Renin-Angiotensin System Proteases and the Cardiometabolic Syndrome: Pathophysiological, Clinical and Therapeutic Implications

Author(s):  
Guido Lastra ◽  
Camila Manrique ◽  
James R. Sowers
2020 ◽  
Vol 217 (8) ◽  
Author(s):  
Betty Diamond

The renin–angiotensin system (RAS) has long been appreciated as a major regulator of blood pressure, but has more recently been recognized as a mechanism for modulating inflammation as well. While there has been concern in COVID-19 patients over the use of drugs that target this system, the RAS has not been explored fully as a druggable target. The abbreviated description of the RAS suggests that its dysregulation may be at the center of COVID-19.


Hypertension ◽  
2010 ◽  
Vol 55 (2) ◽  
pp. 207-213 ◽  
Author(s):  
Anderson J. Ferreira ◽  
Robson A.S. Santos ◽  
Chastity N. Bradford ◽  
Adam P. Mecca ◽  
Colin Sumners ◽  
...  

1994 ◽  
Vol 32 (2) ◽  
pp. 117-125 ◽  
Author(s):  
David L. Crandall ◽  
Helen E. Herzlinger ◽  
Brian D. Saunders ◽  
John G. Kral

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