Anticancer Quinones and Quinolines: Mode of Action Via Electron Transfer and Oxidative Stress

1988 ◽  
pp. 295-307 ◽  
Author(s):  
Peter Kovacic ◽  
James R. Ames ◽  
James W. Grogan ◽  
Banasri Hazra ◽  
Michael D. Ryan
Keyword(s):  
Oxidative Stress ◽  
Electron Transfer ◽  
Mode Of Action ◽  
And Oxidative Stress

scholarly journals Unifying Mechanism for Nutrients as Anticancer Agents: Electron Transfer, Reactive Oxygen Species and Oxidative Stress

2017 ◽  
Vol 9 (8) ◽  
pp. 66 ◽  
Author(s):  
Peter Kovacic ◽  
Ratnasamy Somanathan
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Electron Transfer ◽  
Anticancer Agents ◽  
Mode Of Action ◽  
Recent Article ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Bactericidal Action ◽  
And Oxidative Stress

A recent article deals with various nutrients in relation to bactericidal action. The present article focuses on a unifying mode of action for the nutrients, namely, resveratrol, epigallocatechin, polyene-ß-carotene, polyene lycopene, piperine, curcumin, genistein, luteolin, sulforaphane and pomegranate extract. The mechanism is based on electron transfer, reactive oxygen species and oxidative stress, which comprises an extension of earlier reports involving agents. Most of the compounds are precursors of electron transfer quinones, whereas others fit into the polyene category. The nutrients are better known as antioxidants. The dichotomy is addressed.

scholarly journals Role of membrane disturbance and oxidative stress in the mode of action underlying the toxicity of differently charged polystyrene nanoparticles

RSC Advances ◽  
2014 ◽  
Vol 4 (37) ◽  
pp. 19321-19330 ◽  
Author(s):  
Sourav Bhattacharjee ◽  
Dmitry Ershov ◽  
Mohammed A. Islam ◽  
Angela M. Kämpfer ◽  
Katarzyna A. Maslowska ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mode Of Action ◽  
Cell Membranes ◽  
Polystyrene Nanoparticles ◽  
And Oxidative Stress ◽  
Positively Charged

Positively charged polystyrene nanoparticles show are cytotoxic, induce oxidative stress and create holes/pores in cell membranes.

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