miR ‐146a promotes proliferation, invasion, and epithelial‐to‐mesenchymal transition in oral squamous carcinoma cells

2020 ◽  
Vol 35 (10) ◽  
pp. 1050-1057
Author(s):  
Fan Wang ◽  
Li‐Jun Ye ◽  
Feng‐Juan Wang ◽  
Hong‐Fang Liu ◽  
Xiao‐Long Wang
Keyword(s):  
Epithelial To Mesenchymal Transition ◽  
Squamous Carcinoma ◽  
Carcinoma Cells ◽  
Mesenchymal Transition ◽  
Squamous Carcinoma Cells ◽  
Oral Squamous Carcinoma

scholarly journals Snail-dependent and -independent Epithelial-Mesenchymal Transition in Oral Squamous Carcinoma Cells

2006 ◽  
Vol 54 (11) ◽  
pp. 1263-1275 ◽  
Author(s):  
Minna Takkunen ◽  
Reidar Grenman ◽  
Mika Hukkanen ◽  
Matti Korhonen ◽  
Antonio García de Herreros ◽  
...  
Keyword(s):  
Epithelial Mesenchymal Transition ◽  
Squamous Carcinoma ◽  
Carcinoma Cells ◽  
Mesenchymal Transition ◽  
Squamous Carcinoma Cells ◽  
Oral Squamous Carcinoma

scholarly journals Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial–Mesenchymal Transition of Epithelial Cells

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Chun-ming Huang ◽  
Ting-lin Yan ◽  
Zhi Xu ◽  
Meng Wang ◽  
Xiao-cheng Zhou ◽  
...  
Keyword(s):  
Tumor Microenvironment ◽  
Epithelial Cells ◽  
Cell Surface ◽  
Cell Fusion ◽  
Squamous Carcinoma ◽  
Fusion Rate ◽  
Carcinoma Cells ◽  
Mesenchymal Transition ◽  
Squamous Carcinoma Cells ◽  
Oral Squamous Carcinoma

Increasing evidence and indications showed that cell fusion is crucial in tumor development and metastasis, and hypoxia, a closely linked factor to tumor microenvironment, which can lead to EMT, induces angiogenesis and metastasis in tumor growth. However, the relationship between hypoxia and fusion has not been reported yet. EMT will change some proteins in the epithelial cell surface and the changes of proteins in cell surface may increase cell fusion. This study found that hypoxia promotes the spontaneous cell fusion between Oral Squamous Carcinoma Cells (OSCCs) and Human Immortalized Oral Epithelial Cells (HIOECs). At the same time, Hypoxia can lead to EMT, and hypoxia-pretreated HIOECs increased fusion rate with OSCC, while the fusion rate was significantly reduced by DAPT, a kind of EMT blocker. Therefore, epithelial cells can increase spontaneously cell fusion with OSCC by EMT. Our study may provide a new insight to link among tumor microenvironment, cell fusion, and cancer.

B7-H1 and B7-DC receptors of oral squamous carcinoma cells are upregulated by Porphyromonas gingivalis

Immunobiology ◽  
2011 ◽  
Vol 216 (12) ◽  
pp. 1302-1310 ◽  
Author(s):  
Sabine Groeger ◽  
Eugen Domann ◽  
Jose R. Gonzales ◽  
Trinad Chakraborty ◽  
Joerg Meyle
Keyword(s):  
Porphyromonas Gingivalis ◽  
Squamous Carcinoma ◽  
Carcinoma Cells ◽  
Squamous Carcinoma Cells ◽  
Oral Squamous Carcinoma

scholarly journals The Migration and Invasion of Oral Squamous Carcinoma Cells: Matrix, Growth Factor and Signalling Involvement

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2633
Author(s):  
Ian R. Ellis
Keyword(s):  
Growth Factor ◽  
Cancer Cells ◽  
Squamous Carcinoma ◽  
Carcinoma Cells ◽  
Migration And Invasion ◽  
Squamous Carcinoma Cells ◽  
Oral Squamous Carcinoma

The link between the migration of cancer cells and the spread of cancers has been established for many years [...]

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