Oropharyngeal Carcinoma

2000 ◽  
pp. 107-113
Author(s):  
Derek C. Allen
Keyword(s):  
Oropharyngeal Carcinoma

Assessment of Decannulation Timing in Postoperative Oral or Oropharyngeal Carcinoma Patients

2017 ◽  
Vol 68 (2) ◽  
pp. 166-166
Author(s):  
H. Tsuzuki ◽  
Y. Fujimoto ◽  
M. Hiramatsu ◽  
N. Nishio ◽  
N. Mukouyama ◽  
...  
Keyword(s):  
Oropharyngeal Carcinoma

scholarly journals Evaluation of HPV16 E7 expression in head and neck carcinoma cell lines and clinical specimens

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Koji Kitamura ◽  
Keisuke Nimura ◽  
Rie Ito ◽  
Kotaro Saga ◽  
Hidenori Inohara ◽  
...  
Keyword(s):  
Head And Neck ◽  
Cell Lines ◽  
Carcinoma Cell ◽  
Head And Neck Carcinoma ◽  
Oropharyngeal Carcinoma ◽  
Human Embryonic Kidney Cells ◽  
Clinical Specimens ◽  
Hpv Dna ◽  
Hpv E6 ◽  
Carcinoma Cell Lines

AbstractHuman papillomavirus (HPV) 16 infection in the oropharynx is one of the major risk factors for oropharyngeal carcinoma. Although the HPV E6 and E7 proteins are known to have a role in head and neck carcinogenesis, whether their expression is maintained once the tumour has developed still remains unclear. We evaluated the expression of these proteins in HPV16-positive cancer cell lines and clinical oropharyngeal specimens. Two out of the four commercially available antibodies directed against the E7 protein could detect the E7 protein overexpressed in the 293FT cells, human embryonic kidney cells, although none of the four commercially available anti-E6 antibodies could detect the overexpressed E6 protein. Whereas HPV16-positive head and neck or cervical carcinoma cell lines expressed the E7 mRNA, the antibodies with an ability to detect the E7 protein could not detect it in western blotting in these HPV16-positive cell lines. In clinical specimens, E7 protein was partially detected in p16-positive area in p16-positive and HPV16 DNA-positive samples, but not in p16-negative and HPV DNA-negative or p16-positive and HPV DNA-negative samples. Consistent with these findings, the E7 protein was poorly translated from the endogenous structure of the E7 mRNA, although significant E7 mRNA expression was detected in these samples. Our findings indicate that E7 protein is partially expressed in p16-positive area in p16-positive and HPV16 DNA-positive clinical specimens.

Survival outcomes with concomitant chemoradiotherapy in older adults with oropharyngeal carcinoma in an era of increasing human papillomavirus (HPV) prevalence

Oral Oncology ◽  
2019 ◽  
Vol 99 ◽  
pp. 104472 ◽  
Author(s):  
Diana J. Lu ◽  
Michael Luu ◽  
Anthony T. Nguyen ◽  
Kevin S. Scher ◽  
Jon Mallen-St. Clair ◽  
...  
Keyword(s):  
Older Adults ◽  
Human Papillomavirus ◽  
Survival Outcomes ◽  
Oropharyngeal Carcinoma ◽  
Concomitant Chemoradiotherapy ◽  
Hpv Prevalence

scholarly journals Prognostic Value of FDG-PET in Patients with Oropharyngeal Carcinoma Treated with Concurrent Chemoradiotherapy

2008 ◽  
Vol 10 (4) ◽  
Author(s):  
Keisuke Enomoto ◽  
Hidenori Inohara ◽  
Ichiro Higuchi ◽  
Kenichiro Hamada ◽  
Yoichiro Tomiyama ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Prognostic Value ◽  
Concurrent Chemoradiotherapy ◽  
Oropharyngeal Carcinoma

Prognostic value of the lymph node ratio in oropharyngeal carcinoma stratified for HPV-status

2017 ◽  
Vol 275 (2) ◽  
pp. 515-524 ◽  
Author(s):  
Christian Jacobi ◽  
Josepha Rauch ◽  
Jan Hagemann ◽  
Thomas Lautz ◽  
Maximilian Reiter ◽  
...  
Keyword(s):  
Lymph Node ◽  
Prognostic Value ◽  
Lymph Node Ratio ◽  
Oropharyngeal Carcinoma ◽  
Hpv Status ◽  
Node Ratio
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