Study of Raman spectrum of uranium using a surface-enhanced Raman scattering technique

2011 ◽  
Vol 42 (5) ◽  
pp. 885-887 ◽  
Author(s):  
T. R. Ravindran ◽  
A. K. Arora
Nanomedicine ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. 913-926 ◽  
Author(s):  
Hui Chen ◽  
Caixia Luo ◽  
Moyu Yang ◽  
Junying Li ◽  
Pei Ma ◽  
...  

Aim: Exosomes, known as novel biocompatible vesicles, have attracted much interest. This makes it urgent to observe exosomes at the visually cellular or subcellular levels. Methods: Herein, we constructed a new kind of exosome/metal nanohybrid and employed a surface-enhanced Raman scattering technique to study the intracellular behaviors of hybrid exosomes. Results: Experimental results revealed that hybrid exosomes were internalized mainly through clathrin-mediated endocytosis and thereafter transported to lysosomes. The metal nanoparticles in the hybrid were demonstrated to have little effect on exosomal characteristics while serving as surface-enhanced Raman scattering generators. Conclusion: This study is significant for removing the barrier in designing programmable exosome/metal nanohybrids, which will greatly improve the utility of exosomal nanohybrids for therapeutics, such as multifunctional drug-delivery systems.


2015 ◽  
Vol 17 (41) ◽  
pp. 27258-27263 ◽  
Author(s):  
Mykhaylo M. Dvoynenko ◽  
Juen-Kai Wang

A continuum background is always coincident with the Raman spectrum enhanced by metallic nanostructures and still remains elusive.


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