An Alternative Chinese Keyboard Layout Design for Single-Digit Typists

2006 ◽  
pp. 919-925
Author(s):  
Ming-Chung Chen ◽  
Ting-Fang Wu
Keyword(s):  
Layout Design ◽  
Single Digit ◽  
Keyboard Layout

scholarly journals An Iterative Methodolgy to Improve TV Onscreen Keyboard Layout Design through Evaluation of User Studies

2012 ◽  
Vol 2 (5) ◽  
pp. 81-91 ◽  
Author(s):  
Debatri Chatterjee ◽  
Aniruddha Sinha ◽  
Arpan Pal ◽  
Anupam Basu
Keyword(s):  
Layout Design ◽  
User Studies ◽  
Keyboard Layout

Application of Fractal Growth Patterns in Housing Layout Design

2016 ◽  
Vol 3 (2) ◽  
pp. 185-208
Author(s):  
SUBHADHA BATTINA
Keyword(s):  
Layout Design ◽  
Growth Patterns ◽  
Fractal Growth ◽  
Housing Layout

Half- Sandwich cyclopentadienylruthenium(II) Complexes: A New Antimalarial Chemotype

2020 ◽  
Author(s):  
Sofia Alexandra Milheiro ◽  
Joana Gonçalves ◽  
Ricardo Lopes ◽  
Margarida Madureira ◽  
Lis Lobo ◽  
...  
Keyword(s):  
Mammalian Cells ◽  
Blood Stage ◽  
Nuclear Accumulation ◽  
Selective Absorption ◽  
Asexual Parasite ◽  
Single Digit ◽  
Liver Stage ◽  
Dual Stage ◽  
Fluorescent Compounds ◽  
Half Sandwich

<p><a>A small library of “half-sandwich” cyclopentadienylruthenium(II) compounds of general formula [(</a>η<sup>5</sup>-C<sub>5</sub>R<sub>5</sub>)Ru(PPh<sub>3</sub>)(N-N)][PF<sub>6</sub>], a scaffold hitherto unfeatured in the toolbox of antiplasmodials, was screened for activity against the blood stage of CQ-sensitive 3D7-GFP, CQ-resistant Dd2 and artemisinin-resistant IPC5202 <i>Plasmodium falciparum</i> strains, and the liver stage of <i>P. berghei</i>. The best performing compounds displayed dual-stage activity, with single-digit nM IC<sub>50</sub> values against blood stage malaria parasites, nM activity against liver stage parasites, and residual cytotoxicity against mammalian cells (HepG2, Huh7). Parasitic absorption/distribution of 7-nitrobenzoxadiazole-appended fluorescent compounds <b>Ru4</b> and <b>Ru5</b> was investigated by confocal fluorescence microscopy, revealing parasite-selective absorption in infected erythrocytes and nuclear accumulation of both compounds. The lead compound <b>Ru2</b> impaired asexual parasite differentiation, exhibiting fast parasiticidal activity against both ring and trophozoite stages of a synchronized <i>P. falciparum</i> 3D7 strain. These results point to cyclopentadienylruthenium(II) complexes as a highly promising chemotype for the development of dual-stage antiplasmodials.</p>

The Effects of Keyboard Layout and Size on Smartphone Typing Performance

2020 ◽  
Vol 64 (1) ◽  
pp. 985-989
Author(s):  
Colton J. Turner ◽  
Barbara S. Chaparro ◽  
Inga M. Sogaard ◽  
Jibo He
Keyword(s):  
Error Rates ◽  
Hand Posture ◽  
Standard Keyboard ◽  
Keyboard Layout

Usability and typing performance on a smartphone with two unique QWERTY keyboard layouts (standard vs. curved) on two phone sizes (4.0-inch vs. 5.5-inch displays) was investigated in this study. The effect of hand posture was also investigated (one- vs. two-thumbs). Results show users typed the slowest when using one thumb with the curved keyboard on the small phone (15 WPM), and the fastest when using two thumbs with the standard keyboard on the large phone (24 WPM). Typing performance with the curved keyboard on the large phone size (19 WPM) did not differ between typing with one thumb using the standard keyboard on the large or small phone, or with two thumbs using the standard keyboard on the small phone. Error rates were higher when using the curved keyboard, regardless of phone size. Subjectively, the curved keyboard was rated inferior for both phone sizes in comparison to the standard layout.

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