scholarly journals Chronic Oral l-Carnitine Supplementation Drives Marked Plasma TMAO Elevations in Patients with Organic Acidemias Despite Dietary Meat Restrictions

2016 ◽  
pp. 39-44 ◽  
Author(s):  
Marcus J. Miller ◽  
Bret L. Bostwick ◽  
Adam D. Kennedy ◽  
Taraka R. Donti ◽  
Qin Sun ◽  
...  
Keyword(s):  
Carnitine Supplementation ◽  
Organic Acidemias

Severe secondary mitochondrial dysfunction in classical organic acidemias

2006 ◽  
Vol 37 (06) ◽  
Author(s):  
MA Morath
Keyword(s):  
Mitochondrial Dysfunction ◽  
Organic Acidemias

Effect of L-carnitine supplementation on seminal plasma quality of Iraqi drakes

2011 ◽  
Vol 3 (12) ◽  
pp. 10-14
Author(s):  
Hazim J Al-Daraji ◽  
◽  
Anmar O Tahir
Keyword(s):  
Seminal Plasma ◽  
Carnitine Supplementation

The Effects of L-Carnitine Supplementation on Serum Lipids: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2019 ◽  
Vol 25 (30) ◽  
pp. 3266-3281 ◽  
Author(s):  
Hadis Fathizadeh ◽  
Alireza Milajerdi ◽  
Željko Reiner ◽  
Fariba Kolahdooz ◽  
Maryam Chamani ◽  
...  
Keyword(s):  
Serum Lipids ◽  
Ldl Cholesterol ◽  
Meta Analysis ◽  
Hdl Cholesterol ◽  
Health Conditions ◽  
Carnitine Supplementation ◽  
Randomized Controlled ◽  
Cholesterol Levels ◽  
Vldl Cholesterol ◽  
Subgroup Analyses

Background: The findings of trials investigating the effects of L-carnitine administration on serum lipids are inconsistent. This meta-analysis of randomized controlled trials (RCTs) was performed to summarize the effects of L-carnitine intake on serum lipids in patients and healthy individuals. Methods: Two authors independently searched electronic databases including MEDLINE, EMBASE, Cochrane Library, Web of Science, PubMed and Google Scholar from 1990 until August 1, 2019, in order to find relevant RCTs. The quality of selected RCTs was evaluated using the Cochrane Collaboration risk of bias tool. Cochrane’s Q test and I-square (I2) statistic were used to determine the heterogeneity across included trials. Weight mean difference (SMD) and 95% CI between the two intervention groups were used to determine pooled effect sizes. Subgroup analyses were performed to evaluate the source of heterogeneity based on suspected variables such as, participant’s health conditions, age, dosage of L-carnitine, duration of study, sample size, and study location between primary RCTs. Results: Out of 3460 potential papers selected based on keywords search, 67 studies met the inclusion criteria and were eligible for the meta-analysis. The pooled results indicated that L-carnitine administration led to a significant decrease in triglycerides (WMD: -10.35; 95% CI: -16.43, -4.27), total cholesterol (WMD: -9.47; 95% CI: - 13.23, -5.70) and LDL-cholesterol (LDL-C) concentrations (WMD: -6.25; 95% CI: -9.30, -3.21), and a significant increase in HDL-cholesterol (HDL-C) levels (WMD: 1.39; 95% CI: 0.21, 2.57). L-carnitine supplementation did not influence VLDL-cholesterol concentrations. When we stratified studies for the predefined factors such as dosage, and age, no significant effects of the intervention on triglycerides, LDL-C, and HDL-C levels were found. Conclusion: This meta-analysis demonstrated that L-carnitine administration significantly reduced triglycerides, total cholesterol and LDL-cholesterol levels, and significantly increased HDL-cholesterol levels in the pooled analyses, but did not affect VLDL-cholesterol levels; however, these findings were not confirmed in our subgroup analyses by participant’s health conditions, age, dosage of L-carnitine, duration of study, sample size, and study location.

Effects of L-carnitine supplementation on heart rate and selected metabolic responses in esting and exercising horses: A placebo-controlled double blind study

2005 ◽  
Vol 21 (7) ◽  
pp. 107-109 ◽  
Author(s):  
A Niemeyer ◽  
I Vervuert ◽  
K Appelt ◽  
H Kluge ◽  
S Jacobs ◽  
...  
Keyword(s):  
Heart Rate ◽  
Blind Study ◽  
Metabolic Responses ◽  
Double Blind Study ◽  
Carnitine Supplementation ◽  
Double Blind

Anemia and carnitine supplementation in hemodialyzed patients

1999 ◽  
Vol 55 (Suppl. 69) ◽  
pp. 93-106 ◽  
Author(s):  
JOSEF KLETZMAYR ◽  
GERT MAYER ◽  
ELISABETH LEGENSTEIN ◽  
GERTRAUD HEINZ-PEER ◽  
THOMAS LEITHA ◽  
...  
Keyword(s):  
Carnitine Supplementation

scholarly journals Effects of oral L-carnitine and DL-carnitine supplementation on alloxan-diabetic rats

2012 ◽  
Vol 55 (1) ◽  
pp. 81-88 ◽  
Author(s):  
Roberto Barbosa Bazotte ◽  
Gisele Lopes-Bertolini
Keyword(s):  
Diabetic Rats ◽  
Carnitine Supplementation
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