Narrow band imaging in head and neck unknown primary carcinoma: A systematic review and meta‐analysis

2019 ◽  
Vol 130 (7) ◽  
pp. 1692-1700 ◽  
Author(s):  
Pasquale Di Maio ◽  
Oreste Iocca ◽  
Armando Virgilio ◽  
Marco Giudice ◽  
Raul Pellini ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Meta Analysis ◽  
Primary Carcinoma ◽  
Unknown Primary ◽  
Unknown Primary Carcinoma

scholarly journals Surveillance in inflammatory bowel disease: is chromoendoscopy the only way to go? A systematic review and meta-analysis of randomized clinical trials

2020 ◽  
Vol 08 (05) ◽  
pp. E578-E590
Author(s):  
Ricardo Hannum Resende ◽  
Igor Braga Ribeiro ◽  
Diogo Turiani Hourneaux de Moura ◽  
Facundo Galetti ◽  
Rodrigo Silva de Paula Rocha ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Meta Analysis ◽  
Mean Difference ◽  
Procedure Time ◽  
High Definition ◽  
Number Of Patients

Abstract Background and study aims Ulcerative colitis (UC) and Crohn’s disease (CD) have higher risk of colorectal cancer (CRC). Guidelines recommend dysplasia surveillance with dye-spraying chromoendoscopy (DCE). The aim of this systematic review and meta-analysis was to review all randomized clinical trials (RCTs) available and compare the efficacy of different endoscopic methods of surveillance for dysplasia in patients with UC and CD. Methods Databases searched were Medline, EMBASE, Cochrane and SCIELO/LILACS. It was estimated the risk difference (RD) for dichotomous outcomes (number of patients diagnosed with one or more dysplastic lesions, total number of dysplastic lesions diagnosed and number of dysplastic lesions detected by targeted biopsies) and mean difference for continuous outcomes (procedure time). Results This study included 17 RCTs totaling 2,457 patients. There was superiority of DCE when compared to standard-definiton white light endoscopy (SD-WLE). When compared with high-definition (HD) WLE, no difference was observed in all outcomes (number of patients with dysplasia (RD 0.06; 95 % CI [–0.01, 0.13])). Comparing other techniques, no difference was observed between DCE and virtual chromoendoscopy (VCE – including narrow-band imaging [NBI], i-SCAN and flexible spectral imaging color enhancement), in all outcomes except procedure time (mean difference, 6.33 min; 95 % CI, 1.29, 11.33). DCE required a significantly longer procedure time compared with WLE (mean difference, 7.81 min; 95 % CI, 2.76, 12.86). Conclusions We found that dye-spraying chromoendoscopy detected more patients and dysplastic lesions than SD-WLE. Although no difference was observed between DCE and HD-WLE or narrow-band imaging, the main outcomes favored numerically dye-spraying chromoendoscopy, except procedure time. Regarding i-SCAN, FICE and auto-fluorescence imaging, there is still not enough evidence to support or not their recommendation.

scholarly journals Performance of Narrow Band Imaging (NBI) and Photodynamic Diagnosis (PDD) Fluorescence Imaging Compared to White Light Cystoscopy (WLC) in Detecting Non-Muscle Invasive Bladder Cancer: A Systematic Review and Lesion-Level Diagnostic Meta-Analysis

Cancers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 4378
Author(s):  
Giorgio I. Russo ◽  
Tamir N. Sholklapper ◽  
Andrea Cocci ◽  
Giuseppe Broggi ◽  
Rosario Caltabiano ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bladder Cancer ◽  
White Light ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Meta Analysis ◽  
Photodynamic Diagnosis ◽  
Muscle Invasive Bladder Cancer ◽  
White Light Cystoscopy ◽  
Muscle Invasive

Despite early detection and regular surveillance of non-muscle invasive bladder cancer (NMIBC), recurrence and progression rates remain exceedingly high for this highly prevalent malignancy. Limited visualization of malignant lesions with standard cystoscopy and associated false-negative biopsy rates have been the driving force for investigating alternative and adjunctive technologies for improved cystoscopy. The aim of our systematic review and meta-analysis was to compare the sensitivity, specificity, and oncologic outcomes of photodynamic diagnosis (PDD) fluorescence, narrow band imaging (NBI), and conventional white light cystoscopy (WLC) in detecting NMIBC. Out of 1,087 studies reviewed, 17 prospective non-randomized and randomized controlled trials met inclusion criteria for the study. We demonstrated that tumor resection with either PDD and NBI exhibited lower recurrence rates and greater diagnostic sensitivity compared to WLC alone. NBI demonstrated superior disease sensitivity and specificity as compared to WLC and an overall greater hierarchical summary receiver operative characteristic. Our findings are consistent with emerging guidelines and underscore the value of integrating these enhanced technologies as a part of the standard care for patients with suspected or confirmed NMIBC.

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