FNAOSiPPEA
            [
            ]
            /Zn(II) as a Bifunctional Lewis Acid/ Bronsted Base Heterogeneous Magnetic Nanocatalyst Based on Nano‐Almond Shell for Synthesis of Naphtho[1,3]oxazine Derivatives**

Highly enantioselective formal [3+2] cycloaddition of N-2,2,2-trifluoroethylisatin ketimines with aurone derivatives of low reactivity by chiral dinuclear zinc catalysts has been developed via a Brønsted base and Lewis acid cooperative...

Download Full-text

Dinuclear zinc-catalyzed asymmetric [3+2] cyclization reaction for direct assembly of chiral α-amino-γ-butyrolactones bearing three stereocenters

Organic Chemistry Frontiers ◽

10.1039/d1qo01338f ◽

2021 ◽

Author(s):

Wen-Peng Yang ◽

Shi-Kun Jia ◽

Tian-Tian Liu ◽

Yuan-Zhao Hua ◽

Mincan Wang

Keyword(s):

Lewis Acid ◽

Cyclization Reaction ◽

Activation Model ◽

Direct Assembly ◽

Brønsted Base ◽

Cooperative Activation

An efficient enantioselective [3+2] cyclization reaction of α-hydroxy-1-indanones and alkylidene azlactones has been developed with chiral dinuclear zinc catalysts via a Brønsted base and Lewis acid cooperative activation model. This...

Download Full-text

Highly effective Brønsted base/lewis acid cooperative catalysis: a new Cd metal–organic framework for the synthesis of Hantzsch 1,4-DHPs at ambient temperature

New Journal of Chemistry ◽

10.1039/c7nj01509g ◽

2017 ◽

Vol 41 (24) ◽

pp. 15475-15484 ◽

Cited By ~ 17

Author(s):

Farzaneh Rouhani ◽

Ali Morsali

Keyword(s):

Ambient Temperature ◽

Lewis Acid ◽

Functional Group ◽

Metal Organic Framework ◽

Cooperative Catalysis ◽

Highly Effective ◽

Metal Organic ◽

Brønsted Base ◽

Organic Framework

A new 3D metal–organic framework {[Cd3(BDC)3(OPP)(DMF)2]·2DMA}n (TMU-33) has been synthesized. The performance of the imine functional group of the OPP ligand as a Brønsted base and open Cd site as a Lewis acid in this framework was investigated as cooperative catalyst.

Download Full-text

Cyanation ofN-Acylhydrazones with Trimethylsilyl Cyanide Promoted by a Brønsted Base and a Lewis Acid

Advanced Synthesis & Catalysis ◽

10.1002/adsc.200505272 ◽

2005 ◽

Vol 347 (15) ◽

pp. 1899-1903 ◽

Cited By ~ 4

Author(s):

Hideyuki Konishi ◽

Chikako Ogawa ◽

Masaharu Sugiura ◽

Shū Kobayashi

Keyword(s):

Lewis Acid ◽

Trimethylsilyl Cyanide ◽

Brønsted Base

Download Full-text

Synthesis of novel carbohydrate mimetics via 1,2-oxazines

Pure and Applied Chemistry ◽

10.1351/pac-con-11-09-20 ◽

2011 ◽

Vol 84 (1) ◽

pp. 23-36 ◽

Cited By ~ 32

Author(s):

Léa Bouché ◽

Hans-Ulrich Reissig

Keyword(s):

Lewis Acid ◽

Good Yield ◽

Biological Activities ◽

Amino Sugar ◽

Sugar Alcohols ◽

Bicyclic Compounds ◽

Efficient Route ◽

Oxazine Derivatives

The combination of lithiated alkoxyallenes with carbohydrate-derived nitrones constitutes a flexible entry to highly functionalized enantiopure 1,2-oxazine derivatives. They can be used as precursors for acyclic and cyclic carbohydrate-like products such as amino sugar alcohols, azetidine and pyrrolidine derivatives. The Lewis acid-promoted rearrangement of 1,3-dioxolanyl-substituted 1,2-oxazines to bicyclic compounds allows an efficient route to novel amino pyran and oxepane derivatives. After subsequent transformations, new carbohydrate mimetics or “real” carbohydrates were obtained in good yield and often in a stereodivergent fashion. These compounds have already been employed for the preparation of unusual di- and trisaccharide derivatives. Several of the products prepared showed interesting biological activities, e.g., as L- and P-selectin inhibitors with IC50 values in the subnanomolar range.

Download Full-text