scholarly journals Estimating lung, breast, and effective dose from low-dose lung cancer screening CT exams with tube current modulation across a range of patient sizes

2018 ◽  
Vol 45 (10) ◽  
pp. 4667-4682 ◽  
Author(s):  
Anthony J. Hardy ◽  
Maryam Bostani ◽  
Kyle McMillan ◽  
Maria Zankl ◽  
Cynthia McCollough ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Effective Dose ◽  
Low Dose ◽  
Lung Cancer Screening ◽  
Tube Current Modulation ◽  
Current Modulation ◽  
Tube Current

TU-H-207A-08: Estimating Radiation Dose From Low-Dose Lung Cancer Screening CT Exams Using Tube Current Modulation

2016 ◽  
Vol 43 (6Part37) ◽  
pp. 3773-3773 ◽  
Author(s):  
A Hardy ◽  
M Bostani ◽  
K McMillan ◽  
M Zankl ◽  
C Cagnon ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Radiation Dose ◽  
Low Dose ◽  
Lung Cancer Screening ◽  
Tube Current Modulation ◽  
Current Modulation ◽  
Tube Current

OPTIMAL TUBE CURRENT FOR LUNG CANCER SCREENING WITH LOW-DOSE SPIRAL CT

2000 ◽  
Vol 41 (4) ◽  
pp. 352-356
Author(s):  
K. Oguchi ◽  
S. Sone ◽  
K. Kiyono ◽  
S. Takashima ◽  
Y. Maruyama ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Low Dose ◽  
Lung Cancer Screening ◽  
Spiral Ct ◽  
Tube Current

Comparison of ultra-low dose chest CT scanning protocols for the detection of pulmonary nodules: a phantom study

2019 ◽  
Vol 105 (5) ◽  
pp. 394-403 ◽  
Author(s):  
Gianluca Milanese ◽  
Mario Silva ◽  
Thomas Frauenfelder ◽  
Matthias Eberhard ◽  
Federica Sabia ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Low Dose ◽  
Pulmonary Nodules ◽  
Lung Cancer Screening ◽  
Ct Scanning ◽  
Tube Current Modulation ◽  
Ct Scanner ◽  
Current Modulation ◽  
Tube Current ◽  
Dual Source

Purpose:To test ultra-low-dose computed tomography (ULDCT) scanning protocols for the detection of pulmonary nodules (PN).Methods:A chest phantom containing 19 solid and 11 subsolid PNs was scanned on a third-generation dual-source computed tomography (CT) scanner. Five ULDCT scans (Sn100kVp and 120, 70, 50, 30, and 20 reference mAs, using tube current modulation), reconstructed with iterative reconstruction (IR) algorithm at strength levels 2, 3, 4, and 5, were compared with standard CT (120kVp, 150 reference mAs, using tube current modulation). PNs were subjectively assessed according to a 4-point scale: 0, nondetectable nodule; 1, detectable nodule, very unlikely to be correctly measured; 2, detectable nodule, likely to be correctly measured; 3, PN quality equal to standard of reference. PN scores were analysed according to the Lung Imaging Reporting and Data System (Lung-RADS), simulating detection of nodules at baseline and incidence screening round.Results:For the baseline round, there were 17 Lung-RADS 2, 4 Lung-RADS 3, 8 Lung-RADS 4A, and 1 Lung-RADS 4B PNs. They were detectable in any ULDCT protocol, with the exception of 1 nondetectable part-solid nodule in 1 scanning protocol (120 reference mAs; IR strength: 3). For the incidence round, there were 4 Lung-RADS 2, 14 Lung-RADS 3, 2 Lung-RADS 4A, and 10 Lung-RADS 4B PNs. Ten were nondetectable in at least one ULDCT dataset; however, they were at least detectable in ULDCT with 70 reference mAs (IR strength: 4 and 5).Conclusions:ULDCT scanning protocols allowing the detection of PNs can be proposed for the purpose of lung cancer screening.

scholarly journals Repeatability of small lung nodule measurement in low-dose lung screening: a phantom study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yu Du ◽  
Gao-Feng Shi ◽  
Ya-Ning Wang ◽  
Qi Wang ◽  
Hui Feng
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Low Dose ◽  
Lung Nodule ◽  
Pulmonary Nodules ◽  
Lung Cancer Screening ◽  
Tube Voltage ◽  
Conventional Dose ◽  
Tube Current ◽  
Lung Screening

