0 central line-associated bloodstream infections during the 2-year time period covered by this report.

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