Most low-level microsatellite instability in colorectal cancers can be explained without an elevated slippage rate

2008 ◽  
Vol 215 (2) ◽  
pp. 204-210 ◽  
Author(s):  
T Graham ◽  
S Halford ◽  
KM Page ◽  
IPM Tomlinson
Keyword(s):  
Microsatellite Instability ◽  
Colorectal Cancers ◽  
Slippage Rate ◽  
Low Level

Somatic hMLH3 frameshift mutation in colorectal cancers with microsatellite instability

2001 ◽  
Vol 120 (5) ◽  
pp. A295-A295
Author(s):  
D CHANG ◽  
A GOEL ◽  
L RICCIARDIELLO ◽  
C ARNOLD ◽  
C BOLAND
Keyword(s):  
Microsatellite Instability ◽  
Frameshift Mutation ◽  
Colorectal Cancers

Mo1656 Microsatellite Instability of the Gastric and Colorectal Cancers As a Predictor for Synchronous Gastrointestinal Neoplasms

2014 ◽  
Vol 146 (5) ◽  
pp. S-628
Author(s):  
Young Baek Kim ◽  
Sun-Young Lee ◽  
Jeong Hwan Kim ◽  
In Kyung Sung ◽  
Hyung Seok Park ◽  
...  
Keyword(s):  
Microsatellite Instability ◽  
Gastrointestinal Neoplasms ◽  
Colorectal Cancers

Differential clinicopathological features in microsatellite instability-positive colorectal cancers depending on CIMP status

2011 ◽  
Vol 459 (1) ◽  
pp. 55-63 ◽  
Author(s):  
Jeong Mo Bae ◽  
Mi Jung Kim ◽  
Jung Ho Kim ◽  
Jae Moon Koh ◽  
Nam-Yun Cho ◽  
...  
Keyword(s):  
Microsatellite Instability ◽  
Clinicopathological Features ◽  
Colorectal Cancers

Identification of Candidate Oncogenes in Human Colorectal Cancers With Microsatellite Instability

2013 ◽  
Vol 145 (3) ◽  
pp. 540-543.e22 ◽  
Author(s):  
Alexandra E. Gylfe ◽  
Johanna Kondelin ◽  
Mikko Turunen ◽  
Heikki Ristolainen ◽  
Riku Katainen ◽  
...  
Keyword(s):  
Microsatellite Instability ◽  
Colorectal Cancers

scholarly journals Serrated Polyps and Serrated Polyposis Syndrome

2016 ◽  
Vol 29 (04) ◽  
pp. 336-344 ◽  
Author(s):  
Jean Ashburn ◽  
Thomas Plesec ◽  
Matthew Kalady
Keyword(s):  
Microsatellite Instability ◽  
Clinical Management ◽  
Promoter Hypermethylation ◽  
Colorectal Cancers ◽  
Polyposis Syndrome ◽  
Management Guidelines ◽  
Serrated Polyps

AbstractColorectal serrated polyps are intermediate lesions in the serrated neoplastic pathway, which account for up to 30% of colorectal cancers. This pathway is biologically distinct from the adenoma-to-carcinoma sequence, with associated cancers exhibiting mutations in the BRAF oncogene, DNA promoter hypermethylation, and microsatellite instability. An evolving understanding of these unique lesions has led to the development of a more accurate classification, improved endoscopic identification, and tailored clinical management guidelines. This article reviews serrated polyps and serrated polyposis syndrome.

Microsatellite instability in young patients with mucinous colorectal cancers – characterization using molecular testing, immunohistochemistry, and histological features

2019 ◽  
Vol 56 (4) ◽  
pp. 309
Author(s):  
NittySkariah Mathews ◽  
Dipti Masih ◽  
Rohin Mittal ◽  
Benjamin Perakath ◽  
Dhananjayan Sakthi ◽  
...  
Keyword(s):  
Microsatellite Instability ◽  
Young Patients ◽  
Colorectal Cancers ◽  
Molecular Testing ◽  
Histological Features

scholarly journals The value of microsatellite instability in the detection of HNPCC families and of sporadic colorectal cancers with special biological features: An investigation on a series of 100 consecutive cases

1998 ◽  
Vol 9 (8) ◽  
pp. 901-906 ◽  
Author(s):  
D. Furlan ◽  
M.G. Tibiletti ◽  
M. Taborelli ◽  
L. Albarello ◽  
M. Cornaggia ◽  
...  
Keyword(s):  
Microsatellite Instability ◽  
Colorectal Cancers ◽  
Biological Features
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