Microscopic Examination of the Urinary Sediment to Differentiate High from Low Renal Bleeding

Author(s):  
G. Berry Schumann ◽  
Janet L. Schumann
Kidney360 ◽  
2020 ◽  
pp. 10.34067/KID.0004022020
Author(s):  
Vipin Varghese ◽  
Maria Soledad Rivera ◽  
Ali A. Alalwan ◽  
Ayman M. Alghamdi ◽  
Manuel E. Gonzalez ◽  
...  

Background. Microscopic examination of the urinary sediment (MicrExUrSed) is an established diagnostic tool for acute kidney injury (AKI). Single inspection of urine during the course of AKI is a mere snapshot affected by timing. We hypothesized that longitudinal MicrExUrSed provides information not identified in a single inspection. Methods. MicrExUrSed was undertaken in patients with AKI stage >= 2 and suspected intrinsic cause of AKI seen for nephrology consultation over a 2-year period. MicrExUrSed was performed on the day of consultation and repeated at a second (2 - 3 days later) and/or third (4 - 10 days later) interval. Cast scores were assigned to each specimen. Chawla scores (CS) 3 to 4 and Perazella scores (PS) 2 to 4 were categorized as consistent with acute tubular injury (ATI), whereas CS 1 to 2 and PS 0 to 1 were categorized as non-diagnostic for ATI (non-ATI). Non-recovering AKI was defined as a rise in serum creatinine (sCr) ≥ 0.1 mg/dL between microscopy intervals. Results. At least 2 consecutive MicrExUrSed were performed in 121 patients [46% women, mean age 61 ± 14, mean sCr at consult of 3.3 +/- 1.9 mg/dL]. On day 1, a CS and PS consistent with non-ATI was assigned to 64 (53%) and 70 (58%) patients, respectively. After a subsequent MicrExUrSed, CS and PS changed to ATI in 14 (22%) and 16 (23%) patients. Thus, 20 - 24% of patients only revealed evidence of ATI after serial MicrExUrSed was performed. Patients with non-recovering AKI were more likely to change their PS to ATI category [odds ratio: 5.8 (CI:1.7-19.3; p=0.005) and positive likelihood ratio: 2.0 (CI: 1.3-2.9)]. Conclusion. Serial MicrExUrSed revealed diagnostic findings of ATI not identified in a single examination. A repeat MicrExUrSed may be warranted in cases of AKI of unclear etiology or not recovering.


JAMA ◽  
1978 ◽  
Vol 240 (19) ◽  
pp. 2044b-2044 ◽  
Author(s):  
R. M. Donauer

JAMA ◽  
1978 ◽  
Vol 240 (19) ◽  
pp. 2044
Author(s):  
Robert M. Donauer

1994 ◽  
Vol 15 (3) ◽  
pp. 102-108
Author(s):  
Douglas S. Fitzwater ◽  
Robert J. Wyatt

Hematunia occurs in approximately 1.5% of children. It is important in evaluating the patient who has hematuna to make sure that a positive dipstick test is accompanied by RBCs on the microscopic examination. Hematunia is defined by several parameters, the most common of which are 6 cells/cc of urine in a counting chamber or 2 cells per high-power field in a urinary sediment. Although the differential diagnosis for hematuria is extensive, the most important differentiating feature is the presence or absence of proteinuria. Those who have significant proteinunia deserve a rapid evaluation and early referral to a nephrologist. Those who do not have proteinunia should be followed and a step-wise evaluation performed. Finally, most patients who have asymptomatic microscopic hematunia do not have clinically significant glomenular pathology.


2000 ◽  
Vol 297 (1-2) ◽  
pp. 225-237 ◽  
Author(s):  
Jozsef Lakatos ◽  
Tibor Bodor ◽  
Zoltan Zidarics ◽  
Judit Nagy

2013 ◽  
Vol 462-463 ◽  
pp. 9-12
Author(s):  
Kai Xiang Li ◽  
Ji Hong Feng ◽  
Hao He ◽  
Hua Juan Bai

The purpose of this paper is to put up a device for urinary sediment detection with a homemade microscope and a CCD, and to test the feasibility of the device. In this study, we use a capillary to absorb the urinalysis control (UC) which is diluted 500 times, and drip it into a counting pool of a urinary sediment quantitative analysis board (USQAB). In this setup device, we detect 30 counting pools in this analysis board with microscopic examination in total. Further, we count the number of red blood cells (RBC) and white blood cells (WBC) of every counting pool, and calculate the average number of RBC and WBC of 30 counting pools. Though this detection device, we are able to get 30 groups of imaging results clearly while the number of RBC and WBC in each counting pool fluctuates around the mean value. The result indicates that the setup detection device in this experiment is simple and feasible.


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