Antioxidant Therapeutic Strategies in CNS Disorders

1997 ◽  
pp. 325-339 ◽  
Author(s):  
Edward D. Hall
Keyword(s):  
Therapeutic Strategies ◽  
Cns Disorders

scholarly journals Sugar glues for broken neurons

2013 ◽  
Vol 4 (3) ◽  
pp. 233-257 ◽  
Author(s):  
Vimal P. Swarup ◽  
Caitlin P. Mencio ◽  
Vladimir Hlady ◽  
Balagurunathan Kuberan
Keyword(s):  
Therapeutic Strategies ◽  
Matrix Proteins ◽  
Cell Surface Molecules ◽  
Cns Development ◽  
Cns Disorders ◽  
Surface Molecules ◽  
The Past ◽  
The Central Nervous System ◽  
Neurological Processes

AbstractProteoglycans (PGs) regulate diverse functions in the central nervous system (CNS) by interacting with a number of growth factors, matrix proteins, and cell surface molecules. Heparan sulfate (HS) and chondroitin sulfate (CS) are two major glycosaminoglycans present in the PGs of the CNS. The functionality of these PGs is to a large extent dictated by the fine sulfation patterns present on their glycosaminoglycan (GAG) chains. In the past 15 years, there has been a significant expansion in our knowledge on the role of HS and CS chains in various neurological processes, such as neuronal growth, regeneration, plasticity, and pathfinding. However, defining the relation between distinct sulfation patterns of the GAGs and their functionality has thus far been difficult. With the emergence of novel tools for the synthesis of defined GAG structures, and techniques for their characterization, we are now in a better position to explore the structure-function relation of GAGs in the context of their sulfation patterns. In this review, we discuss the importance of GAGs on CNS development, injury, and disorders with an emphasis on their sulfation patterns. Finally, we outline several GAG-based therapeutic strategies to exploit GAG chains for ameliorating various CNS disorders.

Pain: The Ubiquitous Influence Across CNS Disorders and Injuries

2008 ◽  
Author(s):  
Missy Coblentz ◽  
Kim Bond ◽  
Pennie S. Seibert ◽  
Carin M. Patterson ◽  
Caitlin C. Otto ◽  
...  
Keyword(s):  
Cns Disorders

Therapeutic strategies and techniques in early cognitive-behavioral therapy.

Psychotherapy ◽  
2019 ◽  
Vol 56 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Brittany R. King ◽  
James F. Boswell
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Behavioral Therapy ◽  
Therapeutic Strategies ◽  
Cognitive Behavioral

A Comprehensive Review on Diagnostic and Therapeutic Strategies for the Management of Pancreatic Cancer

2020 ◽  
Author(s):  
Vibha Sinha ◽  
Sapnita Shinde ◽  
Saurabh Ssaxena ◽  
Suresh Thakur ◽  
Tamanna Walia ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Strategies ◽  
Comprehensive Review
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