Without effective architectural oversight, enterprises risk stifling their ability to innovate, because vendor products are too tightly woven into their key business processes, which impedes the evolution of their technology environment in support of business needs. Vendors gain negotiation leverage due to monopoly on the technology that supports key enterprise processes and capabilities. The goal of this chapter is to provide practical guidance on business flexibility advantages through carefully managed vendor diversification options for enterprises that are implementing Service-driven applications and integration solutions. The approach presented in this chapter recommends adherence to four basic principles, namely, owning the ability to control delivery channels and integration, compartmentalizing concepts into fulfillment roles in the Service-driven enterprise, using a vendor agnostic enterprise service interface, and owning the key data. The dual reinforcing concepts of ownership and control underpin the vendor diversification opportunities. A reference architecture is presented that distills these principles into a conceptual model that can be applied to any enterprise. A real world transportation and logistics business enterprise integration project is used as an example to illustrate the advantages of using vendor agnostic principles in a Service-driven environment.