scholarly journals Bone marrow stromal cells protect acute myeloid leukemia cells from anti‐CD44 therapy partly through regulating PI3K/Akt–p27 Kip1 axis

2014 ◽  
Vol 54 (12) ◽  
pp. 1678-1685 ◽  
Author(s):  
Ping Chen ◽  
Huifang Huang ◽  
Juanying Wu ◽  
Rong Lu ◽  
Yong Wu ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Myeloid Leukemia ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Myeloid Leukemia ◽  
Marrow Stromal Cells ◽  
Leukemia Cells ◽  
Acute Myeloid Leukemia Cells ◽  
P27 Kip1 ◽  
Acute Myeloid

c-Myc plays part in drug resistance mediated by bone marrow stromal cells in acute myeloid leukemia

2015 ◽  
Vol 39 (1) ◽  
pp. 92-99 ◽  
Author(s):  
Bing Xia ◽  
Chen Tian ◽  
Shanqi Guo ◽  
Le Zhang ◽  
Dandan Zhao ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Drug Resistance ◽  
Acute Myeloid Leukemia ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Myeloid Leukemia ◽  
Marrow Stromal Cells ◽  
Acute Myeloid

scholarly journals Mitochondria on the move: BMSCs fuel AML energy

Blood ◽  
2017 ◽  
Vol 130 (14) ◽  
pp. 1603-1604
Author(s):  
Rosa Lapalombella
Keyword(s):  
Bone Marrow ◽  
Acute Myeloid Leukemia ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Myeloid Leukemia ◽  
Therapeutic Strategy ◽  
Marrow Stromal Cells ◽  
Tunneling Nanotubes ◽  
Acute Myeloid ◽  
Novel Therapeutic

In this issue of Blood, Marlein et al1 identify a tumor-specific NOX2-dependent transfer of mitochondria from bone marrow stromal cells (BMSCs) to acute myeloid leukemia (AML) cells via AML-derived tunneling nanotubes (see figure), supporting inhibition of NOX2 as a novel therapeutic strategy in AML.

Chemotherapeutic treatment of bone marrow stromal cells strongly affects their protective effect on acute myeloid leukemia cell survival

2008 ◽  
Vol 49 (1) ◽  
pp. 134-148 ◽  
Author(s):  
Bijan Moshaver ◽  
Marjolein A. van der Pol ◽  
August H. Westra ◽  
Gert J. Ossenkoppele ◽  
Sonja Zweegman ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Myeloid Leukemia ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Myeloid Leukemia ◽  
Leukemia Cell ◽  
Marrow Stromal Cells ◽  
Chemotherapeutic Treatment ◽  
Acute Myeloid ◽  
Myeloid Leukemia Cell
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