scholarly journals Phosphodiesterase inhibitors roflumilast and vardenafil prevent sleep deprivation‐induced deficits in spatial pattern separation

Synapse ◽  
2020 ◽  
Vol 74 (6) ◽  
Author(s):  
Pim R. A. Heckman ◽  
Femke Roig Kuhn ◽  
Frank Raven ◽  
Youri G. Bolsius ◽  
Jos Prickaerts ◽  
...  
Keyword(s):  
Sleep Deprivation ◽  
Spatial Pattern ◽  
Phosphodiesterase Inhibitors ◽  
Pattern Separation ◽  
Spatial Pattern Separation

The Effect of Immature Neurons on Spatial Pattern Separation in Hippocampal Cultured Network

2019 ◽  
Vol 139 (7) ◽  
pp. 814-815
Author(s):  
Fumika Moriya ◽  
Kenta Shimba ◽  
Kiyoshi Kotani ◽  
Yasuhiko Jimbo
Keyword(s):  
Spatial Pattern ◽  
Pattern Separation ◽  
Immature Neurons ◽  
Spatial Pattern Separation

scholarly journals Spatial pattern separation in cognitively normal young and older adults

Hippocampus ◽  
2012 ◽  
Vol 22 (9) ◽  
pp. 1826-1832 ◽  
Author(s):  
Heather M. Holden ◽  
Calhuei Hoebel ◽  
Kelly Loftis ◽  
Paul E. Gilbert
Keyword(s):  
Older Adults ◽  
Spatial Pattern ◽  
Pattern Separation ◽  
Cognitively Normal ◽  
Spatial Pattern Separation

scholarly journals Memory for Spatial Location: Role of the Hippocampus in Mediating Spatial Pattern Separation

1998 ◽  
Vol 18 (2) ◽  
pp. 804-810 ◽  
Author(s):  
Paul E. Gilbert ◽  
Raymond P. Kesner ◽  
William E. DeCoteau
Keyword(s):  
Spatial Pattern ◽  
Spatial Location ◽  
Pattern Separation ◽  
Spatial Pattern Separation

[P1-471]: EFFECT OF ALZHEIMER's DISEASE ON SPATIAL PATTERN SEPARATION

2017 ◽  
Vol 13 (7S_Part_9) ◽  
pp. P469-P470
Author(s):  
Jan Laczó ◽  
Martina Parizkova ◽  
Hana Markova ◽  
Ross Andel ◽  
Martin Vyhnalek ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Spatial Pattern ◽  
Pattern Separation ◽  
Spatial Pattern Separation

Selective alteration of adult hippocampal neurogenesis and impaired spatial pattern separation performance in the RSK2-deficient mouse model of Coffin-Lowry syndrome

2018 ◽  
Vol 115 ◽  
pp. 69-81 ◽  
Author(s):  
Charlotte Castillon ◽  
Steeve Lunion ◽  
Nathalie Desvignes ◽  
André Hanauer ◽  
Serge Laroche ◽  
...  
Keyword(s):  
Mouse Model ◽  
Spatial Pattern ◽  
Hippocampal Neurogenesis ◽  
Adult Hippocampal Neurogenesis ◽  
Pattern Separation ◽  
Separation Performance ◽  
Deficient Mouse ◽  
Spatial Pattern Separation

scholarly journals Running enhances spatial pattern separation in mice

2010 ◽  
Vol 107 (5) ◽  
pp. 2367-2372 ◽  
Author(s):  
David J. Creer ◽  
Carola Romberg ◽  
Lisa M. Saksida ◽  
Henriette van Praag ◽  
Timothy J. Bussey
Keyword(s):  
Physical Activity ◽  
Spatial Pattern ◽  
Hippocampal Neurogenesis ◽  
Pattern Separation ◽  
Regular Exercise ◽  
Brain Health ◽  
Voluntary Running ◽  
Spatial Pattern Separation ◽  
Cell Genesis ◽  
Old Mice

Increasing evidence suggests that regular exercise improves brain health and promotes synaptic plasticity and hippocampal neurogenesis. Exercise improves learning, but specific mechanisms of information processing influenced by physical activity are unknown. Here, we report that voluntary running enhanced the ability of adult (3 months old) male C57BL/6 mice to discriminate between the locations of two adjacent identical stimuli. Improved spatial pattern separation in adult runners was tightly correlated with increased neurogenesis. In contrast, very aged (22 months old) mice had impaired spatial discrimination and low basal cell genesis that was refractory to running. These findings suggest that the addition of newly born neurons may bolster dentate gyrus-mediated encoding of fine spatial distinctions.

P4-019: Variability in Spatial Pattern Separation Performance in Memory Impaired and Unimpaired Older Adults

2010 ◽  
Vol 6 ◽  
pp. e26-e26
Author(s):  
Shauna M. Stark ◽  
Micheal A. Yassa ◽  
Craig E.L. Stark
Keyword(s):  
Older Adults ◽  
Spatial Pattern ◽  
Pattern Separation ◽  
Separation Performance ◽  
Spatial Pattern Separation

The influence of enrichment on spatial pattern separation in zebrafish (Danio rerio)

BIOS ◽  
2020 ◽  
Vol 91 (1) ◽  
pp. 31
Author(s):  
Cairsty DePasquale ◽  
Paul Armstrong ◽  
Xiaosong Li
Keyword(s):  
Spatial Pattern ◽  
Danio Rerio ◽  
Pattern Separation ◽  
Spatial Pattern Separation

The spontaneous location recognition task for assessing spatial pattern separation and memory across a delay in rats and mice

2021 ◽  
Author(s):  
Amy C. Reichelt ◽  
Cecilia P. Kramar ◽  
Olivia R. Ghosh-Swaby ◽  
Paul A. S. Sheppard ◽  
Brianne A. Kent ◽  
...  
Keyword(s):  
Spatial Pattern ◽  
Recognition Task ◽  
Pattern Separation ◽  
Location Recognition ◽  
Spatial Pattern Separation ◽  
Rats And Mice
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