Long-term results of quality of life after standard laparoscopic vs. robot-assisted laparoscopic fundoplications for gastro-oesophageal reflux disease. A comparative clinical trial

2009 ◽  
Vol 5 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Jens Hartmann ◽  
Charalambos Menenakos ◽  
Juergen Ordemann ◽  
Marc Nocon ◽  
Wieland Raue ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Reflux Disease ◽  
Oesophageal Reflux ◽  
Long Term Results ◽  
Robot Assisted ◽  
Comparative Clinical Trial ◽  
Oesophageal Reflux Disease

scholarly journals P-BN52 Patient-reported outcome measures following fundoplication – lind and nissens - single centre, single surgeon results

2021 ◽  
Vol 108 (Supplement_9) ◽  
Author(s):  
Anitha Muthusami ◽  
Sindoora Jayaprakash ◽  
Akash Jangan ◽  
Chaminda Sellahewa ◽  
Akinfemi Akingboye
Keyword(s):  
Quality Of Life ◽  
Hernia Repair ◽  
Hiatus Hernia ◽  
Reflux Disease ◽  
Oesophageal Reflux ◽  
Symptom Improvement ◽  
Oesophageal Reflux Disease ◽  
The Impact

Abstract Background Gastro-oesophageal reflux disease (GORD) affects approximately 10%-20% of adults in Western Countries. Surgery is indicated following failed medical therapy. This is recommended when GORD symptoms have a significant impact on the quality of life (QOL). A long term follow up is critical to authenticate outcomes following anti-reflux/hiatal hernia repair surgery. Objective information must be linked to the patient’s perception of the disease and the impact on the QOL. Our survey aims assess the long term patient’s satisfaction and the impact on QOL following standard Nissen’s and Lind’s fundoplication for GORD. Methods A single surgeon’s prospective database of laparoscopic and or open hiatus hernia repair and fundoplication with patient’s demographics since 2014 in a district general hospital was analyzed. These patients were contacted virtually between June and July 2021. Verbal consent was obtained,  the patients were asked to answer questions from the GERD HRQL (AUGIS modified for use in National Hiatal Surgery Registry) for Hiatus Hernia (HH) or Gastro-oesophageal reflux disease (GORD) or both to assess postoperative symptoms relief, complications, and overall quality of life. The scoring scale was divided into two categories; no symptoms or mild–moderate symptom improvement and those with significant symptoms. Results Of the 93 patients, 85 (91.4%) underwent primary laparoscopic repair with 91 cases performed as elective procedure. 68 patients (73%) underwent a Lind wrap, 24 (26%) had a floppy Nissen’s and one was a dor procedure. Three patients with unrelated death were excluded from the analysis. We had 67 responders (74.4%), 56 answered the GORD questionnaire and 66 responded to the HH questionnaire.  84% patients with GORD and 85% of patients with HH had significant symptom improvement. 61 % and 55% suffered from significant gas bloat symptoms in each group. As for dysphagia; 77% had no - mild dysphagia and 23% had significant dysphagia and this was 79% and 21% in HH group.  Conclusions Overall patients satisfaction and improvement in quality of life was 90% . Half of our patient experienced gas bloat syndrome, which had little effect on their quality of life. 20% had long term dysphagia and one third of the patients seem to continue to use PPI despite expressing a satisfactory clinical improvement. It appears that patient’s long term improvement on  the   quality of life was satisfactory from both Nissen’s and Lind procedure.

scholarly journals Acupuncture for refractory gastro-oesophageal reflux disease: a systematic review and meta-analysis protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e030713 ◽  
Author(s):  
Dacheng Li ◽  
Li Zhu ◽  
Daming Liu
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Adverse Events ◽  
Reflux Disease ◽  
Meta Analysis ◽  
Oesophageal Reflux ◽  
Cochrane Central Register ◽  
Efficacy And Safety ◽  
Oesophageal Reflux Disease

