Hypothalamo-pituitary-adrenal axis integrity after cranial irradiation for childhood posterior fossa tumours

2003 ◽  
Vol 40 (4) ◽  
pp. 224-229 ◽  
Author(s):  
H.A. Spoudeas ◽  
E. Charmandari ◽  
C.G.D. Brook

2012 ◽  
Vol 32 (7) ◽  
pp. 1175-1185 ◽  
Author(s):  
Nataša Veličković ◽  
Dunja Drakulić ◽  
Snježana Petrović ◽  
Ivana Grković ◽  
Maja Milošević ◽  
...  






1970 ◽  
Vol 65 (4) ◽  
pp. 608-616 ◽  
Author(s):  
M. J. Levell ◽  
S. R. Stitch ◽  
M. J. Noronha

ABSTRACT Pituitary-adrenal function was tested in a group of 33 patients with multiple sclerosis who had been treated with corticotrophin for at least 1 year. Assessment was made by measuring the change in the plasma 11-hydroxycorticosteroid concentration following lysine vasopressin (LVP) administration. Ten patients showed abnormally small increases after LVP. Two of the 5 patients with the smallest increases still showed impairment 8 months later. The patients with no withdrawal symptoms had normal or nearly normal increases following LVP. There was an association between the concentration of 11-hydroxycorticosteroids immediately after withdrawal of ACTH and the subsequent response to LVP.



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