Mnemonic Function of the Hippocampus: Correspondence between Animals and Humans

Author(s):  
Raymond P. Kesner
Keyword(s):  
2017 ◽  
Vol 147 (12) ◽  
pp. 2297-2308 ◽  
Author(s):  
Michael J Wenger ◽  
Laura E Murray-Kolb ◽  
Julie EH Nevins ◽  
Sudha Venkatramanan ◽  
Gregory A Reinhart ◽  
...  

Abstract Background: Iron deficiency and iron deficiency anemia have been shown to have negative effects on aspects of perception, attention, and memory. Objective: The purpose of this investigation was to assess the extent to which increases in dietary iron consumption are related to improvements in behavioral measures of perceptual, attentional, and mnemonic function. Methods: Women were selected from a randomized, double-blind, controlled food-fortification trial involving ad libitum consumption of either a double-fortified salt (DFS) containing 47 mg potassium iodate/kg and 3.3 mg microencapsulated ferrous fumarate/g (1.1 mg elemental Fe/g) or a control iodized salt. Participants' blood iron status (primary outcomes) and cognitive functioning (secondary outcomes) were assessed at baseline and after 10 mo at endline. The study was performed on a tea plantation in the Darjeeling district of India. Participants (n = 126; 66% iron deficient and 49% anemic at baseline) were otherwise healthy women of reproductive age, 18–55 y. Results: Significant improvements were documented for iron status and for perceptual, attentional, and mnemonic function in the DFS group (percentage of variance accounted for: 16.5%) compared with the control group. In addition, the amount of change in perceptual and cognitive performance was significantly (P < 0.05) related to the amount of change in blood iron markers (mean percentage of variance accounted for: 16.0%) and baseline concentrations of blood iron markers (mean percentage of variance accounted for: 25.0%). Overall, there was evidence that the strongest effects of change in iron status were obtained for perceptual and low-level attentional function. Conclusion: DFS produced measurable and significant improvements in the perceptual, attentional, and mnemonic performance of Indian female tea pickers of reproductive age. This trial was registered at clinicaltrials.gov as NCT01032005.


2021 ◽  
Vol 89 (9) ◽  
pp. S210
Author(s):  
James Bauer ◽  
Sarah Rader ◽  
Max Joffe ◽  
Wooseok Kwon ◽  
Juliana Quay ◽  
...  

2019 ◽  
pp. 175069801988872
Author(s):  
Robb Conrad Lauzon

In this article, I argue that the meaning of memorial space can be better understood by turning our focus to the ambient characteristics of these spaces. Ambience is used here to refer to the environmental features that exist at the periphery of our attention. Here, I offer advice from ancient teachers of the art of memory that prescribes spaces with particular environmental qualities as evidence of the important role that these spaces serve in the storage and recollection of memories. Advice such as practice in solitude in dim lit spaces—or well lit, according to the teacher—highlights the importance that these ancient teachers placed on ambience for the proper storage of memories. We also know that these architectural mnemonic features were also “turned outward” to convey meaning. Instead of the traditional semiotic approach to architectural criticism that looks at commemorative symbolism, this article follows an approach that interrogates architecture’s mnemonic function. An analysis of the ambient features emphasized in Ottawa’s urban planning documents reveals that this is an important yet often overlooked aspect of urban spaces by those who study memorials. The Todd Plan, The Holt Report, and The Gréber Plan serve as a foundation for understanding the character of Ottawa’s space. Other more recent urban planning documents from the National Capital Commission are brought in to demonstrate how the role of ambience is afforded even greater prominence than it already was. Reconsidering the different types of spaces (natural and open space) and the role of sensation as uniquely ambient features of space open up new possibilities for examining the memories that these characteristics invoke in audiences. By unpacking the meaning of memorial space, through a mnemonic lens we are able to more thoughtfully engage with the reception of these spaces by visitors.


2005 ◽  
Vol 39 (1) ◽  
pp. 4-7
Author(s):  
N. I. Andreeva ◽  
V. V. Asnina ◽  
M. A. Kalinkina ◽  
V. A. Parshin ◽  
S. D. Yuzhakov ◽  
...  

2019 ◽  
pp. 91-128
Author(s):  
Vered Lev Kenaan

An analysis in which the Homeric digression intersects with Freud’s notion of regression leads into a comprehensive reading of the Homeric episode of the foot washing of the Odyssey, Book 19. The chapter concentrates on the mnemonic function of the scar in the Homeric epic and Sophocles’ tragedy. The chapter considers the significance of Oedipus’ childhood memories in shaping the tragic plot of Oedipus Rex as a tragedy of recollection. Oedipus’ and Odysseus’ scars bring home something that has collapsed into forgetfulness. The chapter discusses the significance of ancient and Freudian figures and images of scars as junctions of forgetting and remembering, and shows how ancient narratives of memory (Odysseus) and forgetfulness (Oedipus) can inform our understanding of Freud’s notion of the dream navel.


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