Unmasking the potential role of plant‐based medicine “Plumbagin” in oral cancer—A Novel Paradigm

2021 ◽  
Author(s):  
Neeraj Taneja ◽  
Aftab Alam ◽  
Ranjana S. Patnaik ◽  
Tannu Taneja
BMC Cancer ◽  
2016 ◽  
Vol 16 (S1) ◽  
Author(s):  
Muraleedharan Parvathy ◽  
Sreeharshan Sreeja ◽  
Rakesh Kumar ◽  
Madhavan Radhakrishna Pillai

Oral Oncology ◽  
2018 ◽  
Vol 80 ◽  
pp. 97 ◽  
Author(s):  
Archana A. Gupta ◽  
Nikhil Pande ◽  
Supriya Kheur ◽  
A. Thirumal Raj

Author(s):  
MAIANE NASCIMENTO ◽  
THAIS GONÇALES DOS SANTOS ANDRADE ◽  
PAULA SENA DA MATA ◽  
CLAUDIA YUMI MAEDA ◽  
PRISCILA SANTANA DA SILVA ◽  
...  

2019 ◽  
Vol 47 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Thomas Brand

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.


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