High‐contrast osteochondral junction imaging using a 3D dual adiabatic inversion recovery‐prepared ultrashort echo time cones sequence

2021 ◽  
Author(s):  
Alecio F. Lombardi ◽  
Hyungseok Jang ◽  
Zhao Wei ◽  
Saeed Jerban ◽  
Mark Wallace ◽  
...  
Keyword(s):  
Inversion Recovery ◽  
High Contrast ◽  
Ultrashort Echo Time ◽  
Echo Time ◽  
Adiabatic Inversion

High contrast cartilaginous endplate imaging using a 3D adiabatic inversion‐recovery‐prepared fat‐saturated ultrashort echo time (3D IR‐FS‐UTE) sequence

2021 ◽  
Author(s):  
Alecio F. Lombardi ◽  
Zhao Wei ◽  
Jonathan Wong ◽  
Michael Carl ◽  
Roland R. Lee ◽  
...  
Keyword(s):  
Inversion Recovery ◽  
High Contrast ◽  
Ultrashort Echo Time ◽  
Echo Time ◽  
Adiabatic Inversion ◽  
Cartilaginous Endplate

scholarly journals Myelin Imaging in Human Brain Using a Short Repetition Time Adiabatic Inversion Recovery Prepared Ultrashort Echo Time (STAIR-UTE) MRI Sequence in Multiple Sclerosis

Radiology ◽  
2020 ◽  
Vol 297 (2) ◽  
pp. 392-404 ◽  
Author(s):  
Ya-Jun Ma ◽  
Hyungseok Jang ◽  
Zhao Wei ◽  
Zhenyu Cai ◽  
Yanping Xue ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Human Brain ◽  
Inversion Recovery ◽  
Ultrashort Echo Time ◽  
Repetition Time ◽  
Echo Time ◽  
Adiabatic Inversion ◽  
Myelin Imaging

scholarly journals Feasibility of an Inversion Recovery-Prepared Fat-Saturated Zero Echo Time Sequence for High Contrast Imaging of the Osteochondral Junction

2021 ◽  
Vol 12 ◽  
Author(s):  
Hyungseok Jang ◽  
Yajun Ma ◽  
Michael Carl ◽  
Alecio F. Lombardi ◽  
Eric Y. Chang ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Ex Vivo ◽  
Inversion Recovery ◽  
High Contrast ◽  
Contrast Imaging ◽  
Tibial Cartilage ◽  
High Contrast Imaging ◽  
Echo Time ◽  
Adiabatic Inversion

PurposeThe osteochondral junction (OCJ) region—commonly defined to include the deep radial uncalcified cartilage, tidemark, calcified cartilage, and subchondral bone plate—functions to absorb mechanical stress and is commonly associated with the pathogenesis of osteoarthritis. However, magnetic resonance imaging of the OCJ region is difficult due to the tissues’ short transverse relaxation times (i.e., short T2 or T2*), which result in little or no signal with conventional MRI. The goal of this study is to develop a 3D adiabatic inversion recovery prepared fat saturated zero echo time (IR-FS-ZTE) sequence for high-contrast imaging of the OCJ.MethodAn IR-FS-ZTE MR sequence was developed to image the OCJ on a clinical 3T MRI scanner. The IR-FS-ZTE sequence employed an adiabatic inversion pulse followed by a fat saturation pulse that suppressed signals from the articular cartilage and fat. At an inversion time (TI) that was matched to the nulling point of the articular cartilage, continuous ZTE imaging was performed with a smoothly rotating readout gradient, which enabled time-efficient encoding of the OCJ region’s short T2 signal with a minimal echo time (TE) of 12 μs. An ex vivo experiment with six cadaveric knee joints, and an in vivo experiment with six healthy volunteers and three patients with OA were performed to evaluate the feasibility of the proposed approach for high contrast imaging of the OCJ. Contrast-to-noise ratios (CNRs) between the OCJ and its neighboring femoral and tibial cartilage were measured.ResultsIn the ex vivo experiment, IR-FS-ZTE produced improved imaging of the OCJ region over the clinical sequences, and significantly improved the contrast compared to FS-ZTE without IR preparation (p = 0.0022 for tibial cartilage and p = 0.0019 for femoral cartilage with t-test). We also demonstrated the feasibility of high contrast imaging of the OCJ region in vivo using the proposed IR-FS-ZTE sequence, thereby providing more direct information on lesions in the OCJ. Clinical MRI did not detect signal from OCJ due to the long TE (>20 ms).ConclusionIR-FS-ZTE allows direct imaging of the OCJ region of the human knee and may help in elucidating the role of the OCJ in cartilage degeneration.

