Degeneration of Cone Photoreceptors Induced by Expression of the Mas1 Protooncogene

2000 ◽  
Vol 163 (1) ◽  
pp. 207-219 ◽  
Author(s):  
Xiaoping Xu ◽  
Alexander B. Quiambao ◽  
Luisa Roveri ◽  
Machelle T. Pardue ◽  
Jeffrey L. Marx ◽  
...  
Keyword(s):  
Cone Photoreceptors

scholarly journals Distinct and Atypical Intrinsic and Extrinsic Cell Death Pathways between Photoreceptor Cell Types upon Specific Ablation of Ranbp2 in Cone Photoreceptors

PLoS Genetics ◽  
2013 ◽  
Vol 9 (6) ◽  
pp. e1003555 ◽  
Author(s):  
Kyoung-in Cho ◽  
MdEmdadul Haque ◽  
Jessica Wang ◽  
Minzhong Yu ◽  
Ying Hao ◽  
...  
Keyword(s):  
Cell Death ◽  
Photoreceptor Cell ◽  
Cell Types ◽  
Cone Photoreceptors ◽  
Cell Death Pathways

Two opposite effects of ATP on the apparent sensitivity of the cGMP-gated channel of the carp retinal cone

1997 ◽  
Vol 14 (4) ◽  
pp. 609-615 ◽  
Author(s):  
Shu-Ichi Watanabe ◽  
Jing Shen
Keyword(s):  
Cone Photoreceptors ◽  
Apparent Affinity ◽  
Enhancing Effect ◽  
Cyclic Monophosphate ◽  
Maximum Current ◽  
Gated Channel ◽  
Retinal Cone ◽  
A Current

AbstractEffects of ATP on the activity of cGMP-gated channels from carp cone photoreceptors were studied. In 29% of the patches examined (N = 45), ATP (1 mM) enhanced a current evoked by cGMP (20 μM, up to about 100%), in 33%, ATP suppressed it by up to about 90%, and in the remaining 38%, ATP had no effect. ATP showed similar effects on a current evoked by 8-bromoguanosine 3′,5′-cyclic monophosphate (2 μM, enhancing in 42% of the patches, suppressing in 25%, no effect in 33%, N = 12), suggesting that the effects were not through modulation of the phosphodiesterase. Both of the effects, enhancement and suppression, were produced by a change in apparent affinity for cGMP, since (1) the maximum current evoked by cGMP of the saturating concentration (≥1 mM) was not affected, and (2) the A1/2 value decreased by approximately 45% (N = 2) or increased by approximately 25% (N = 2). A lower pH (approximately 6) facilitated the enhancing effect. ATP-γ-S (1 mM) showed a suppressing effect in 80% of the patches and no effect in 20% of the patches (N = 10). However, ATP-γ-S did not show an enhancing effect. Thus, ATP had two opposite effects through different mechanisms on the apparent sensitivity of the channel to cGMP; increasing and decreasing.

scholarly journals Mutually exclusive expression of human red and green visual pigment-reporter transgenes occurs at high frequency in murine cone photoreceptors

1999 ◽  
Vol 96 (9) ◽  
pp. 5251-5256 ◽  
Author(s):  
Y. Wang ◽  
P. M. Smallwood ◽  
M. Cowan ◽  
D. Blesh ◽  
A. Lawler ◽  
...  
Keyword(s):  
High Frequency ◽  
Visual Pigment ◽  
Cone Photoreceptors

Digoxin-Induced Reversible Dysfunction of the Cone Photoreceptors in Monkeys

2014 ◽  
Vol 55 (2) ◽  
pp. 881 ◽  
Author(s):  
Junzo Kinoshita ◽  
Noriaki Iwata ◽  
Tomofumi Kimotsuki ◽  
Mitsuya Yasuda
Keyword(s):  
Cone Photoreceptors

scholarly journals Images of cone photoreceptors in the living human eye

1996 ◽  
Vol 36 (8) ◽  
pp. 1067-1079 ◽  
Author(s):  
Donald T. Miller ◽  
David R. Williams ◽  
G. Michael Morris ◽  
Junzhong Liang
Keyword(s):  
Cone Photoreceptors ◽  
Human Eye

scholarly journals Colour cues proved to be more informative for dogs than brightness

2013 ◽  
Vol 280 (1766) ◽  
pp. 20131356 ◽  
Author(s):  
Anna A. Kasparson ◽  
Jason Badridze ◽  
Vadim V. Maximov
Keyword(s):  
Colour Vision ◽  
Visual Stimuli ◽  
Cone Photoreceptors ◽  
Lighting Conditions ◽  
Chromatic Cues

The results of early studies on colour vision in dogs led to the conclusion that chromatic cues are unimportant for dogs during their normal activities. Nevertheless, the canine retina possesses two cone types which provide at least the potential for colour vision. Recently, experiments controlling for the brightness information in visual stimuli demonstrated that dogs have the ability to perform chromatic discrimination. Here, we show that for eight previously untrained dogs colour proved to be more informative than brightness when choosing between visual stimuli differing both in brightness and chromaticity. Although brightness could have been used by the dogs in our experiments (unlike previous studies), it was not. Our results demonstrate that under natural photopic lighting conditions colour information may be predominant even for animals that possess only two spectral types of cone photoreceptors.

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