scholarly journals The ring size of monocyclic ET‐1 controls selectivity and signaling efficiency at both endothelin receptor subtypes

2021 ◽  
Author(s):  
Philipp Wolf ◽  
Annette G. Beck‐Sickinger
Keyword(s):  
Receptor Subtypes ◽  
Ring Size ◽  
Endothelin Receptor ◽  
Signaling Efficiency

Significance of Endothelin Receptor Subtypes in the Kidneys of Spontaneously Hypertensive Rats

1995 ◽  
Vol 26 ◽  
pp. S470-472
Author(s):  
Berthold Hocher ◽  
Peter Rohmeiss ◽  
Rüdiger Zart ◽  
Fritz Diekmann ◽  
Volker Vogt ◽  
...  
Keyword(s):  
Spontaneously Hypertensive Rats ◽  
Receptor Subtypes ◽  
Endothelin Receptor ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive

Localization and Distribution of Endothelin Receptor Subtypes in Pulmonary Vasculature of Normal and Hypoxia-Exposed Rats

1999 ◽  
Vol 20 (4) ◽  
pp. 620-630 ◽  
Author(s):  
Sanae Soma ◽  
Hideki Takahashi ◽  
Masashi Muramatsu ◽  
Masahiko Oka ◽  
Yoshinosuke Fukuchi
Keyword(s):  
Pulmonary Vasculature ◽  
Receptor Subtypes ◽  
Endothelin Receptor

CELLULAR LOCALIZATION OF ENDOTHELIN RECEPTOR SUBTYPES IN THE RAT KIDNEY FOLLOWING IN VITRO LABELLING

1996 ◽  
Vol 23 (6-7) ◽  
pp. 524-531 ◽  
Author(s):  
Rachael Dean ◽  
Jialong Zhuo ◽  
Daine Alcorn ◽  
David Casley ◽  
Frederick AO Mendelsohn
Keyword(s):  
Cellular Localization ◽  
Rat Kidney ◽  
Receptor Subtypes ◽  
Endothelin Receptor

Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ET-1

1992 ◽  
Vol 182 (1) ◽  
pp. 144-150 ◽  
Author(s):  
Kyoko Nakamichi ◽  
Masaki Ihara ◽  
Masahiko Kobayashi ◽  
Toshihiko Saeki ◽  
Kiyofumi Ishikawa ◽  
...  
Keyword(s):  
Receptor Subtypes ◽  
The Novel ◽  
Endothelin Receptor ◽  
Selective Ligands

Pharmacologic Evidence for the Presence of Three Functional Endothelin Receptor Subtypes in Rabbit Saphenous Vein

1995 ◽  
Vol 26 ◽  
pp. S163-168 ◽  
Author(s):  
Stephen A. Douglas ◽  
George R. Beck ◽  
John D. Elliott ◽  
Eliot H. Ohlstein
Keyword(s):  
Saphenous Vein ◽  
Receptor Subtypes ◽  
Endothelin Receptor

Endothelin receptor antagonists: a brief review

1994 ◽  
Vol 72 (11) ◽  
pp. 1469-1471 ◽  
Author(s):  
Suzanne Moreland
Keyword(s):  
Smooth Muscle ◽  
Receptor Antagonist ◽  
Receptor Subtypes ◽  
Endothelin Receptor Antagonists ◽  
Endothelin Receptor ◽  
Receptor Antagonists ◽  
Vascular Activity ◽  
Vasodilatory Activity ◽  
Healthy Control ◽  
Circulating Levels

The endothelins are a family of potent vasoconstrictors, some of which also have vasodilatory activity. In many diseases associated with tissue hypoxia or ischemia and in diseases in which vasoconstriction plays a role, the circulating levels of endothelin are higher than in healthy, control subjects. These findings stimulated research aimed at discovering endothelin receptor antagonists. This review focuses on the binding potency and vascular activity of these new peptide and nonpeptide endothelin receptor antagonists.Key words: endothelin, endothelin receptor subtypes, vascular smooth muscle, endothelin receptor antagonist.

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