World health organization international histological classification of tumours: Histological typing of salivary gland tumours. G. Seifert (Ed.). Springer-Verlag, Heidelberg, 1991. No. of pages: 112. Price: DM 68. ISBN: 0 387 54031

1992 ◽  
Vol 168 (1) ◽  
pp. 88-88
Author(s):  
P. M. Speight
Keyword(s):  
Salivary Gland ◽  
World Health Organization ◽  
World Health ◽  
Histological Classification ◽  
Salivary Gland Tumours ◽  
Histological Typing ◽  
Health Organization

Investigation of the Applicability of Histological Classification of Bronchial Carcinoma According to the World Health Organization

1989 ◽  
Vol 75 (6) ◽  
pp. 580-582
Author(s):  
Mirjana Čačić ◽  
Božidar Oberman ◽  
Gordan Dvornik
Keyword(s):  
World Health Organization ◽  
Cell Carcinoma ◽  
Bronchial Carcinoma ◽  
Giant Cells ◽  
World Health ◽  
Histological Classification ◽  
Clear Cells ◽  
The World ◽  
Health Organization

According to the World Health Organization histological classification of bronchial tumors, clear and giant cell carcinomas are two subtypes of large cell carcinoma. As clear and giant cells can also be observed in other types of bronchial carcinoma, we investigated the frequency of the finding of these cells in different histological types. The tumor size and degree of differentiation, the amount of necrosis and keratinization, and the presence of giant and clear cells were analyzed. Statistical analysis by χ2 test showed (for all classified histological types of bronchial carcinomas, except small cell carcinoma) that: 1) larger tumors had a great quantity of giant cells (P < 0.05; P < 0.01), 2) large tumors had more clear cells (P < 0.05; P < 0.01) and 3) tumors with a greater amount of necrosis had a larger number of giant and clear cells (P<0.05; P < 0.01). Findings of an identical cytological characteristic can cause some difficulty in determination of bronchial cancer.

Odontogenic Carcinoma With Dentinoid in Long-Term Follow-up With 2 Recurrences

2019 ◽  
Vol 28 (2) ◽  
pp. 181-187 ◽  
Author(s):  
Fernanda Viviane Mariano ◽  
Rogério Oliveira Gondak ◽  
João Figueira Scarini ◽  
Eduardo Caetano Albino da Silva ◽  
Gisele Caravina ◽  
...  
Keyword(s):  
World Health Organization ◽  
World Health ◽  
Odontogenic Tumors ◽  
Ossifying Fibroma ◽  
Histological Classification ◽  
Cytological Evidence ◽  
Odontogenic Carcinoma ◽  
Health Organization

Dentinoid has been mentioned as a frequent component in several types of benign odontogenic tumors; however, there are some other very rare dentinoid-producing odontogenic tumors that have been described, which are not recognized in the current World Health Organization Histological Classification of Odontogenic Tumours. In this context, we report an unusual malignant odontogenic tumor containing dentinoid located in the left maxilla of a 41-year-old man. The lesion was initially diagnosed and treated as a cemento-ossifying fibroma. After 7 years, a tumor was noted at the same location and was diagnosed as pleomorphic adenoma. The patient developed a new lesion 2 years later. Histological features included an epithelial proliferation of basaloid and clear cells, some with peripheral palisading, which were scattered both in a fibrous stroma and within an amorphous eosinophilic dentinoid product. Because of doubts about the first 2 diagnoses and the current situation, all histopathological slides were reviewed in our service as a consultation case, and the findings were consistent with the diagnosis of an odontogenic carcinoma with dentinoid. Immunohistochemical analysis was performed and an ultrastructural study by scanning electronic microscopy and energy-dispersive X-ray microanalysis was made to characterize dentinoid material. After 1 year of follow-up, the patient is alive and free of the disease. This case highlights the wide variability regarding cytological evidence of malignancy, and adds a new case of odontogenic carcinoma with dentinoid, which represents a distinct entity with locally aggressive behavior and should be considered be included in a future World Health Organization Histological Classification of Tumours.

scholarly journals Estratégia cirúrgica para tratamento de adenoma pleomórfico de grande tamanho: relato de caso

2019 ◽  
Vol 8 (8) ◽  
Author(s):  
Breno dos Reis Fernandes ◽  
Darah Ligia Marchirori ◽  
Oswaldo Belloti Neto ◽  
Patrese Pereira de Bella ◽  
Gabriel Mulinari dos Santos ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
World Health ◽  
Histological Classification ◽  
Parotid Surgery ◽  
Classification Of Tumors ◽  
Health Organization ◽  
Parotid Tumours ◽  
Head Neck

As neoplasias da glândula parótida constituem um grupo heterogêneo com mais de 30 tipos histológicos definidos, sendo o adenoma pleomórfico o tumor benigno mais comum. Neste artigo é relatado um caso clínico onde o tumor apresentou evolução de um ano, sem sintomatologia associada, gerando assimetria facial ao paciente, sendo realizado tratamento cirúrgico conservador apenas por enucleação da lesão, visando reduzir cirurgias maiores como a parotidectomias parciais ou totais. Após acompanhamento de 5 anos o paciente não apresenta sequelas do tratamento cirúrgico, nem sinal de recorrência da lesão.Descritores: Adenoma Pleomorfo; Glândula Parótida; Relatos de Casos.ReferênciasSeifert G, Sobin L. Histological typing of salivary gland tumors. World Health Organization. International histological classification of tumors, 2.ed. Berlin: Springer-Verlag; 1991.Spiro RH. Salivary neoplasms: overview of a 35-year experience with 2807 patients. Head Neck Surg. 1986; 8(3):177-84Witt RL. The significance of the margin in parotid surgery for pleomorphic adenoma. Laryngoscope 2002; 112(12):2141-54Louro RS, Passeado D, Andrade MC, Sampaio RKPL. Adenoma pleomórfico em palato duro: relato de caso clínico. Rev Bras Odontol. 2002;59(1):25-7.Nogueira AS, Alves APNN, Nogueira RAS, Tavares RN. Adenoma pleomórfico no palato duro: relato de caso clínico. Rev Paul Odontol. 2001;23(1):14-8.Ribeiro-Rotta RF, Cruz Ml, Paiva RR, Mendonça EF, Spini TH, Mendonça AR. O papel da ressonância magnética no diagnóstico do adenoma pleomórfico: revisão da literatura e relato de casos. Rev Bras Otorrinolaringol. 2003;69(5):699-707.van der Wal JE, Leverstein H, Snow GB, Kraaijenhagen HA, van der Waal I. Parotid gland tumors: histologic reevaluation and reclassification of 478 cases. Head Neck. 1998; 20(3):204-7.Cohen MA. Pleomorphic adenoma of the cheek. Int J Oral Maxillofac Surg. 1986; 15(6):777-9.Tiago RSL, Castro GA, Ricardo LAC, Biihler RB, Fava AS. Adenoma pleomórfico de parótida: aspectos clínicos, diagnósticos e terapêuticos. Rev Bras Otorrinolaringol. 2003;69(4):485-89.Kamal SA, Othman EO. Diagnosis and treatment of parotid tumours. J Laringol Otol. 1997; 111(4):316-21Nogueira AS, Alves APNN, Nogueira RAS, Tavares RN. Adenoma pleomórfico no palato duro: relato de caso clínico. Rev Paul Odontol. 2001;23(1):14-8Neville BW, Damm DD, Allen CM, Bouquot JE. Patologia oral e maxilofacial. 2. ed. Rio de Janeiro: Guanabara Koogan; 2004.

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