Serum Cholinesterase in Diabetes

1994 ◽  
pp. 27-33
Author(s):  
K. M. Kutty
Keyword(s):  
Serum Cholinesterase

The Effects of Oral Pyridostigmine on Serum Cholinesterase Activity in Macaca mulatta

1987 ◽  
Author(s):  
Dennis W. Blick ◽  
Michael R. Murphy ◽  
Duane P. Dawson ◽  
G. C. Brown
Keyword(s):  
Macaca Mulatta ◽  
Cholinesterase Activity ◽  
Serum Cholinesterase ◽  
Serum Cholinesterase Activity

scholarly journals Oxime Reactivation of Diethylphosphoryl Human Serum Cholinesterase

1967 ◽  
Vol 242 (11) ◽  
pp. 2683-2687
Author(s):  
E.I.C. Wang ◽  
P.E. Braid
Keyword(s):  
Human Serum ◽  
Serum Cholinesterase

scholarly journals Interchain disulfide bonds and subunit organization in human serum cholinesterase.

1979 ◽  
Vol 254 (17) ◽  
pp. 8324-8330
Author(s):  
O. Lockridge ◽  
H.W. Eckerson ◽  
B.N. La Du
Keyword(s):  
Human Serum ◽  
Disulfide Bonds ◽  
Serum Cholinesterase ◽  
Subunit Organization

scholarly journals Cholinesterase activity in serum during general anesthesia in patients with or without vascular disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yitzhak Brzezinski-Sinai ◽  
Ester Zwang ◽  
Elena Plotnikova ◽  
Ester Halizov ◽  
Itzhak Shapira ◽  
...  
Keyword(s):  
Vascular Surgery ◽  
General Anesthesia ◽  
Vascular Disease ◽  
Cholinesterase Activity ◽  
Serum Cholinesterase ◽  
Hemodynamic Support ◽  
System A ◽  
Lower Baseline ◽  
Increased Risk ◽  
A Prospective Study

AbstractMaintaining hemodynamic stability during the induction and maintenance of anesthesia is one of the challenges of the anesthesiologist. Patients with vascular disease are at increased risk of instability due to imbalance between the sympathetic and parasympathetic parts of the autonomic nervous system, a balance accessible by serum cholinesterase activity. We aim to characterize the dynamics of cholinesterase activity in patients undergoing general anesthesia (GA) and surgery. This was a prospective study of 57 patients undergoing ambulatory or vascular surgery under GA. Cholinesterase activity was measured before the induction of anesthesia, after 15 min and at the end of surgery by calculating the capacity of serum acetylcholinesterase (AChE) and butyrylcholinesterase to hydrolyze AcetylThioCholine. Data on atherosclerotic disease, anesthesia management were analyzed. Both AChE and total cholinergic status (CS) decreased significantly after GA induction at 15 min and even more so by the end of surgery. Vascular surgery patients had lower baseline cholinesterase activity compared to ambulatory surgery patients. Patients requiring intraoperative administration of phenylephrine for hemodynamic support (21.1%) had a significantly lower level of AChE and CS compared to untreated patients. Our findings serve as a mirror to the sympathetic/parasympathetic imbalance during GA, with a marked decrease in the parasympathetic tone. The data of a subgroup analysis show a correlation between low cholinesterase activity and an increase in the need for hemodynamic support.

Colorimetric Method for the Determination of Serum Cholinesterase*

1952 ◽  
Vol 22 (11_ts) ◽  
pp. 1126-1133 ◽  
Author(s):  
J. de la Huerga ◽  
Charlotte Yesinick ◽  
Hans Popper
Keyword(s):  
Colorimetric Method ◽  
Serum Cholinesterase

scholarly journals Purification of Horse Serum Cholinesterase by Preparative Polyacrylamide Gel Electrophoresis

1972 ◽  
Vol 247 (2) ◽  
pp. 566-571
Author(s):  
A. Russell Main ◽  
Emel Tarkan ◽  
John L. Aull ◽  
William G. Soucie
Keyword(s):  
Gel Electrophoresis ◽  
Horse Serum ◽  
Polyacrylamide Gel Electrophoresis ◽  
Polyacrylamide Gel ◽  
Serum Cholinesterase

CHEl UF Serum Cholinesterase Phenotype in Whites and Non-Whites from Southern Brazil as Determined by a New Method

1991 ◽  
Vol 41 (2) ◽  
pp. 103-106 ◽  
Author(s):  
Vânia M. Alcântara ◽  
Eleidi A. Chautard-Freire-Maia ◽  
L. Culpi
Keyword(s):  
New Method ◽  
Serum Cholinesterase ◽  
Southern Brazil

Serum Cholinesterase Variants: Examination of Several Differential Inhibitors, Salts, and Buffers Used to Measure Enzyme Activity

1971 ◽  
Vol 17 (3) ◽  
pp. 183-191 ◽  
Author(s):  
Philip J Garry
Keyword(s):  
Enzyme Activity ◽  
Sodium Fluoride ◽  
Phosphate Buffer ◽  
Divalent Cations ◽  
Kinetic Studies ◽  
Competitive Inhibitor ◽  
Serum Cholinesterase ◽  
Low Concentrations

Abstract Dibucaine, used as a differential inhibitor with acetyl-, propionyl-, and butyrylthiocholine as substrate, clearly identified the "usual" and "atypical" serum cholinesterases. Succinylcholine was also used successfully as a differential inhibitor with butyrylthiocholine as substrate. Sodium fluoride, used as a differential inhibitor, gave conflicting results, depending on whether Tris or phosphate buffer was used in the assay. Mono- and divalent cations (NaCl, KCl, MgCl2, CaCl2, and BaCl2) activated the "usual" and inhibited the "atypical" enzyme at low concentrations. The "usual" enzyme had the same activity in 0.05 mol of Tris or phosphate buffer per liter, while the heterozygous and "atypical" enzymes showed 12 and 42% inhibition, respectively, when assayed in the phosphate buffer. Kinetic studies showed the phosphate acted as a competitive inhibitor of "atypical" enzyme. Km values, determined for "usual" and "atypical" enzymes, were 0.057 and 0.226 mmol/liter, respectively, with butyrylthiocholine as substrate.

Serum cholinesterase and sex glands

1949 ◽  
Vol 57 (4) ◽  
pp. 815
Author(s):  
Clair E. Folsome
Keyword(s):  
Serum Cholinesterase
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