Residue 285 in Cytochrome P450 2B4 Lacking the NH2-Terminal Hydrophobic Sequence Has a Role in the Functional Association of NADPH–Cytochrome P450 Reductase

Functional Association ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

The cytochrome P450 2B4-NADPH cytochrome P450 reductase electron transfer complex is not formed by charge-pairing.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42093-5 ◽

1992 ◽

Vol 267 (21) ◽

pp. 14669-14676

Author(s):

A.I. Voznesensky ◽

J.B. Schenkman

Keyword(s):

Electron Transfer ◽

Cytochrome P450 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Nadph Cytochrome P450 Reductase ◽

Electron Transfer Complex

Mass spectrometry identification of cytochrome P450 2B4 interaction sites for NADPH: Cytochrome P450 reductase

Biochemistry (Moscow) Supplement Series B Biomedical Chemistry ◽

10.1134/s1990750809040052 ◽

2009 ◽

Vol 3 (4) ◽

pp. 361-371

Author(s):

A. V. Ivanov ◽

A. T. Kopylov ◽

V. G. Zgoda ◽

I. Yu. Toropygin ◽

E. V. Khryapova ◽

...

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Interaction Sites ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Mass Spectrometry Identification ◽

Cytochrome b5 and NADPH‐Cytochrome P450 Reductase Compete for a Binding Site on the Proximal Surface of Cytochrome P450 2B4

The FASEB Journal ◽

10.1096/fasebj.21.5.a670-d ◽

2007 ◽

Vol 21 (5) ◽

Author(s):

Lucy Waskell ◽

Haoming Zhang ◽

Sang‐Choul Im ◽

Reza Razeghifard

Keyword(s):

Cytochrome P450 ◽

Binding Site ◽

Cytochrome B5 ◽

Proximal Surface ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Semi artificial Hydroxylating Enzymes Created by Flavins Binding to Cytochrome P450 2B4 and by Bleomycin Binding to NADPH - Cytochrome P450 Reductase

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1994.1510 ◽

1994 ◽

Vol 200 (2) ◽

pp. 722-725 ◽

Cited By ~ 10

Author(s):

V.Y. Uvarov ◽

V.V. Shumyantseva ◽

E.A. Bykhovskaya ◽

L.N. Kolyada ◽

A.L. Archakov

Keyword(s):

Cytochrome P450 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Cytochromeb5Inhibits Electron Transfer from NADPH-Cytochrome P450 Reductase to Ferric Cytochrome P450 2B4

Journal of Biological Chemistry ◽

10.1074/jbc.m709094200 ◽

2007 ◽

Vol 283 (9) ◽

pp. 5217-5225 ◽

Cited By ~ 45

Author(s):

Haoming Zhang ◽

Djemel Hamdane ◽

Sang-Choul Im ◽

Lucy Waskell

Keyword(s):

Electron Transfer ◽

Cytochrome P450 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

AFM Study of Membrane Proteins, Cytochrome P450 2B4, and NADPH–Cytochrome P450 Reductase and Their Complex Formation

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1999.1412 ◽

1999 ◽

Vol 371 (1) ◽

pp. 1-7 ◽

Cited By ~ 35

Author(s):

Olga I. Kiselyova ◽

Igor V. Yaminsky ◽

Yuri D. Ivanov ◽

Irina P. Kanaeva ◽

Vadim Yu. Kuznetsov ◽

...

Keyword(s):

Cytochrome P450 ◽

Membrane Proteins ◽

Complex Formation ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Identification of Key Residues in Rabbit Liver Microsomal Cytochrome P450 2B4: Importance in Interactions with NADPH-Cytochrome P450 Reductase

The Journal of Biochemistry ◽

10.1093/oxfordjournals.jbchem.a022578 ◽

2000 ◽

Vol 127 (1) ◽

pp. 163-169 ◽

Cited By ~ 21

Author(s):

M. Lehnerer ◽

J. Schulze ◽

K. Achterhold ◽

D. F.V. Lewis ◽

P. Hlavica

Keyword(s):

Cytochrome P450 ◽

Rabbit Liver ◽

Microsomal Cytochrome ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Microsomal Cytochrome P450 ◽

Nadph Cytochrome P450 Reductase ◽

Key Residues

Interactions of cytochrome P450 2B4 with NADPH-cytochrome P450 reductase studied by fluorescent probe

Biochimie ◽

10.1016/s0300-9084(97)82531-x ◽

1996 ◽

Vol 78 (8-9) ◽

pp. 734-743 ◽

Cited By ~ 26

Author(s):

D.R. Davydov ◽

T.V. Knyushko ◽

I.P. Kanaeva ◽

Y.M. Koen ◽

N.F. Samenkova ◽

...

Keyword(s):

Cytochrome P450 ◽

Fluorescent Probe ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)67801-4 ◽

1991 ◽

Vol 266 (6) ◽

pp. 3372-3375

Author(s):

T Shimizu ◽

T Tateishi ◽

M Hatano ◽

Y Fujii-Kuriyama

Keyword(s):

Cytochrome P450 ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Catalytic Function ◽

Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase. Implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells

Anti-Cancer Drugs ◽

10.1097/cad.0b013e32834fcf4f ◽

2012 ◽

Vol 23 (4) ◽

pp. 393-405 ◽

Cited By ~ 5

Author(s):

Dorota Kostrzewa-Nowak ◽

Bohdan Bieg ◽

Mark J.I. Paine ◽

C. Roland Wolf ◽

Jolanta Tarasiuk

Keyword(s):

Cytochrome P450 ◽

Multidrug Resistant ◽

Structural Factors ◽

Hl60 Cells ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anthraquinone Derivatives ◽