Characterization of metabolites of a novel histamine H2-receptor antagonist, lafutidine, in human liver microsomes by liquid chromatography coupled with ion trap mass spectrometry

Yuya Wang; Xiaoyan Chen; Qiang Li; Dafang Zhong

doi:10.1002/rcm.3558

Characterization of metabolites of a novel histamine H2-receptor antagonist, lafutidine, in human liver microsomes by liquid chromatography coupled with ion trap mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3558 ◽

2008 ◽

Vol 22 (12) ◽

pp. 1843-1852 ◽

Cited By ~ 7

Author(s):

Yuya Wang ◽

Xiaoyan Chen ◽

Qiang Li ◽

Dafang Zhong

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Human Liver ◽

Ion Trap ◽

Liver Microsomes ◽

Ion Trap Mass Spectrometry ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

Histamine H2 Receptor Antagonist

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Characterization of metabolism of (+)-praeruptorin B and (+)-praeruptorin E in human and rat liver microsomes by liquid chromatography coupled with ion trap mass spectrometry and time-of-flight mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.4922 ◽

2011 ◽

Vol 25 (6) ◽

pp. 719-730 ◽

Cited By ~ 18

Author(s):

Yue-Lin Song ◽

Ru Yan ◽

Wang-Hui Jing ◽

Hai-Yu Zhao ◽

Yi-Tao Wang

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Rat Liver ◽

Ion Trap ◽

Liver Microsomes ◽

Time Of Flight ◽

Ion Trap Mass Spectrometry ◽

Rat Liver Microsomes ◽

Flight Mass Spectrometry

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In vitro metabolism of corydaline in human liver microsomes and hepatocytes using liquid chromatography-ion trap mass spectrometry

Journal of Separation Science ◽

10.1002/jssc.201101094 ◽

2012 ◽

Vol 35 (9) ◽

pp. 1102-1109 ◽

Cited By ~ 9

Author(s):

Hye Young Ji ◽

Hyeri Lee ◽

Jeong-Han Kim ◽

Ki Hyun Kim ◽

Kang Ro Lee ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Human Liver ◽

Ion Trap ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

In Vitro Metabolism ◽

Ion Trap Mass Spectrometry

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Application of liquid chromatography–electrospray ionization-ion trap mass spectrometry to investigate the metabolism of silibinin in human liver microsomes

Journal of Chromatography B ◽

10.1016/s1570-0232(03)00484-7 ◽

2003 ◽

Vol 794 (2) ◽

pp. 303-310 ◽

Cited By ~ 17

Author(s):

Chandrani Gunaratna ◽

Tianyi Zhang

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Human Liver ◽

Ion Trap ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Ion Trap Mass Spectrometry

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Characterization of xylazine metabolism in rat liver microsomes using liquid chromatography-hybrid triple quadrupole-linear ion trap-mass spectrometry

Biomedical Chromatography ◽

10.1002/bmc.2875 ◽

2013 ◽

Vol 27 (7) ◽

pp. 882-888 ◽

Cited By ~ 13

Author(s):

David St-Germain Lavoie ◽

Floriane Pailleux ◽

Pascal Vachon ◽

Francis Beaudry

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Trap ◽

Liver Microsomes ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Rat Liver Microsomes ◽

Triple Quadrupole ◽

Quadrupole Linear Ion Trap

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Simultaneous measurement of metabolic stability and metabolite identification of 7-methoxymethylthiazolo[3,2-a]pyrimidin-5-one derivatives in human liver microsomes using liquid chromatography/ion-trap mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.1891 ◽

2005 ◽

Vol 19 (8) ◽

pp. 1069-1074 ◽

Cited By ~ 10

Author(s):

E. Kantharaj ◽

Peter B. Ehmer ◽

An Tuytelaars ◽

Anne Van Vlaslaer ◽

Claire Mackie ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Simultaneous Measurement ◽

Human Liver ◽

Ion Trap ◽

Liver Microsomes ◽

Metabolite Identification ◽

Human Liver Microsomes ◽

Metabolic Stability ◽

Ion Trap Mass Spectrometry

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Application of liquid chromatography/ion trap mass spectrometry to the characterization of the related substances of clarithromycin

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.2704 ◽

2006 ◽

Vol 20 (20) ◽

pp. 3101-3110 ◽

Cited By ~ 13

Author(s):

Stefanie Leonard ◽

Monica Ferraro ◽

Erwin Adams ◽

Jos Hoogmartens ◽

Ann Van Schepdael

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Trap ◽

Ion Trap Mass Spectrometry ◽

Related Substances

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High performance liquid chromatography combined with electrospray ionization ion trap mass spectrometry in the characterization of (methoxymethyl)melamine resins

Rapid Communications in Mass Spectrometry ◽

10.1002/(sici)1097-0231(199708)11:12<1321::aid-rcm965>3.0.co;2-q ◽

1997 ◽

Vol 11 (12) ◽

pp. 1321-1328 ◽

Cited By ~ 16

Author(s):

Adriano Marcelli ◽

Donata Favretto ◽

Pietro Traldi

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

High Performance ◽

Ion Trap ◽

Ion Trap Mass Spectrometry

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Rapid Detection and Structural Characterization of Methysticin Metabolites Generated from Rat and Human Liver Microsomes and Hepatocytes by Ultra‐high Performance Liquid Chromatography Coupled with High‐resolution Mass Spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.9208 ◽

2021 ◽

Author(s):

Adila Tuerxuntayi ◽

Abudourusuli Tusun ◽

Abulikemu Tajiguli

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Rapid Detection ◽

Human Liver ◽

High Performance ◽

High Resolution Mass Spectrometry ◽

Liver Microsomes ◽

Resolution Mass

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In vitro metabolites characterization of ponatinib in human liver microsomes using ultra‐high performance liquid chromatography combined with Q‐Exactive‐Orbitrap tandem mass spectrometry

Biomedical Chromatography ◽

10.1002/bmc.4819 ◽

2020 ◽

Vol 34 (6) ◽

Author(s):

Lei Gao ◽

Qiqi Xu ◽

Qingqing Liu ◽

Xiuzhuang Lang

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Tandem Mass ◽

Q Exactive

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Characterization of metabolites of sibutramine in primary cultures of rat hepatocytes by liquid chromatography–ion trap mass spectrometry

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-008-2540-8 ◽

2008 ◽

Vol 393 (4) ◽

pp. 1327-1336 ◽

Cited By ~ 12

Author(s):

Kati S. Hakala ◽

Marek Link ◽

Barbora Szotakova ◽

Lenka Skalova ◽

Risto Kostiainen ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Trap ◽

Primary Cultures ◽

Rat Hepatocytes ◽

Ion Trap Mass Spectrometry

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