Cell‐free DNA for Down syndrome screening in obese women: Is it a cost‐effective strategy?

2019 ◽  
Vol 40 (2) ◽  
pp. 173-178
Author(s):  
Maeve K. Hopkins ◽  
Lorraine Dugoff ◽  
Celeste Durnwald ◽  
Laura J. Havrilesky ◽  
Sarah Dotters‐Katz
2019 ◽  
Vol 220 (1) ◽  
pp. S583-S584
Author(s):  
Maeve Hopkins ◽  
Lorraine Dugoff ◽  
Celeste Durnwald ◽  
Laura Havrilesky ◽  
Sarah Dotters-Katz

2018 ◽  
Vol 48 (4) ◽  
pp. 461-470 ◽  
Author(s):  
Kathryn J. Gray ◽  
Louise E. Wilkins-Haug

2013 ◽  
Vol 33 (11) ◽  
pp. 1044-1049 ◽  
Author(s):  
J Johnson ◽  
M Pastuck ◽  
A Metcalfe ◽  
G Connors ◽  
R Krause ◽  
...  

2021 ◽  
Vol 55 (2) ◽  
pp. 565-583
Author(s):  
Ke Zhan ◽  
Quanxiong Lu ◽  
Sengwei Xia ◽  
Congnan Guo ◽  
Sisi Zhao ◽  
...  

2021 ◽  
Vol 72 (1) ◽  
pp. 399-413
Author(s):  
Van K. Morris ◽  
John H. Strickler

Patient-specific biomarkers form the foundation of precision medicine strategies. To realize the promise of precision medicine in patients with colorectal cancer (CRC), access to cost-effective, convenient, and safe assays is critical. Improvements in diagnostic technology have enabled ultrasensitive and specific assays to identify cell-free DNA (cfDNA) from a routine blood draw. Clinicians are already employing these minimally invasive assays to identify drivers of therapeutic resistance and measure genomic heterogeneity, particularly when tumor tissue is difficult to access or serial sampling is necessary. As cfDNA diagnostic technology continues to improve, more innovative applications are anticipated. In this review, we focus on four clinical applications for cfDNA analysis in the management of CRC: detecting minimal residual disease, monitoring treatment response in the metastatic setting, identifying drivers of treatment sensitivity and resistance, and guiding therapeutic strategies to overcome resistance.


1995 ◽  
Vol 108 (4) ◽  
pp. A18 ◽  
Author(s):  
I Hussain ◽  
WH Farrar ◽  
EJ Sofian ◽  
TF Bader ◽  
JD Strom ◽  
...  

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