IntroductionRefractory gastro-oesophageal reflux disease (rGORD) is a common disease, affecting patients’ quality of life. Since conventional medicines have limitations, like low effective rates and adverse events, acupuncture may be a promising therapy for rGORD. While no related systematic review has been published, the present study is designed to evaluate the efficacy and safety of acupuncture for rGORD.Methods and analysisPubMed, the Cochrane Central Register of Controlled Trials and Chinese electronic databases, including China National Knowledge Infrastructure, Wan Fang database, VIP, SinoMed and the Chinese Clinical Trial Registry, will be searched from establishment of the database to 31 August 2019. There will be no limitations on language, and all articles will be screened and collected by two reviewers independently. RevMan V.5.3.5 software will be used for meta-analysis, and the conduction of study will refer to the Cochrane Handbook for Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocol guidelines. The efficacy and safety of acupuncture for rGORD will be evaluated based on outcomes, including global symptom improvement, oesophageal sphincter function test measured by high-resolution manometry, quality of life, recurrence rate and adverse events.Ethics and disseminationThere is no necessity for this study to acquire an ethical approval, and this review will be disseminated in a peer-reviewed journal or conference presentation.Trial registration numberCRD42018111912.

Quality of life in gastro-oesophageal reflux disease

2001 ◽  
Vol 33 (9) ◽  
pp. 737-739 ◽  
Author(s):  
T. Kamolz ◽  
V. Velanovich
Keyword(s):  
Quality Of Life ◽  
Reflux Disease ◽  
Oesophageal Reflux ◽  
Oesophageal Reflux Disease

The development of a new measure of quality of life in the management of gastro-oesophageal reflux disease: the Reflux questionnaire

2006 ◽  
Vol 16 (2) ◽  
pp. 331-343 ◽  
Author(s):  
Susan Macran ◽  
Samantha Wileman ◽  
Garry Barton ◽  
Ian Russell ◽  
Keyword(s):  
Quality Of Life ◽  
Reflux Disease ◽  
Oesophageal Reflux ◽  
Oesophageal Reflux Disease

scholarly journals Evaluating the Long-Term Efficacy of Acupuncture Therapy for Subacute Poststroke Aphasia: Study Protocol for a Randomized, Blinded, Controlled, Multicentre Trial

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Xiaolin Li ◽  
Ying Gao ◽  
Chi Zhang ◽  
Qingsu Zhang ◽  
Xiyan Xin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Acupuncture Therapy ◽  
Long Term Results ◽  
Control Group ◽  
Acupuncture Points ◽  
Term Efficacy ◽  
Secondary Outcomes

Background. Poststroke aphasia (PSA) is a disabling condition that decreases the quality of life, and the duration of the disease harms the quality of life of PSA patients. Acupuncture has been widely employed for PSA. There is some evidence for the immediate treatment efficacy of acupuncture for PSA; however, long-term results after acupuncture may be poorer. Methods. This is a multicentre, randomized, blinded, nonacupoint (NA) acupuncture controlled, multimodal neuroimaging clinical trial. A total of 48 subjects with subacute PSA will be randomly assigned to an acupoint group or an NA control group. The acupoint group will receive acupuncture with normal needling at DU20, EX-HN1, HT5, GB39, EX-HN12, EX-HN13, and CV23. The NA control group will receive acupuncture in locations not corresponding to acupuncture points as sham acupoints. Both groups will receive identical speech and language therapy thrice a week for four weeks. The primary outcome will be the change in the aphasia quotient (AQ) score measured by the Western Aphasia Battery (WAB) test during the 12th week after randomization. Participants will be blindly assessed at prerandomization (baseline) and 4 weeks, 12 weeks, and 24 weeks after randomization. The secondary outcomes include the Boston Diagnostic Aphasia Examination (BDAE) score, the Disease Prognosis Scale score for ischaemic stroke, etc. Magnetic resonance imaging (MRI) and electroencephalogram (EEG) will also be performed at 4-time intervals as secondary outcomes. All scores and image evaluations will be taken at the same point as the linguistic evaluation. The multilevel evaluation technique will be used to assess the long-term efficacy of acupuncture therapy. MRI scans and EEG will be used to assess acupuncture-related neuroplasticity changes. Discussion. The results from our trial will help to supply evidence for the long-term acupuncture effects for PSA over a long follow-up period. It will provide valuable information for future studies in the field of PSA treatment. The trial was registered at the Chinese Clinical Trial Registry on 16 March 2020 (ChiCTR2000030879).

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