scholarly journals Induction of Primordial Germ Cell-Like Cells From Mouse Embryonic Stem Cells by ERK Signal Inhibition

Stem Cells ◽  
2014 ◽  
Vol 32 (10) ◽  
pp. 2668-2678 ◽  
Author(s):  
Tohru Kimura ◽  
Yoshiaki Kaga ◽  
Hiroshi Ohta ◽  
Mika Odamoto ◽  
Yoichi Sekita ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells

Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation

2010 ◽  
Vol 392 (3) ◽  
pp. 311-316 ◽  
Author(s):  
Noriko Yamano ◽  
Tohru Kimura ◽  
Shoko Watanabe-Kushima ◽  
Takashi Shinohara ◽  
Toru Nakano
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Akt Activation

SET domain-containing protein 5 is required for expression of primordial germ cell specification-associated genes in murine embryonic stem cells

2017 ◽  
Vol 35 (5) ◽  
pp. 247-253 ◽  
Author(s):  
Seung Eun Yu ◽  
Min Seong Kim ◽  
Su Hyung Park ◽  
Byong Chul Yoo ◽  
Kyung Hee Kim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Embryonic Stem ◽  
Set Domain ◽  
Cell Specification ◽  
Murine Embryonic Stem Cells ◽  
Germ Cell Specification

Primordial germ cell differentiation of nuclear transfer embryonic stem cells using surface modified electroconductive scaffolds

2016 ◽  
Vol 53 (4) ◽  
pp. 371-380
Author(s):  
Tarlan Eslami-Arshaghi ◽  
Saeid Vakilian ◽  
Ehsan Seyedjafari ◽  
Abdolreza Ardeshirylajimi ◽  
Masoud Soleimani ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cell Differentiation ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Nuclear Transfer ◽  
Primordial Germ Cell ◽  
Embryonic Stem ◽  
Germ Cell Differentiation ◽  
Surface Modified

scholarly journals Post-meiotic male germ cell differentiation of mouse embryonic stem cells by exposure to conditioned medium

2019 ◽  
Vol 112 (3) ◽  
pp. e101-e102
Author(s):  
Aysha Trout ◽  
Philip Xie ◽  
Alessandra Parrella ◽  
Zev Rosenwaks ◽  
Gianpiero D. Palermo
Keyword(s):  
Stem Cells ◽  
Cell Differentiation ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Conditioned Medium ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Male Germ Cell ◽  
Germ Cell Differentiation

scholarly journals Primordial Germ Cell Specification from Embryonic Stem Cells

PLoS ONE ◽  
2008 ◽  
Vol 3 (12) ◽  
pp. e4013 ◽  
Author(s):  
Wei Wei ◽  
Tingting Qing ◽  
Xin Ye ◽  
Haisong Liu ◽  
Donghui Zhang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Embryonic Stem ◽  
Cell Specification ◽  
Germ Cell Specification

scholarly journals Haploid mouse germ cell precursors from embryonic stem cells reveal Xist activation from a single X chromosome

2020 ◽  
Author(s):  
Eishi Aizawa ◽  
Corinne Kaufmann ◽  
Sarah Sting ◽  
Remo Freimann ◽  
Anton Wutz
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
X Chromosome ◽  
Primordial Germ Cells ◽  
Primordial Germ Cell ◽  
Embryonic Stem ◽  
Haploid Genome ◽  
Blocking Factors

SummaryMammalian haploid cells have applications for genetic screening and substituting gametic genomes. Here we characterize a culture system for obtaining haploid primordial germ cell-like cells (PCGLCs) from haploid mouse embryonic stem cells (ESCs). We find that a haploid genome is maintained in PGCLCs with a high frequency indicating a substantially lower rate of diploidization than somatic cells. Characterization of the differentiating haploid ESCs reveals that Xist is activated from the single X chromosome. This observation suggests that X chromosome inactivation is initiated in haploid cells consistent with a model where autosomal blocking factors set a threshold for X-linked activators. The germline segregates from the epiblast and differs from somatic lineages in gene expression and epigenetic mechanisms. The ability of primordial germ cells for repressing Xist might contribute to the maintenance of a haploid genome.

scholarly journals Max is a repressor of germ cell-related gene expression in mouse embryonic stem cells

2013 ◽  
Vol 4 (1) ◽  
Author(s):  
Ikuma Maeda ◽  
Daiji Okamura ◽  
Yuko Tokitake ◽  
Makiko Ikeda ◽  
Hiroko Kawaguchi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Related Gene

Germ cell differentiation of mouse embryonic stem cells can be influenced by the culture medium

2019 ◽  
Vol 95 (3) ◽  
pp. 210-218
Author(s):  
Soghra Bahmanpour ◽  
Tahereh Talaei Khozani ◽  
Azam Soleimani ◽  
Nehleh Zareifard
Keyword(s):  
Stem Cells ◽  
Cell Differentiation ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Culture Medium ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Germ Cell Differentiation

Germ-cell culture conditions facilitate the production of mouse embryonic stem cells

2014 ◽  
Vol 81 (9) ◽  
pp. 794-804
Author(s):  
Priscila Ramos-Ibeas ◽  
Eva Pericuesta ◽  
Raúl Fernández-González ◽  
Alfonso Gutiérrez-Adán ◽  
Miguel Ángel Ramírez
Keyword(s):  
Stem Cells ◽  
Cell Culture ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Culture Conditions ◽  
Cell Culture Conditions
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