The impact of the extent and location of positive surgical margins on the risk of biochemical recurrence following radical prostatectomy in men with Gleason 7 prostate cancers

The Prostate ◽  
2021 ◽  
Author(s):  
Bashar Matti ◽  
Fairleigh Reeves ◽  
Matthew Prouse ◽  
Kamran Zargar‐Shoshtari
Keyword(s):  
Radical Prostatectomy ◽  
Biochemical Recurrence ◽  
Surgical Margins ◽  
Positive Surgical Margins ◽  
Prostate Cancers ◽  
The Impact

206: The Impact of Radical Prostatectomy Positive Surgical Margins on Fear of Cancer Recurrence: Results from Capsure

2007 ◽  
Vol 177 (4S) ◽  
pp. 69-70
Author(s):  
Y. Mark Hong ◽  
Jim C. Hu ◽  
Alan T. Paciorek ◽  
Sara J. Knight ◽  
Peter R. Carroll
Keyword(s):  
Radical Prostatectomy ◽  
Cancer Recurrence ◽  
Surgical Margins ◽  
Fear Of Cancer Recurrence ◽  
Positive Surgical Margins ◽  
Fear Of Cancer ◽  
The Impact

scholarly journals Do Positive Surgical Margins Predict Biochemical Recurrence in All Patients Without Adjuvant Therapy After Radical Prostatectomy?

2013 ◽  
Vol 54 (8) ◽  
pp. 510 ◽  
Author(s):  
Jun Woo Lee ◽  
Jae Hyun Ryu ◽  
Yun Beom Kim ◽  
Seung Ok Yang ◽  
Jeong Kee Lee ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Adjuvant Therapy ◽  
Biochemical Recurrence ◽  
Surgical Margins ◽  
Positive Surgical Margins

Length of site-specific positive surgical margins as a risk factor for biochemical recurrence following radical prostatectomy

2011 ◽  
Vol 18 (4) ◽  
pp. 272-279 ◽  
Author(s):  
Mark Hsu ◽  
Steven L Chang ◽  
Michelle Ferrari ◽  
Rosalie Nolley ◽  
Joseph C Presti Jr ◽  
...  
Keyword(s):  
Risk Factor ◽  
Radical Prostatectomy ◽  
Biochemical Recurrence ◽  
Surgical Margins ◽  
Site Specific ◽  
Positive Surgical Margins

Defining predictors of early, intermediate, and late biochemical recurrence in men with clinically localized prostate cancer treated with minimally invasive radical prostatectomy.

2017 ◽  
Vol 35 (6_suppl) ◽  
pp. 113-113
Author(s):  
Silvia Garcia Barreras ◽  
Igor Nunes-Silva ◽  
Rafael Sanchez-Salas ◽  
Fernando P. Secin ◽  
Victor Srougi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Logistic Regression ◽  
Lymph Node ◽  
Laparoscopic Surgery ◽  
Radical Prostatectomy ◽  
Minimally Invasive ◽  
Biochemical Recurrence ◽  
Surgical Margins ◽  
Positive Surgical Margins

113 Background: Follow up after radical prostatectomy should be tailored to clinical and pathologic characteristics. To determine predictive factors for early, intermediate and late biochemical recurrence (BCR) after minimally invasive radical prostatectomy (MIRP: lap and robot) in patients with localized prostate cancer (PCa). Methods: Prospective clinical, pathologic, and outcome data were collected for 6195 patients with cT1-3N0M0 PCa treated with MIRP at our institution from 2000 to 2016. None of them received neoadjuvant therapy. BCR was defined as PSA level greater than 0.2 ng/ml. Time to BCR was divided in terciles to identify variables associated with early ( < 12 months), intermediate (12-36 months) and late BCR ( > 36 months). Comparisons among groups were performed using ANOVA or Chi square test. Logistic regression models were built to determine risk factors associated with BCR at each time interval. Results: We identified 1148 (19%) patients with BCR. Median time to BCR was 24 months. Statistically significant differences were found between the groups concerning PSA preoperative, D’Amico risk, type of surgery, pT stage, pathological Gleason, positive margins and extracapsular extension. Multivariable logistic regression analysis showed preoperative PSA, positive nodes, positive surgical margins and laparoscopic surgery were associated with early BCR. Laparoscopic surgery was the only risk factor associated with intermediate term BCR. Significant predictors of late BCR included Gleason ≥ 7, ≥ pT3, positive surgical margins, lymph node dissection performance and laparoscopic surgery. Conclusions: Patients with high risk features like Gleason ≥ 7, ≥ pT3 and or positive surgical margins may develop late recurrence and deserve long term follow up. Identify patients with higher PSA and lymph node invasion has an important predictive role due to the risk of BCR within the first year. The association between laparoscopic technique and late BCR deserves further evaluation.

scholarly journals Risk Stratification for Biochemical Recurrence in Men With Positive Surgical Margins or Extracapsular Disease After Radical Prostatectomy: Results From the SEARCH Database

2008 ◽  
Vol 179 (5) ◽  
pp. 1791-1796 ◽  
Author(s):  
Jayakrishnan Jayachandran ◽  
Lionel L. Bañez ◽  
Donna E. Levy ◽  
William J. Aronson ◽  
Martha K. Terris ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Risk Stratification ◽  
Biochemical Recurrence ◽  
Surgical Margins ◽  
Positive Surgical Margins
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