scholarly journals Establishing Trypanosoma cruzi farnesyl pyrophosphate synthase as a viable target for biosensor driven fragment‐based lead discovery

2020 ◽  
Vol 29 (4) ◽  
pp. 977-989 ◽  
Author(s):  
Giulia Opassi ◽  
Helena Nordström ◽  
Arne Lundin ◽  
Valeria Napolitano ◽  
Francesca Magari ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Farnesyl Pyrophosphate ◽  
Lead Discovery ◽  
Farnesyl Pyrophosphate Synthase

Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase

2003 ◽  
Vol 13 (19) ◽  
pp. 3231-3235 ◽  
Author(s):  
Sergio H. Szajnman ◽  
Andrea Montalvetti ◽  
Youhong Wang ◽  
Roberto Docampo ◽  
Juan B. Rodriguez
Keyword(s):  
Fatty Acids ◽  
Trypanosoma Cruzi ◽  
Farnesyl Pyrophosphate ◽  
Farnesyl Pyrophosphate Synthase

scholarly journals Virtual Screening for the Selection of New Candidates to Trypanosoma cruzi Farnesyl Pyrophosphate Synthase Inhibitors

2018 ◽  
Author(s):  
Larissa Oliveira ◽  
Janay Araújo ◽  
David Costa Júnior ◽  
Manoelito dos Santos Junior ◽  
Aníbal Santos Júnior ◽  
...  
Keyword(s):  
Virtual Screening ◽  
Trypanosoma Cruzi ◽  
Farnesyl Pyrophosphate ◽  
Farnesyl Pyrophosphate Synthase ◽  
Selection Of

Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi

2004 ◽  
Vol 23 (3) ◽  
pp. 273-285 ◽  
Author(s):  
Luciana R. Garzoni ◽  
Aura Caldera ◽  
Maria de Nazareth L. Meirelles ◽  
Solange L.de Castro ◽  
Roberto Docampo ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Farnesyl Pyrophosphate ◽  
Farnesyl Pyrophosphate Synthase ◽  
In Vitro Effects ◽  
Synthase Inhibitor

Cloning and characterization of Farnesyl pyrophosphate synthase gene from Anoectochilus

2019 ◽  
Vol 52 (3) ◽  
Author(s):  
Lin Yang ◽  
Jun Cheng Zhang ◽  
Wan Chen Li ◽  
Jing Tao Qu ◽  
Hao Qiang Yu ◽  
...  
Keyword(s):  
Farnesyl Pyrophosphate ◽  
Farnesyl Pyrophosphate Synthase

scholarly journals Antitrypanosomal Lead Discovery: Identification of a Ligand-Efficient Inhibitor of Trypanosoma cruzi CYP51 and Parasite Growth

2013 ◽  
Vol 56 (6) ◽  
pp. 2556-2567 ◽  
Author(s):  
Grasiella Andriani ◽  
Emanuele Amata ◽  
Joel Beatty ◽  
Zeke Clements ◽  
Brian J. Coffey ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Parasite Growth ◽  
Lead Discovery ◽  
Efficient Inhibitor
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