Steady-state permeation of carbon dioxide through a miscible, glassy polymer blend

1996 ◽  
Vol 34 (16) ◽  
pp. 2689-2699 ◽  
Author(s):  
S. Chin ◽  
T. Gaskins ◽  
C. J. Durning
Keyword(s):  
Carbon Dioxide ◽  
Steady State ◽  
Polymer Blend ◽  
Glassy Polymer

Respiration in man during metabolic alkalosis

1962 ◽  
Vol 17 (1) ◽  
pp. 33-37 ◽  
Author(s):  
Daniel J. Stone
Keyword(s):  
Carbon Dioxide ◽  
Steady State ◽  
Lung Function ◽  
Gas Exchange ◽  
Metabolic Alkalosis ◽  
Time Lag ◽  
Respiratory Compensation ◽  
Arterial Ph ◽  
Oral Sodium ◽  
Ventilation Response

A steady state metabolic alkalosis was induced in two subjects over a period of several days utilizing oral sodium bicarbonate in dosages of 50 g/day. The purpose of inducing steady state metabolic alkalosis was to study the effects of such a state on the respiratory center responses to inspired gas mixtures, containing carbon dioxide, and to contrast these results with the control studies. The experiment was so designed that the arterial pH in both subjects tended to return toward normal in the presence of significant increases in blood bicarbonate. Repeated study of ventilation responses with room air and 4% and 6% carbon dioxide in inspired air revealed a definite and significant decrease in ventilation response to carbon dioxide during the periods of steady state alkalosis as compared to the control periods. Normal responses returned after some time lag. A consistent rise in paCOCO2 occurred with alkalosis, thus demonstrating respiratory compensation. In neither subject was total lung function or gas exchange affected by the alkalosis. The experiment was confirmed on several occasions with reproducible results. Note: (With the Research Assistance of Mary Di Lieto) Submitted on May 22, 1961

scholarly journals A New Control Technique of Percolated Structure of Polymer Blend Using Supercritical Carbon Dioxide.

1997 ◽  
Vol 6 (2) ◽  
pp. 115-119
Author(s):  
Mishima Kenji ◽  
Ezawa Masahisa ◽  
Enjouji Takashi ◽  
Oka Satoru ◽  
Matsuyama Kiyoshi ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Polymer Blend ◽  
Control Technique ◽  
Supercritical Carbon

Inhibition of carbonic anhydrase: its effect on carbon dioxide elimination by the lungs

1959 ◽  
Vol 14 (1) ◽  
pp. 109-115 ◽  
Author(s):  
John C. Mithoefer
Keyword(s):  
Carbon Dioxide ◽  
Steady State ◽  
Carbonic Anhydrase ◽  
Normal Animal ◽  
Carbon Dioxide Elimination ◽  
Carbonic Anhydrase Inhibition ◽  
Experimental Approaches

The effect of carbonic anhydrase inhibition on carbon dioxide elimination by the lungs has been studied in dogs by the following four experimental approaches: 1) the alveolar pathway (PaOO2 and PaCOCO2) was measured during the hyperventilation which follows carbonic anhydrase inhibition and compared to the normal pathway at the same hyperventilation. 2) The alveolar gas tensions were measured following carbonic anhydrase inhibition when the ventilation was held constant. 3) The changes in PaCOCO2 were measured when the ventilation was suddenly, artificially changed to a new level in the presence of carbonic anhydrase inhibition and in normal animals. 4) The CO2 output was measured directly during the hyperventilation which results from carbonic anhydrase inhibition, during the same hyperventilation in the normal animal and following carbonic anhydrase inhibition when the ventilation is held constant. These experiments demonstrate an immediate fall in CO2 output relative to the ventilation when carbonic anhydrase is inhibited, resulting in CO2 retention until a new steady state has been reached. An hypothesis is presented to explain the effect of carbonic anhydrase inhibition on CO2 transport. Submitted on March 28, 1958

Tissue carbon dioxide stores: magnitude of acute change in the dog

1964 ◽  
Vol 206 (4) ◽  
pp. 887-890 ◽  
Author(s):  
S. F. Sullivan ◽  
R. W. Patterson ◽  
E. M. Papper
Keyword(s):  
Carbon Dioxide ◽  
Steady State ◽  
Dissociation Constant ◽  
Average Rate ◽  
Carbon Dioxide Tension ◽  
Whole Body ◽  
Limiting Factor ◽  
Acute Change ◽  
Washout Curves ◽  
Mixed Venous

Carbon dioxide washout curves were determined in hyperventilated dogs. Direct measurement of mixed venous carbon dioxide tension allowed calculation of changes in whole-body CO2 stores. The average whole-body CO2 dissociation constant in ten studies was 3.73 ml/kg mm. The limiting factor in reaching a new steady-state value was represented by a slow compartment in the washout curve. The average rate constant for this compartment was 0.062 min–1. The slowest compartment in this analysis has a 98% change in 1 hr, therefore the experimentally determined whole-body dissociation constant should closely approximate actual changes in tissue CO2 stores, excluding bone and fat.

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