259 Human Brain Expressed Sequence Tags (ESTs): Chromosome Localization, Subregional Assignment, and Sequence Analysis

1994 ◽  
pp. 273-288 ◽  
Author(s):  
Donna R. Maglott ◽  
A. Scott Durkin ◽  
William C. Nierman
Keyword(s):  
Sequence Analysis ◽  
Human Brain ◽  
Expressed Sequence Tags ◽  
Chromosome Localization ◽  
Expressed Sequence

ANALYSIS OF EXPRESSED SEQUENCE TAGS FROM HUMAN BRAIN CDNAS

1993 ◽  
Author(s):  
Mark D. Adams ◽  
Anthony R. Kerlavage ◽  
Mark Dubnick ◽  
Ruben F. Moreno ◽  
Chris Fields ◽  
...  
Keyword(s):  
Human Brain ◽  
Expressed Sequence Tags ◽  
Expressed Sequence

Utility of Amborella trichopoda and Nuphar advena expressed sequence tags for comparative sequence analysis

Taxon ◽  
2008 ◽  
Vol 57 (4) ◽  
pp. 1110-383E ◽  
Author(s):  
Jill M. Duarte ◽  
Kerr P. Wall ◽  
Laura M. Zahn ◽  
Pamela S. Soltis ◽  
Douglas E. Soltis ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Expressed Sequence Tags ◽  
Comparative Sequence Analysis ◽  
Comparative Sequence ◽  
Expressed Sequence

Chromosome assignment of human brain expressed sequence tags (ESTs) by analyzing f luorescently labeled PCR products from hybrid cell panels

1994 ◽  
Vol 65 (1-2) ◽  
pp. 86-91 ◽  
Author(s):  
A.S. Durkin ◽  
W.C. Nierman ◽  
H. Zoghbi ◽  
C. Jones ◽  
C.A. Kozak ◽  
...  
Keyword(s):  
Human Brain ◽  
Expressed Sequence Tags ◽  
Hybrid Cell ◽  
Chromosome Assignment ◽  
Pcr Products ◽  
Expressed Sequence

3,400 new expressed sequence tags identify diversity of transcripts in human brain

1993 ◽  
Vol 4 (3) ◽  
pp. 256-267 ◽  
Author(s):  
Mark D. Adams ◽  
Anthony R. Kerlavage ◽  
Chris Fields ◽  
J. Craig Venter
Keyword(s):  
Human Brain ◽  
Expressed Sequence Tags ◽  
Expressed Sequence

Expressed sequence tags for the chicken genome from a normalized 10-day-old white leghorn whole-embryo cDNA library. 3. DNA sequence analysis of genetic variation in commercial chicken populations

Genome ◽  
2002 ◽  
Vol 45 (2) ◽  
pp. 261-267 ◽  
Author(s):  
E J Smith ◽  
L Shi ◽  
G Smith
Keyword(s):  
Sequence Analysis ◽  
Dna Sequence ◽  
Dna Sequences ◽  
Expressed Sequence Tags ◽  
Chicken Genome ◽  
Dna Sequence Analysis ◽  
Genetic Maps ◽  
Commercial Chicken ◽  
Genomic Regions ◽  
Expressed Sequence

Single nucleotide polymorphisms (SNPs) have emerged as a major class of DNA markers with the advantage of permitting the development of high-density genetic maps adequate for quantitative trait loci (QTL) identification by linkage-disequilibrium analysis. Here we describe results of a relatively high-depth survey of chicken broiler and layer populations for SNPs in targeted genomic regions of chicken expressed sequence tag (EST) sites. The sequences scanned, representing the composite sequence of 12 amplified fragments for a total of 6489 bp, were randomly distributed, occurring on six different chromosomes or linkage groups in the chicken genome. Although one of the genomic DNA sequences did not match the reference cDNA sequence, another contained an intron that separated two putative exons. The number of SNPs observed within each of the 12 EST-targeted genomic regions ranged from 0 to 10 for a total of 44 and a frequency of 0.7%. About 70% of the polymorphisms were shared between layer and broiler populations. The average heterozygosity within the populations ranged from 0.15 to 0.48, with the layer populations showing the higher heterozygosity. SNPs and oligonucleotides described will provide a resource for genetic analysis in commercial chicken populations. The data appear to indicate that the relative frequency of SNPs in the targeted regions scanned is higher than the frequency reported for any of the other regions scanned to date in other eukaryotic genomes. Additionally, the results suggest that the use of DNA pools may offer an efficient approach to SNP detection in chickens, as has been shown in other vertebrates.Key words: DNA sequence analysis, SNPs, expressed sequence tags, chicken.

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