scholarly journals Magnetic Resonance‐Guided Focused Ultrasound Thalamotomy for Focal Hand Dystonia: A Pilot Study

2021 ◽  
Author(s):  
Shiro Horisawa ◽  
Toshio Yamaguchi ◽  
Keiichi Abe ◽  
Hiroki Hori ◽  
Atsushi Fukui ◽  
...  
Keyword(s):  
Pilot Study ◽  
Magnetic Resonance ◽  
Focused Ultrasound ◽  
Focal Hand Dystonia ◽  
Hand Dystonia

Assessment of the effects of Kinesiotaping on musical motor performance in musicians suffering from focal hand dystonia: a pilot study

2019 ◽  
Vol 33 (10) ◽  
pp. 1636-1648 ◽  
Author(s):  
Riccardo Bravi ◽  
Christos I Ioannou ◽  
Diego Minciacchi ◽  
Eckart Altenmüller
Keyword(s):  
Pilot Study ◽  
Repeated Measures ◽  
Motor Performance ◽  
Fine Motor ◽  
Electromyographic Activity ◽  
Focal Hand Dystonia ◽  
General Performance ◽  
Antagonist Muscles ◽  
Hand Dystonia ◽  
Analogue Scales

Objective:The aim of this study was to explore the immediate and short-term effects of a Correction Kinesiotaping intervention on fine motor control in musicians with focal hand dystonia.Design:A single-blinded, single-arm repeated measures, pilot study.Setting:Medical outpatient clinic.Subjects:Seven musicians diagnosed with focal hand dystonia.Interventions:Musicians performed musical exercises under the following conditions: without Kinesiotape (baseline), during a Correction Kinesiotaping intervention and immediately after tape removal (block 1) and during a Sham Kinesiotaping intervention and immediately after tape removal (block 2). Blocks were randomly presented across participants. A tailored Correction Kinesiotaping intervention on affected fingers was provided based on the dystonic pattern that each patient manifested while playing.Main measures:Motor performance was video-documented and independent experts blindly assessed the general performance and fingers’ posture on visual analogue scales. Also, musicians’ self-reports of the musical abilities were evaluated. Finally, electromyographic activity and coactivation index of wrist antagonist muscles were analyzed.Results:No significant differences in effects between Correction Kinesiotaping and Sham Kinesiotaping were reported by the experts, either for general performance ( P > 0.05) or for fingers’ posture ( P > 0.05); any subtle benefits observed during Correction Kinesiotaping were lost after the tape was removed. Musicians estimated that Correction Kinesiotaping was ineffective in improving their musical abilities. Also, no significant changes with respect to the coactivation index ( P > 0.05) were found among the conditions.Conclusion:Correction Kinesiotaping intervention may not be useful to reduce dystonic patterns, nor to improve playing ability, in musicians with focal hand dystonia.

Proton Magnetic Resonance Spectroscopy of the Basal Ganglia in Idiopathic Focal Hand Dystonia

1998 ◽  
Vol 11 (2_suppl) ◽  
pp. 10-12
Author(s):  
M. Warmuth-Metz ◽  
M. Naumann ◽  
C. Hillerer ◽  
K. Reiners ◽  
T. Pabst ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Proton Magnetic Resonance ◽  
Proton Magnetic Resonance Spectroscopy ◽  
Resonance Spectroscopy ◽  
Focal Hand Dystonia ◽  
Hand Dystonia

scholarly journals Magnetic Resonance–Guided High-Intensity-Focused Ultrasound for Palliation of Painful Skeletal Metastases: A Pilot Study

2016 ◽  
Vol 16 (5) ◽  
pp. 570-576 ◽  
Author(s):  
Michael Chan ◽  
Kristopher Dennis ◽  
Yuexi Huang ◽  
Charles Mougenot ◽  
Edward Chow ◽  
...  
Keyword(s):  
Pilot Study ◽  
Magnetic Resonance ◽  
Bone Metastases ◽  
Focused Ultrasound ◽  
Metastatic Cancer ◽  
High Intensity Focused Ultrasound ◽  
Clinical Indication ◽  
Skeletal Metastases ◽  
Pain Response ◽  
Painful Bone Metastases

