Leo-III is an automated theorem prover for (polymorphic) higher-order logic which supports all common TPTP dialects, including THF, TFF and FOF as well as their rank-1 polymorphic derivatives. It is based on a paramodulation calculus with ordering constraints and, in tradition of its predecessor LEO-II, heavily relies on cooperation with external first-order theorem provers.Unlike LEO-II, asynchronous cooperation with typed first-order provers and an agent-based internal cooperation scheme is supported. In this paper, we sketch Leo-III's underlying calculus, survey implementation details and give examples of use.