Experimental and Epidemiologic Applications to Cancer Risk Assessment of Complex Mixtures

Author(s):  
Marja Sorsa ◽  
Harri Vainio ◽  
Anthony J. McMichael
1985 ◽  
Vol 1 (4) ◽  
pp. 193-203 ◽  
Author(s):  
Joellen Lewtas

A comparative potency method for cancer risk assessment has been developed based on a constant relative potency hypothesis. This method was developed and tested using data from a battery of short-term mutagenesis bioassays, animal tumorigenicity data and human lung cancer risk estimations. This data base was developed for a series of complex mixtures including emissions from coke ovens, roofing tar pots, cigarette smoke and automotive engines. The series of automobiles used in this study included both diesel- and gasoline-powered vehicles. The assumptions inherent in this method are discussed, together with the methods and data base used to test these assumptions.


Food Control ◽  
2021 ◽  
Vol 124 ◽  
pp. 107867
Author(s):  
Sunghyeon Jung ◽  
Seungmin Kim ◽  
Inhwan Kim ◽  
Myung-Sub Chung ◽  
BoKyung Moon ◽  
...  

Author(s):  
Stojan Trajanovski ◽  
Dimitrios Mavroeidis ◽  
Christine Leon Swisher ◽  
Binyam Gebrekidan Gebre ◽  
Bastiaan S. Veeling ◽  
...  

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