scholarly journals Dual inversion recovery, ultrashort echo time (DIR UTE) imaging: Creating high contrast for short-T 2 species

2010 ◽  
Vol 63 (2) ◽  
pp. 447-455 ◽  
Author(s):  
Jiang Du ◽  
Atsushi M. Takahashi ◽  
Won C. Bae ◽  
Christine B. Chung ◽  
Graeme M. Bydder
Keyword(s):  
Inversion Recovery ◽  
High Contrast ◽  
Ultrashort Echo Time ◽  
Echo Time

scholarly journals Imaging of the region of the osteochondral junction (OCJ) using a 3D adiabatic inversion recovery prepared ultrashort echo time cones (3D IR‐UTE‐cones) sequence at 3 T

2019 ◽  
Vol 32 (5) ◽  
pp. e4080 ◽  
Author(s):  
Ya‐Jun Ma ◽  
Saeed Jerban ◽  
Michael Carl ◽  
Lidi Wan ◽  
Tan Guo ◽  
...  
Keyword(s):  
Inversion Recovery ◽  
Ultrashort Echo Time ◽  
Echo Time ◽  
Adiabatic Inversion

scholarly journals T 1 measurement of bound water in cortical bone using 3D adiabatic inversion recovery ultrashort echo time (3D IR‐UTE) Cones imaging

2019 ◽  
Vol 84 (2) ◽  
pp. 634-645 ◽  
Author(s):  
Tan Guo ◽  
Yajun Ma ◽  
Saeed Jerban ◽  
Hyungseok Jang ◽  
Wei Zhao ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Bound Water ◽  
Inversion Recovery ◽  
Ultrashort Echo Time ◽  
Echo Time ◽  
Adiabatic Inversion

scholarly journals Three-dimensional adiabatic inversion recovery prepared ultrashort echo time cones (3D IR-UTE-Cones) imaging of cortical bone in the hip

2017 ◽  
Vol 44 ◽  
pp. 60-64 ◽  
Author(s):  
Amin Nazaran ◽  
Michael Carl ◽  
Yajun Ma ◽  
Saeed Jerban ◽  
Yanchun Zhu ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Three Dimensional ◽  
Inversion Recovery ◽  
Ultrashort Echo Time ◽  
Echo Time ◽  
Adiabatic Inversion

scholarly journals Short T 2 imaging using a 3D double adiabatic inversion recovery prepared ultrashort echo time cones (3D DIR‐UTE‐Cones) sequence

2017 ◽  
Vol 79 (5) ◽  
pp. 2555-2563 ◽  
Author(s):  
Ya‐Jun Ma ◽  
Yanchun Zhu ◽  
Xing Lu ◽  
Michael Carl ◽  
Eric Y. Chang ◽  
...  
Keyword(s):  
Inversion Recovery ◽  
Ultrashort Echo Time ◽  
Echo Time ◽  
Adiabatic Inversion

scholarly journals Volumetric imaging of myelin in vivo using 3D inversion recovery‐prepared ultrashort echo time cones magnetic resonance imaging

2020 ◽  
Vol 33 (10) ◽  
Author(s):  
Ya‐Jun Ma ◽  
Adam C. Searleman ◽  
Hyungseok Jang ◽  
Shu‐Juan Fan ◽  
Jonathan Wong ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Inversion Recovery ◽  
Resonance Imaging ◽  
3D Inversion ◽  
Ultrashort Echo Time ◽  
Volumetric Imaging ◽  
Echo Time

scholarly journals Using adiabatic inversion pulses for long-T2 suppression in ultrashort echo time (UTE) imaging

2007 ◽  
Vol 58 (5) ◽  
pp. 952-961 ◽  
Author(s):  
Peder E. Z. Larson ◽  
Steven M. Conolly ◽  
John M. Pauly ◽  
Dwight G. Nishimura
Keyword(s):  
Ultrashort Echo Time ◽  
Echo Time ◽  
Adiabatic Inversion ◽  
Inversion Pulses
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