Cloning and Characterisation of a Mosquito Acetylcholinesterase Gene

1990 ◽  
pp. 57-65 ◽  
Author(s):  
Colin A. Malcolm ◽  
Lucinda M. C. Hall
Keyword(s):  
Acetylcholinesterase Gene

Chronic enhancement of neuromuscular activity increases acetylcholinesterase gene expression in skeletal muscle

1995 ◽  
Vol 269 (4) ◽  
pp. C856-C862 ◽  
Author(s):  
H. Sveistrup ◽  
R. Y. Chan ◽  
B. J. Jasmin
Keyword(s):  
Ache Activity ◽  
Wheel Running ◽  
Compensatory Hypertrophy ◽  
Molecular Forms ◽  
Plantaris Muscle ◽  
Neuromuscular Activation ◽  
Neuromuscular Activity ◽  
Acetylcholinesterase Gene ◽  
Voluntary Wheel

We determined levels of mRNA encoding acetylcholinesterase (AChE) in muscles of rats subjected to chronic enhancement of neuromuscular activation. After 8 wk of voluntary wheel running, extensor digitorum longus (EDL) muscles displayed a 72% increase in total AChE activity as a result of a selective threefold increase in the G4 content. Soleus muscles, on the other hand, exhibited a 30% decrease in A12 while displaying a small (33%) increase in total AChE activity. These enzymatic adaptations were paralleled by increases in the levels of AChE mRNAs in both EDL (32%; P < 0.03) and soleus (42%; P < 0.02) muscles. In addition, compensatory hypertrophy of the plantaris muscle increased total AChE activity by 75%. This change was reflected by an elevation in all AChE molecular forms with A12 (89%) and A8 (179%) showing the most prominent increases. Similar to exercise-trained muscles, hypertrophied plantaris muscles displayed an increase in AChE transcripts (25%; P < 0.04). These results indicate that increases in neuromuscular activity modulate expression of the AChE gene in vivo and suggest the involvement of pretranslational regulatory mechanisms in the adaptive response of AChE to enhanced neuromuscular activation.

Acetylcholinesterase gene polymorphism and recurrent pregnancy loss

2009 ◽  
Vol 106 (1) ◽  
pp. 68-69
Author(s):  
Farah Parveen ◽  
Gaurav Tripathi ◽  
Bhanumati Singh ◽  
Rehan M. Faridi ◽  
Suraksha Agrawal
Keyword(s):  
Gene Polymorphism ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Acetylcholinesterase Gene

Expression of the Acetylcholinesterase Gene in Skeletal Muscle Fibers

1998 ◽  
pp. 119-120
Author(s):  
Roxanne Y. Y. Chan ◽  
Céline Boudreau-Larivière ◽  
Fawzi A. Mankal ◽  
Lindsay Angus ◽  
Andrea M. Krupa ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibers ◽  
Skeletal Muscle Fibers ◽  
Acetylcholinesterase Gene

scholarly journals A novel acetylcholinesterase gene in mosquitoes codes for the insecticide target and is non–homologous to the ace gene Drosophila

2002 ◽  
Vol 269 (1504) ◽  
pp. 2007-2016 ◽  
Author(s):  
Mylène Weill ◽  
Philippe Fort ◽  
Arnaud Berthomieu ◽  
Marie Pierre Dubois ◽  
Nicole Pasteur ◽  
...  
Keyword(s):  
Ace Gene ◽  
Acetylcholinesterase Gene
Sign in / Sign up

Export Citation Format

Share Document