scholarly journals Myocardial arterial spin labeling in systole and diastole using flow‐sensitive alternating inversion recovery with parallel imaging and compressed sensing

2020 ◽  
Vol 34 (2) ◽  
Author(s):  
Markus Henningsson ◽  
Carl‐Johan Carlhäll ◽  
Johan Kihlberg

2019 ◽  
Author(s):  
Sophie Schauman ◽  
Mark Chiew ◽  
Thomas W. Okell

AbstractPurposeTo demonstrate that vessel-selectivity in arterial spin labeling angiography can be achieved without any scan time penalty or noticeable loss of image quality compared to conventional arterial spin labeling angiography.MethodsSimulations on a numerical phantom were used to assess whether the increased sparsity of vessel-encoded angiograms compared to non-vessel-encoded angiograms alone can improve reconstruction results in a compressed sensing framework. Further simulations were performed to study whether the difference in relative sparsity between non-selective and vessel-selective dynamic angiograms were sufficient to achieve similar image quality at matched scan times in the presence of noise. Finally, data were acquired from 5 healthy volunteers to validate the technique in vivo. All data, both simulated and in vivo, were sampled in 2D using a golden angle radial trajectory and reconstructed by enforcing both image domain sparsity and temporal smoothness on the angiograms in a parallel imaging and compressed sensing framework.ResultsRelative sparsity was established as a primary factor governing the reconstruction fidelity. Using the proposed reconstruction scheme, differences between vessel-selective and non-selective angiography were negligible compared to the dominant factor of total scan time in both simulations and in vivo experiments at acceleration factors up to R = 34. The reconstruction quality was not heavily dependent on hand-tuning the parameters of the reconstruction.ConclusionThe increase in relative sparsity of vessel-selective angiograms compared to non-selective angiograms can be leveraged to achieve higher acceleration without loss of image quality, resulting in the acquisition of vessel-selective information at no scan time cost.







2011 ◽  
Vol 67 (2) ◽  
pp. 477-483 ◽  
Author(s):  
Marcelo E. Andia ◽  
Rene M. Botnar


2019 ◽  
Author(s):  
Eleanor S. K. Berry ◽  
Peter Jezzard ◽  
Thomas W. Okell

AbstractObjectTo demonstrate the advantages of radial k-space trajectories over conventional Cartesian approaches for accelerating the acquisition of vessel-selective arterial spin labeling (ASL) dynamic angiograms, which are conventionally time-consuming to acquire.Materials and MethodsVessel-encoded pseudocontinuous ASL was combined with time-resolved balanced steady-state free precession (bSSFP) and spoiled gradient echo (SPGR) readouts to obtain dynamic vessel-selective angiograms arising from the four main brain-feeding arteries. Dynamic 2D protocols with acquisition times of one minute or less were achieved through radial undersampling or a Cartesian parallel imaging approach. For whole-brain dynamic 3D imaging, magnetic field inhomogeneity and the high acceleration factors required rule out the use of bSSFP and Cartesian trajectories, so the feasibility of acquiring 3D radial SPGR angiograms was tested.ResultsThe improved SNR efficiency of bSSFP over SPGR was confirmed for 2D dynamic imaging. Radial trajectories had considerable advantages over a Cartesian approach, including a factor of two improvement in the measured SNR (p<0.00001, N=6), improved distal vessel delineation and the lack of a need for calibration data. The 3D radial approach produced good quality angiograms with negligible artifacts despite the high acceleration factor (R=13).ConclusionRadial trajectories outperform conventional Cartesian techniques for accelerated vessel-selective ASL dynamic angiography.



2012 ◽  
Vol 35 (5) ◽  
pp. 1233-1239 ◽  
Author(s):  
Jean-Christophe Ferré ◽  
Jan Petr ◽  
Elise Bannier ◽  
Christian Barillot ◽  
Jean-Yves Gauvrit




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