P07.10: Fetal heart navigator (FHN): a novel method to get key diagnostic fetal echocardiographic views and initial application in diagnosis of fetal conotruncal heart defects

2014 ◽  
Vol 44 (S1) ◽  
pp. 222-222
Author(s):  
B.W. Zhao ◽  
Y.H. Huang ◽  
Y.Z. Xu ◽  
X.L. Song ◽  
M. Pan ◽  
...  
Keyword(s):  
Fetal Heart ◽  
Heart Defects ◽  
Conotruncal Heart Defects ◽  
Initial Application ◽  
Novel Method

scholarly journals FETAL CARDIAC STRUCTURE DETECTION FROM ULTRASOUND SEQUENCES

2012 ◽  
pp. 53-57
Author(s):  
RESHMI MARIAM REJI JACOB ◽  
S. PRABAKAR ◽  
DR.K. PORKUMARAN
Keyword(s):  
Clustering Algorithm ◽  
Fetal Heart ◽  
Heart Defects ◽  
Region Of Interest ◽  
Appearance Model ◽  
Cardiac Structure ◽  
Structure Detection ◽  
Heart Abnormalities ◽  
Novel Method ◽  
Effective Diagnosis

Fetal heart abnormalities are the most common congenital anomalies and are also the leading cause of infant mortality related to birth defects. More than one-third of all malformations found after delivery are congenital heart defects. The prenatal detection of fetal cardiac structure is difficult because of its small size and rapid movements but is important for the early and effective diagnosis of congenital cardiac defects. A novel method is proposed for the detection of fetal cardiac structure from ultrasound sequences. An initial pre-processing is done to remove noise and enhance the images. An effective K means clustering algorithm is applied to the images to segment the region of interest. Finally an active appearance model is proposed to detect the structure of fetal heart.

scholarly journals One-carbon metabolite levels in mid-pregnancy and risks of conotruncal heart defects

2014 ◽  
Vol 100 (2) ◽  
pp. 107-115 ◽  
Author(s):  
Gary M. Shaw ◽  
Wei Yang ◽  
Suzan L. Carmichael ◽  
Stein Emil Vollset ◽  
Charlotte A. Hobbs ◽  
...  
Keyword(s):  
Heart Defects ◽  
Conotruncal Heart Defects

Conotruncal heart defects and chromosome 22q11microdeletion

1997 ◽  
Vol 130 (4) ◽  
pp. 675-676 ◽  
Author(s):  
M.Cristina Digilio ◽  
Bruno Marino ◽  
Aldo Giannotti ◽  
Giuseppe Novelli ◽  
Bruno Dallapiccola
Keyword(s):  
Heart Defects ◽  
Conotruncal Heart Defects

Collaborative Study on 4-Dimensional Echocardiography for the Diagnosis of Fetal Heart Defects

2010 ◽  
Vol 29 (11) ◽  
pp. 1573-1580 ◽  
Author(s):  
Jimmy Espinoza ◽  
Wesley Lee ◽  
Christine Comstock ◽  
Roberto Romero ◽  
Lami Yeo ◽  
...  
Keyword(s):  
Fetal Heart ◽  
Heart Defects ◽  
Collaborative Study ◽  
Dimensional Echocardiography

scholarly journals Gene-Gene Interactions in the Folate Metabolic Pathway and the Risk of Conotruncal Heart Defects

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Philip J. Lupo ◽  
Elizabeth Goldmuntz ◽  
Laura E. Mitchell
Keyword(s):  
Risk Factors ◽  
Metabolic Pathway ◽  
Heart Defects ◽  
Independent Study ◽  
Gene Interactions ◽  
Genotype Combination ◽  
Conotruncal Heart Defects ◽  
Metabolic Genes ◽  
Functional Variants ◽  
Maternal Gene

Conotruncal and related heart defects (CTRD) are common, complex malformations. Although there are few established risk factors, there is evidence that genetic variation in the folate metabolic pathway influences CTRD risk. This study was undertaken to assess the association between inherited (i.e., case) and maternal gene-gene interactions in this pathway and the risk of CTRD. Case-parent triads (n=727), ascertained from the Children's Hospital of Philadelphia, were genotyped for ten functional variants of nine folate metabolic genes. Analyses of inherited genotypes were consistent with the previously reported association betweenMTHFRA1298C and CTRD (adjustedP=.02), but provided no evidence that CTRD was associated with inherited gene-gene interactions. Analyses of the maternal genotypes provided evidence of aMTHFRC677T/CBS844ins68 interaction and CTRD risk (unadjustedP=.02). This association is consistent with the effects of this genotype combination on folate-homocysteine biochemistry but remains to be confirmed in independent study populations.

Ultrasound examination of pregnant women in diagnosing fetal cardiac pathology

2020 ◽  
Vol 69 (2) ◽  
pp. 43-50
Author(s):  
Viktoria A. Lim
Keyword(s):  
Pregnant Women ◽  
Fetal Heart ◽  
Fetal Echocardiography ◽  
Heart Defects ◽  
Care Service ◽  
Ultrasound Screening ◽  
Atrioventricular Canal ◽  
Cardiac Pathology ◽  
Organ Systems ◽  
Atrioventricular Canal Defect

Hypothesis/aims of study. Fetal heart defects are the most common malformations causing infant mortality. The task of the obstetric care service is to make a timely diagnosis, which includes high-quality ultrasound screening and, if necessary, fetal echocardiography. This study aimed to compare fetal echocardiography with postpartum echocardiography. Study design, materials and methods. 101 pregnant women with both isolated fetal heart defects and combined pathology were examined for the period 20172019. Results. The greatest number of heart defects was detected at 2331 weeks of gestation. The structure of the malformations is diverse, the most common one being a complete form of the atrioventricular canal defect. In multiple pregnancies, complex heart defects were often combined with abnormalities in other organ systems. Conclusion. It is recommended to describe the heart structure in detail from 2122 weeks of pregnancy. If cardiac pathology is detected in utero, it is mandatory to conduct an examination of other fetal organs.

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