Focal flow and neuronal activity in experimental cerebral ischemia

1977 ◽  
pp. 22-28 ◽  
Author(s):  
W.-D. Heiss ◽  
A. G. Waltz ◽  
T. Hayakawa
Keyword(s):  
Cerebral Ischemia ◽  
Neuronal Activity ◽  
Experimental Cerebral Ischemia

scholarly journals Experimental Cerebral Ischemia: Barbiturate Resistant Increase in Regional Glucose Utilization

1988 ◽  
Vol 8 (5) ◽  
pp. 763-766 ◽  
Author(s):  
Maiken Nedergaard ◽  
Nils Henrik Diemer
Keyword(s):  
Cerebral Ischemia ◽  
Middle Cerebral Artery ◽  
Neuronal Activity ◽  
Cerebral Artery ◽  
Glucose Utilization ◽  
Metabolic Response ◽  
Halothane Anesthesia ◽  
Cerebral Glucose Utilization ◽  
Ischemic Core ◽  
Experimental Cerebral Ischemia

During the first hours after experimental occlusion of the middle cerebral artery (MCA) cerebral glucose utilization increases in the tissue adjacent to ischemic focus, To test whether the increased glucose utilization was a consequence of increased neuronal activity, the effect of preocclusion pentobarbital administration was investigated, Rats in barbiturate-induced coma showed a metabolic response to MCA occlusion similar to those seen with light halothane anesthesia. This indicates that the enhanced glucose utilization adjacent to the ischemic core is not a result of increased neuronal activity.

Characterization of Gcf2/Lrrfip1 in experimental cerebral ischemia and its role as a modulator of Akt, mTOR and β-catenin signaling pathways

Neuroscience ◽  
2014 ◽  
Vol 268 ◽  
pp. 48-65 ◽  
Author(s):  
C. Gubern ◽  
S. Camós ◽  
O. Hurtado ◽  
R. Rodríguez ◽  
V.G. Romera ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
Signaling Pathways ◽  
Experimental Cerebral Ischemia
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