Clinical and Translational Research Informatics Education and Training

2013 ◽  
pp. 167-178
Author(s):  
Peter J. Embi ◽  
Philip R. O. Payne
Keyword(s):  
Translational Research ◽  
Education And Training ◽  
And Training ◽  
Clinical And Translational Research

scholarly journals Synovial biopsies in clinical practice and research: current developments and perspectives

2020 ◽  
Author(s):  
Hanna Johnsson ◽  
Aurélie Najm
Keyword(s):  
Translational Research ◽  
Clinical Applications ◽  
Synovial Biopsy ◽  
Ultrasound Guided ◽  
Histological Studies ◽  
Training Requirements ◽  
The Past ◽  
Cell Subpopulations ◽  
And Training ◽  
Clinical And Translational Research

AbstractSynovial biopsy techniques have developed and widely expanded over the past few years, in particular due to the development of ultrasound-guided procedures. This article reviews the different techniques, clinical applications, and the latest advances in translational research as well as current challenges and perspectives. The first part focuses on different techniques available for biopsy, along with their feasibility, success rate, tolerance, and training requirements. In the second part, clinical applications are described. Data on diagnostic performances are reported, especially regarding septic arthritis. Translational research applications are described and explained in the final part, from the early histological studies and the first description of pathotype to more recent technologies involving -omics. Latest developments involving single-cell RNA sequence analysis have allowed the discovery of new cell subpopulations with remarkable roles in RA pathophysiology. These studies pave the ground for the discovery of new therapeutic targets and the implementation of personalized therapy in RA. Key Point•This review provides an overview of synovial biopsy techinques and applications especially in clinical and translational research.

2007 Award Winners: Distinguished Contributions to Education and Training.

2007 ◽  
Vol 62 (8) ◽  
pp. 824-849
Author(s):  
No authorship indicated
Keyword(s):  
Education And Training ◽  
And Training
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