Classification of Endocrine Tumors by Histochemical Techniques

1994 ◽  
pp. 113-120
Author(s):  
Erik Wilander
Keyword(s):  
Endocrine Tumors

A Prognostic Clinicopathologic Classification of Pituitary Endocrine Tumors

2015 ◽  
Vol 44 (1) ◽  
pp. 11-18 ◽  
Author(s):  
Gérald Raverot ◽  
Alexandre Vasiljevic ◽  
Emmanuel Jouanneau ◽  
Jacqueline Trouillas
Keyword(s):  
Endocrine Tumors

scholarly journals A Rare Case of Mixed Ductal Neuroendocrine Tumor of the Pancreas

2021 ◽  
Vol 8 (2) ◽  
pp. C20-24
Author(s):  
Vidya Viswanathan ◽  
Harsh Kumar ◽  
Charusheela Gore ◽  
Shrikant Kurhade ◽  
Rumaanah Khan
Keyword(s):  
Neuroendocrine Tumour ◽  
Rare Condition ◽  
Collision Tumor ◽  
Definitive Diagnosis ◽  
Anatomical Site ◽  
Endocrine Tumors ◽  
Microscopic Features ◽  
To Come ◽  
Adenocarcinoma Component

Collision tumors are tumors that have at least two types of tumors in the same anatomical site with no area of mixing within the transition zone. In 2010 WHO classification of neuroendocrine tumors consists of an adenocarcinoma component and a neuroendocrine carcinoma component in which each of the components accounts for 30% of the tumor. Such tumors are defined as mixed adenoneuroendocrine carcinomas. Occurrence of exocrine and endocrine tumors of the pancreas is extremely rare. The aim of our study was to describe a case in a 60 years old male who was diagnosed with this rare tumor. Gross, microscopic features and immunohistochemistry were used to diagnose this rare condition. Immunohistochemistry markers such as synaptophysin, chromogranin, EMA and Pan CK were used to come to a definitive diagnosis. Synaptophysin and chromogranin were found to be positive in the neuroendocrine component. EMA and Pan CK were found to be positive in the ductal component. Hence a diagnosis of mixed ductal neuroendocrine tumour (collision tumor) was made.

Update on Pancreatic Endocrine Tumors

2006 ◽  
Vol 130 (7) ◽  
pp. 963-966 ◽  
Author(s):  
Wendy L. Frankel
Keyword(s):  
Mass Effect ◽  
Acinar Cell Carcinoma ◽  
Ductal Adenocarcinoma ◽  
Solid Pseudopapillary Tumor ◽  
Endocrine Tumors ◽  
Term Survival ◽  
Pancreatic Endocrine Tumors ◽  
Adjacent Structures

Abstract Endocrine tumors of the pancreas represent 1% to 2% of all pancreatic neoplasms. The tumors tend to have an indolent behavior, and long-term survival is common. There is no gender or age predilection. Patients can present with symptoms due to hormonal excess or a local mass effect or be asymptomatic. The tumors tend to be solid and well circumscribed. Typical microscopic findings include an organoid pattern of growth, with cells containing scant to moderate amounts of cytoplasm, and nuclei with dispersed chromatin and inconspicuous nucleoli. The morphologic spectrum of these tumors can be variable, and the differential diagnosis includes chronic pancreatitis with neuroendocrine hyperplasia, ductal adenocarcinoma, solid pseudopapillary tumor, acinar cell carcinoma, and pancreatoblastoma. The classification of these tumors remains controversial, and prognosis is difficult to predict, but important features include metastasis and invasion of adjacent structures. Resection remains the mainstay of surgical treatment. It is important to be aware that unusual morphologic variants of pancreatic endocrine tumors are common, and immunohistochemical stains can help avoid misdiagnosis.

scholarly journals Hypothalamic Endocrine Tumors: An Update

2019 ◽  
Vol 8 (10) ◽  
pp. 1741 ◽  
Author(s):  
Sylvia L. Asa ◽  
Ozgur Mete
Keyword(s):  
Structure Function ◽  
Endocrine Tumors ◽  
Hormonal Activity ◽  
Metabolic Homeostasis

The hypothalamus is the site of synthesis and secretion of a number of endocrine peptides that are involved in the regulation of hormonal activity of the pituitary and other endocrine targets. Tumors of the hypothalamus have been recognized to have both structural and functional effects including hormone hypersecretion. The classification of these tumors has advanced over the last few years, and biomarkers are now available to classify these tumors and provide accurate structure–function correlations. This review provides an overview of tumors in this region that is critical to metabolic homeostasis with a focus on advances in the diagnosis of gangliocytomas, neurocytomas, and pituicytomas that are unique to this region.

scholarly journals Single-cell approaches for molecular classification of endocrine tumors

2016 ◽  
Vol 28 (1) ◽  
pp. 43-49
Author(s):  
James Koh ◽  
Nancy L. Allbritton ◽  
Julie A. Sosa
Keyword(s):  
Single Cell ◽  
Molecular Classification ◽  
Endocrine Tumors

WHO 2010 classification of pancreatic endocrine tumors. Is the new always better than the old?

Pancreatology ◽  
2014 ◽  
Vol 14 (6) ◽  
pp. 539-541 ◽  
Author(s):  
Claudio Ricci ◽  
Riccardo Casadei ◽  
Giovanni Taffurelli ◽  
Marielda D'Ambra ◽  
Francesco Monari ◽  
...  
Keyword(s):  
Endocrine Tumors ◽  
Pancreatic Endocrine Tumors ◽  
Who 2010 Classification ◽  
Better Than

scholarly journals Mixed Adenoneuroendocrine Carcinoma of the Stomach

2015 ◽  
Vol 9 (2) ◽  
pp. 241-245 ◽  
Author(s):  
Ching-Ming Kwok
Keyword(s):  
Local Recurrence ◽  
Total Gastrectomy ◽  
Who Classification ◽  
Rare Condition ◽  
Gastric Tumor ◽  
Endocrine Tumors ◽  
Review Of The Literature ◽  
Carcinoma Of The Stomach ◽  
Mixed Adenoneuroendocrine Carcinoma

Mixed adenoneuroendocrine carcinoma is a rare condition comprising at least 30% of each component of exocrine and endocrine tumors. The denominations were defined in the 2000 WHO classification of endocrine tumors. We report an 83-year-old male with a polypoid gastric tumor in the gastric high body who received total gastrectomy and died 8 months after the diagnosis from local recurrence and distal metastases. A review of the literature for this infrequent condition is presented.

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