Functional Studies Performed with the Second International Workshop T Cell Panel of Monoclonal Antibodies

1986 ◽  
pp. 45-52 ◽  
Author(s):  
Dominique Charmot ◽  
Daniel Olive ◽  
Patrice Dubreuil ◽  
Marguerite Ragueneau ◽  
Claude Mawas
Keyword(s):  
Monoclonal Antibodies ◽  
T Cell ◽  
International Workshop ◽  
Functional Studies ◽  
Second International

Study on Human T Leukemia-Lymphoma Cell Lines by the Second International Workshop Monoclonal Antibodies of the T Cell Protocol

1986 ◽  
pp. 317-334 ◽  
Author(s):  
Jun Minowada ◽  
Mira Menon ◽  
Hans Guenter Drexler ◽  
Suzanne Gignac ◽  
Bishnupriya Misra ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
T Cell ◽  
Cell Lines ◽  
International Workshop ◽  
Lymphoma Cell ◽  
Second International

Studies of T Cell Proliferation Induced by Monoclonal Antibodies of the Second International Workshop

1986 ◽  
pp. 147-156
Author(s):  
Paul J. Martin ◽  
Jeffrey A. Ledbetter ◽  
Patrick G. Beatty ◽  
Edward A. Clark ◽  
John A. Hansen
Keyword(s):  
Cell Proliferation ◽  
Monoclonal Antibodies ◽  
T Cell ◽  
International Workshop ◽  
T Cell Proliferation ◽  
Second International

scholarly journals Cutaneous T cell lymphoma: characterization by monoclonal antibodies

Blood ◽  
1981 ◽  
Vol 57 (2) ◽  
pp. 261-266 ◽  
Author(s):  
PC Kung ◽  
CL Berger ◽  
G Goldstein ◽  
P LoGerfo ◽  
RL Edelson
Keyword(s):  
T Cells ◽  
Monoclonal Antibodies ◽  
T Cell ◽  
Cell Lymphoma ◽  
Cell Subset ◽  
T Cell Lymphoma ◽  
T Cell Subsets ◽  
Cutaneous T Cell Lymphoma ◽  
Functional Studies ◽  
Human T Cells

Abstract Monoclonal antibodies to human T cells permit the characterization of the surface phenotype of cutaneous T cell lymphoma (CTCL). The majority of CTCL cells are reactive with OKT1 and OKT3 monoclonals, which identify peripheral T cells and mature thymocytes. The neoplastic cells also react with OKT4, which recognizes the inducer T cell subset; they are, however, unreactive with OKT5 monoclonal, which identifies cytotoxic/suppressor T cell subsets. These data are in agreement with previous functional studies demonstrating that CTCL is a neoplasm of inducer (helper) T cells.

Second international workshop on monoclonal antibodies and breast cancer

1987 ◽  
Vol 10 (1) ◽  
pp. 55-63 ◽  
Author(s):  
Roberto L. Ceriani ◽  
Joseph Geradts ◽  
Jerry A. Peterson
Keyword(s):  
Breast Cancer ◽  
Monoclonal Antibodies ◽  
International Workshop ◽  
Second International

scholarly journals Cutaneous T cell lymphoma: characterization by monoclonal antibodies

Blood ◽  
1981 ◽  
Vol 57 (2) ◽  
pp. 261-266 ◽  
Author(s):  
PC Kung ◽  
CL Berger ◽  
G Goldstein ◽  
P LoGerfo ◽  
RL Edelson
Keyword(s):  
T Cells ◽  
Monoclonal Antibodies ◽  
T Cell ◽  
Cell Lymphoma ◽  
Cell Subset ◽  
T Cell Lymphoma ◽  
T Cell Subsets ◽  
Cutaneous T Cell Lymphoma ◽  
Functional Studies ◽  
Human T Cells

Monoclonal antibodies to human T cells permit the characterization of the surface phenotype of cutaneous T cell lymphoma (CTCL). The majority of CTCL cells are reactive with OKT1 and OKT3 monoclonals, which identify peripheral T cells and mature thymocytes. The neoplastic cells also react with OKT4, which recognizes the inducer T cell subset; they are, however, unreactive with OKT5 monoclonal, which identifies cytotoxic/suppressor T cell subsets. These data are in agreement with previous functional studies demonstrating that CTCL is a neoplasm of inducer (helper) T cells.

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