Digoxigenin Labeled Probes and their Use in the Laboratory Diagnosis of Virus Infections

1994 ◽  
pp. 101-112 ◽  
Author(s):  
Pirkko Heino ◽  
Veijo Hukkanen ◽  
Pertti P. Arstila
2019 ◽  
Vol 57 (5) ◽  
Author(s):  
William J. Muller ◽  
Xiaotian Zheng

ABSTRACT Herpes simplex virus (HSV) is a common and often benign infection in humans; although it less commonly affects newborns, infection in this age group can be devastating. Newborns often present with nonspecific clinical findings, making timely and accurate diagnosis of infection critical. A wide variety of tests are available for detecting herpes simplex virus infection, but only a subset are useful and validated in the newborn population. The current review summarizes available diagnostic testing for neonatal disease, including discussing limitations, unmet needs, and emerging data on molecular testing methods.


2021 ◽  
Vol 6 (3) ◽  
pp. 11-15
Author(s):  
Utibe-Abasi O. Alfred ◽  
Euphoria C. Akwiwu ◽  
Valerie E. Ugochi ◽  
Josephine O. Akpotuzor

Despite emerging infections and diseases that are transmissible through poor gynaecology/ obstetrics care, preference for traditional birth attendants over conventional caregivers still exist. Laboratory diagnosis remains essential for detection of new cases as well as overall management of infected persons. Pregnant women accessing care at traditional birth homes constitute a vulnerable group since laboratory testing for hepatitis is lacking at the centers, hence the present study. This study employed a descriptive cross-sectional study design. The study participants were pregnant women accessing care at traditional birth homes in Uyo, Akwa Ibom State of Nigeria. The subjects were each screened for the presence of antibodies to HBV and HCV using immunochromatographic methods. Data processing was carried out using SPSS version 22.0. Results are presented as numbers and frequencies expressed as percentages. Socio-economic variables including education and income were seen to be disproportionally distributed among the pregnant women accessing care at traditional birth homes. Five (5) out of 88 enrolled pregnant women were reactive to either of both viral hepatitis screened. The prevalence of HBV (4.5%) was higher than that of HCV (1.1%). Six out of the seven (85.7%) centers informed the attendees of the need to undertake laboratory screening for transmissible infections. However, none of the centers made it mandatory for laboratory test results to be obtained. One center out of seven (14.3%) ensured that sharps used during child delivery were not shared. This study observed the prevalence of hepatitis B and C virus infections among pregnant women attending traditional birth homes in Uyo, Nigeria to be 4.5% and 1.1% respectively.


2014 ◽  
Vol 9 (8) ◽  
pp. 721-731 ◽  
Author(s):  
Feinan Fan ◽  
Stephen Day ◽  
Xuedong Lu ◽  
Yi-Wei Tang

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