Background: Bone is one of the most common sites of metastases, with bone metastases-related pain representing a significant source of morbidity among patients with cancer. Magnetic resonance–guided focused ultrasound is a noninvasive, outpatient modality with the potential for treating painful bone metastases. The aim of this study is to report our initial experience with magnetic resonance–guided focused ultrasound in the treatment of bone metastases and our preliminary analysis of urinary cytokine levels after therapy. Methods: This was a single-center pilot study of 10 patients with metastatic cancer to investigate the feasibility of magnetic resonance–guided focused ultrasound for primary pain control in device-accessible skeletal metastases. Treatments were performed on a clinical magnetic resonance–guided focused ultrasound system using a volumetric ablation technique. Primary efficacy was assessed using Brief Pain Inventory scores and morphine equivalent daily dose intake at 3 time points: before, day 14, and day 30 after the magnetic resonance–guided focused ultrasound treatment. Urine cytokines were measured 3 days before treatment and 2 days after the treatment. Results: Of the 10 patients, 8 were followed up 14 days and 6 were followed up 30 days after the treatment. At day 14, 3 patients (37.5%) exhibited partial pain response and 4 patients (50%) exhibited an indeterminate response, and at day 30 after the treatment, 5 patients (83%) exhibited partial pain response. No treatment-related adverse events were recorded. Of the urine cytokines measured, only Transforming growth factor alpha (TGFα) demonstrated an overall decrease, with a trend toward statistical significance ( P = .078). Conclusion: Our study corroborates magnetic resonance–guided focused ultrasound as a feasible and safe modality as a primary, palliative treatment for painful bone metastases and contributes to the limited body of literature using magnetic resonance–guided focused ultrasound for this clinical indication.

Transcranial Direct Current Stimulation Improves Neurorehabilitation of Task-Specific Dystonia: A Pilot Study

2014 ◽  
Vol 29 (1) ◽  
pp. 16-18 ◽  
Author(s):  
Jaume Rosset-Llobet ◽  
Sílvia Fàbregas-Molas ◽  
Álvaro Pascual-Leone
Keyword(s):  
Clinical Trial ◽  
Pilot Study ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation ◽  
Focal Hand Dystonia ◽  
Parallel Group ◽  
Sensory Motor ◽  
Hand Dystonia ◽  
Proof Of Principle

Sensory-motor retuning (SMR) can help the symptoms of task-specific focal hand dystonia. However, effects vary across patients and take many sessions. Here, we present proof of principle evidence that transcranial direct current stimulation (tDCS) can enhance these effects. We compared the effects of a combined tDCS-SMR protocol (n=4 patients) with the efficacy of SMR alone (n=30 patients). All 4 patients treated with the combined protocol showed greater improvement than those undergoing SMR alone. Results encourage a larger, parallel-group clinical trial with sham tDCS control.

Finger Movement Discrimination in Focal Hand Dystonia: Case Study of a Cellist

2005 ◽  
Vol 20 (2) ◽  
pp. 77-81
Author(s):  
Bronwen J Ackermann ◽  
Roger Adams
Keyword(s):  
Pilot Study ◽  
Rating Scale ◽  
Rehabilitation Program ◽  
Finger Movement ◽  
Focal Hand Dystonia ◽  
Hand Dystonia ◽  
Intensive Physiotherapy ◽  
Positive Results ◽  
Movement Discrimination

Focal hand dystonia in musicians has received increasing attention in recent years due to the debilitating and career-threatening nature of this condition. In cellists, focal hand dystonia is reported only infrequently in the existing literature, as compared to the rate in other instrumentalists, such as pianists and violinists. Although relatively less common, it has similarly devastating effects for those with this disorder. In the pilot study presented here, a 47-year-old male professional cellist experiencing left focal hand dystonia underwent pretests and posttests when he attended a 10-day period of intensive sensorimotor retraining. To monitor the effects of treatment, a pseudo-cello was designed that used the principles of psychophysical methodology to test active finger movement discrimination. This test was designed to evaluate whether this cellist could perceive the relative position of his left fingers in as task-specific a manner as possible. The pseudo-cello results showed a reduced ability to discriminate the height and tension of a string in the fingers most affected by the dystonia. Following the 10-day period of intensive physiotherapy, discrimination of finger movements had improved in the fingers that had been worked on with the rehabilitation program, and this corresponded with an improvement in the dystonia rating scale. The positive results obtained here suggest that this form of testing in focal hand dystonia warrants further research.

scholarly journals In vivo neurochemistry of primary focal hand dystonia: A magnetic resonance spectroscopic neurometabolite profiling study at 3T

2010 ◽  
Vol 25 (16) ◽  
pp. 2800-2808 ◽  
Author(s):  
Priyantha Herath ◽  
Cecile Gallea ◽  
Jan Willem van der Veen ◽  
Silvina G. Horovitz ◽  
Mark Hallett
Keyword(s):  
Magnetic Resonance ◽  
Focal Hand Dystonia ◽  
Hand Dystonia

1 H Magnetic resonance spectroscopy of the lentiform nucleus in primary focal hand dystonia

1998 ◽  
Vol 13 (6) ◽  
pp. 929-933 ◽  
Author(s):  
Markus Naumann ◽  
Monika Warmuth‐Metz ◽  
Claudia Hillerer ◽  
László Solymosi ◽  
Karlheinz Reiners
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Resonance Spectroscopy ◽  
Lentiform Nucleus ◽  
Focal Hand Dystonia ◽  
Hand Dystonia
Sign in / Sign up

Export Citation Format

Share Document