Abstract Background Lung cancer screening revealed that people with small pulmonary nodules are mostly asymptomatic and that some of these people are at risk of developing lung cancer, so we intended to explore the repeatability of small lung nodule measurement in low-dose lung screening. Methods We scanned eight ground-glass nodules (GGNs) and solid nodules, with diameters of 3, 5, 8, and 10 mm. They were divided according to the different combination schemes of tube voltage (KV) and tube current (mA) as 70, 80, 100, and 120 KV, and currents of nine tubes were divided as 20, 30, 40, 50, 60, 70, 80, 90, and 100 mAs. Results Compared with the conventional dose group (120 kVp, 100 mAs), the nodule diameter and solid nodule volume measured by all scanning combinations were more consistent (P > 0.05), the volumes of 10 mm GGNs combinations were consistent (P > 0.05), the volumes of 8 mm GGNs were consistent (P > 0.05), the volumes of 5 mm GGNs combinations were consistent (P > 0.05), and the volumes of 3 mm were consistent (P > 0.05). Conclusion In lung cancer screening, CT parameters should be as follows: tube voltage is more than 80 kVp, and tube current is 80 mAs in order to meet the requirements for the accurate measurement of the diameter and volume of pulmonary nodules.

Optimal tube current for lung cancer screening with low-dose spiral CT

2000 ◽  
Vol 41 (4) ◽  
pp. 352-356 ◽  
Author(s):  
K. Oguchi ◽  
S. Sone ◽  
K. Kiyono ◽  
S. Takashima ◽  
Y. Maruyama ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Low Dose ◽  
Lung Cancer Screening ◽  
Spiral Ct ◽  
Tube Current

LOW-DOSE COMPUTED TOMOGRAPHY IN MOSCOW FOR LUNG CANCER SCREENING (LDCT-MLCS): BASELINE RESULTS

2019 ◽  
Vol 65 (2) ◽  
pp. 224-233
Author(s):  
Sergey Morozov ◽  
Viktor Gombolevskiy ◽  
Anton Vladzimirskiy ◽  
Albina Laypan ◽  
Pavel Kononets ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Cancer Screening ◽  
Low Dose ◽  
Early Stage ◽  
Lung Cancer Screening ◽  
Stage I ◽  
Malignant Neoplasms ◽  
Number Needed To Screen ◽  
Low Dose Computed Tomography

Study aim. To justify selective lung cancer screening via low-dose computed tomography and evaluate its effectiveness. Materials and methods. In 2017 we have concluded the baseline stage of “Lowdose computed tomography in Moscow for lung cancer screening (LDCT-MLCS)” trial. The trial included 10 outpatient clinics with 64-detector CT units (Toshiba Aquilion 64 and Toshiba CLX). Special low-dose protocols have been developed for each unit with maximum effective dose of 1 mSv (in accordance with the requirements of paragraph 2.2.1, Sanitary Regulations 2.6.1.1192-03). The study involved 5,310 patients (53% men, 47% women) aged 18-92 years (mean age 62 years). Diagnosis verification was carried out in the specialized medical organizations via consultations, additional instrumental, laboratory as well as pathohistological studies. The results were then entered into the “National Cancer Registry”. Results. 5310 patients (53% men, 47% women) aged 18 to 92 years (an average of 62 years) participated in the LDCT-MLCS. The final cohort was comprised of 4762 (89.6%) patients. We have detected 291 (6.1%) Lung-RADS 3 lesions, 228 (4.8%) Lung- RADS 4A lesions and 196 (4.1%) Lung-RADS 4B/4X lesions. All 4B and 4X lesions were routed in accordance with the project's methodology and legislative documents. Malignant neoplasms were verified in 84 cases (1.76% of the cohort). Stage I-II lung cancer was actively detected in 40.3% of these individuals. For the first time in the Russian Federation we have calculated the number needed to screen (NNS) to identify one lung cancer (NNS=57) and to detect one Stage I lung cancer (NNS=207). Conclusions. Based on the global experience and our own practices, we argue that selective LDCT is the most systematic solution to the problem of early-stage lung cancer screening.

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