Cohesive Properties of Solids

Author(s):  
Jean-Louis Calais
Keyword(s):  
2013 ◽  
Vol 88 (3) ◽  
pp. 486-500 ◽  
Author(s):  
Zhe Wan ◽  
Pamela J. B. Brown ◽  
Ellen N. Elliott ◽  
Yves V. Brun

1998 ◽  
Vol 58 (8) ◽  
pp. 4345-4351 ◽  
Author(s):  
Anna Delin ◽  
Lars Fast ◽  
Börje Johansson ◽  
Olle Eriksson ◽  
J. M. Wills

1990 ◽  
Vol 42 (15) ◽  
pp. 9357-9364 ◽  
Author(s):  
X. J. Kong ◽  
C. T. Chan ◽  
K. M. Ho ◽  
Y. Y. Ye

2017 ◽  
Vol 46 (7) ◽  
pp. 4485-4496 ◽  
Author(s):  
S. B. Ramos ◽  
N. V. González Lemus ◽  
C. E. Deluque Toro ◽  
G. F. Cabeza ◽  
A. Fernández Guillermet

2010 ◽  
Vol 46 (3) ◽  
pp. 531-537
Author(s):  
Michael Ayodele Odeniyi ◽  
Collins Chidi Onyenaka ◽  
Oludele Adelanwa Itiola

A study was conducted on the packing and cohesive properties of chloroquine phosphate in binary mixtures with lactose and dicalcium phosphate powders. The maximum volume reduction due to packing as expressed by the Kawakita constant, a, and the angle of internal flow, θ, were the assessment parameters. The individual powders were characterized for their particle size and shape using an optical microscope. Binary mixtures of various proportions of chloroquine phosphate with lactose and dicalcium phosphate powders were prepared. The bulk and tapped densities, angles of repose and internal flow, as well as compressibility index of the materials were determined using appropriate parameters. The calculated and determined values of maximum volume reduction for the binary mixtures were found to differ significantly (P< 0.05), with the Kawakita plot being more reliable in determining the packing properties. Diluent type was found to influence the flow properties of the mixtures, with dicalcium phosphate giving predictable results while mixtures containing lactose were anomalous with respect to flow. The characterization of the packing and cohesive properties of the binary mixtures of chloroquine with lactose and dicalcium phosphate would be useful in the production of powders, tablets, capsules and other drug delivery systems containing these powders with desirable and predictable flow properties.


1983 ◽  
Vol 44 (12) ◽  
pp. 1355-1363 ◽  
Author(s):  
G. Allan ◽  
M. Lannoo
Keyword(s):  

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