Short‐term and long‐term outcomes after preventive surgery in adolescent patients with familial adenomatous polyposis

Background Many patients with familial adenomatous polyposis (FAP) have adenomatous polyps of the duodenum and the jejunum. We aimed to elucidate the long-term outcomes after double-balloon endoscopy (DBE)-assisted endoscopic resection of duodenal and jejunal polyps in patients with FAP. Methods We retrospectively reviewed patients who underwent more than two sessions of endoscopic resection using DBE from August 2004 to July 2018. Results A total of 72 DBEs were performed in eight patients (median 30 years old, range 12-53, 1.4 DBE procedures/patient-year) during the study period and 1237 polyps were resected. The median observation period was 77.5 months (range 8 to 167). There were 11 adverse events, including 7 with delayed bleeding and 4 with acute pancreatitis. No delayed bleeding occurred after cold polypectomy. Although one endoscopically-resected polyp in the duodenum was diagnosed as intramucosal carcinoma in one patient, no patient developed an advanced duodenal or jejunal cancer during the study period. Conclusions Endoscopic resection of duodenal and jejunal polyposis using DBE in patients with FAP can be performed safely, efficiently and effectively.

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Long-Term Outcomes of Pancreas-Sparing Duodenectomy for Duodenal Polyposis in Familial Adenomatous Polyposis Syndrome

Journal of Gastrointestinal Surgery ◽

10.1007/s11605-020-04621-7 ◽

2020 ◽

Cited By ~ 2

Author(s):

Robert Naples ◽

Robert Simon ◽

Maitham Moslim ◽

Toms Augustin ◽

James Church ◽

...

Keyword(s):

Familial Adenomatous Polyposis ◽

Adenomatous Polyposis ◽

Long Term Outcomes ◽

Polyposis Syndrome ◽

Duodenal Polyposis

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Abstract #238: Improved Short Term and Long Term Outcomes of Early Insulin Initiation in Type 2 Diabetes Over 10 Years

Endocrine Practice ◽

10.1016/s1530-891x(20)44358-7 ◽

2017 ◽

Vol 23 ◽

pp. 50

Author(s):

Jothydev Kesavadev ◽

Shashank Joshi ◽

Banshi Saboo ◽

Hemant Thacker ◽

Arun Shankar ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Initiation ◽

Long Term Outcomes ◽

Short Term

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Effect of Thrombocytopenia on Short-term and Long-term Outcomes after Esophagectomy for Esophageal Cancer

Nihon Kikan Shokudoka Gakkai Kaiho ◽

10.2468/jbes.69.327 ◽

2018 ◽

Vol 69 (6) ◽

pp. 327-334

Author(s):

Takashi Matsumoto ◽

Naoya Yoshida ◽

Yoshifumi Baba ◽

Yohei Nagai ◽

Hideo Baba

Keyword(s):

Esophageal Cancer ◽

Long Term Outcomes ◽

Short Term

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Short-term and long-term outcomes in living donors for liver transplantation: Cohort study

International Journal of Surgery ◽

10.1016/j.ijsu.2020.11.013 ◽

2020 ◽

Vol 84 ◽

pp. 147-153

Author(s):

Kosei Takagi ◽

Yuzo Umeda ◽

Ryuichi Yoshida ◽

Nobuyuki Watanabe ◽

Takashi Kuise ◽

...

Keyword(s):

Liver Transplantation ◽

Cohort Study ◽

Living Donors ◽

Long Term Outcomes ◽

Short Term

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Robotic and laparoscopic liver surgery for colorectal liver metastases: an experience from a German Academic Center

World Journal of Surgical Oncology ◽

10.1186/s12957-020-02113-1 ◽

2020 ◽

Vol 18 (1) ◽

Author(s):

Mirhasan Rahimli ◽

Aristotelis Perrakis ◽

Vera Schellerer ◽

Andrew Gumbs ◽

Eric Lorenz ◽

...

Keyword(s):

Abdominal Surgery ◽

Minimally Invasive ◽

Liver Surgery ◽

Colorectal Liver Metastases ◽

Survival Rates ◽

Long Term Outcomes ◽

Short Term ◽

Minimally Invasive Liver Surgery ◽

Previous Abdominal Surgery

Abstract Background Minimally invasive liver surgery (MILS) in the treatment of colorectal liver metastases (CRLM) is increasing in incidence. The aim of this work was to present our experience by reporting short-term and long-term outcomes after MILS for CRLM with comparative analysis of laparoscopic (LLS) and robotic liver surgery (RLS). Methods Twenty-five patients with CRLM, who underwent MILS between May 2012 and March 2020, were selected from our retrospective registry of minimally invasive liver surgery (MD-MILS). Thirteen of these patients underwent LLS and 12 RLS. Short-term and long-term outcomes of both groups were analyzed. Results Operating time was significantly longer in the RLS vs. the LLS group (342.0 vs. 200.0 min; p = 0.004). There was no significant difference between the laparoscopic vs. the robotic group regarding length of postoperative stay (8.8 days), measured blood loss (430.4 ml), intraoperative blood transfusion, overall morbidity (20.0%), and liver surgery related morbidity (4%). The mean BMI was 27.3 (range from 19.2 to 44.8) kg/m2. The 30-day mortality was 0%. R0 resection was achieved in all patients (100.0%) in RLS vs. 10 patients (76.9%) in LLS. Major resections were carried out in 32.0% of the cases, and 84.0% of the patients showed intra-abdominal adhesions due to previous abdominal surgery. In 24.0% of cases, the tumor was bilobar, the maximum number of tumors removed was 9, and the largest tumor was 8.5 cm in diameter. The 1-, 3- and 5-year overall survival rates were 84, 56.9, and 48.7%, respectively. The 1- and 3-year overall recurrence-free survival rates were 49.6 and 36.2%, respectively, without significant differences between RLS vs. LLS. Conclusion Minimally invasive liver surgery for CRLM is safe and feasible. Minimally invasive resection of multiple lesions and large tumors is also possible. RLS may help to achieve higher rates of R0 resections. High BMI, previous abdominal surgery, and bilobar tumors are not a barrier for MILS. Laparoscopic and robotic liver resections for CRLM provide similar long-term results which are comparable to open techniques.

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