Phased Genome Sequencing Through Chromosome Sorting

2017 ◽  
pp. 171-188 ◽  
Author(s):  
Xi Chen ◽  
Hong Yang ◽  
Wing Hung Wong
Keyword(s):  
Genome Sequencing ◽  
Chromosome Sorting

scholarly journals Completely phased genome sequencing through chromosome sorting

2010 ◽  
Vol 108 (1) ◽  
pp. 12-17 ◽  
Author(s):  
Hong Yang ◽  
Xi Chen ◽  
Wing Hung Wong
Keyword(s):  
Personalized Medicine ◽  
Long Range ◽  
Genome Sequencing ◽  
Genetic Information ◽  
Haploid Genome ◽  
Genomic Sequences ◽  
Phase Information ◽  
Genome Sequences ◽  
Chromosome Sorting ◽  
Entire Chromosome

The two haploid genome sequences that a person inherits from the two parents represent the most fundamentally useful type of genetic information for the study of heritable diseases and the development of personalized medicine. Because of the difficulty in obtaining long-range phase information, current sequencing methods are unable to provide this information. Here, we introduce and show feasibility of a scalable approach capable of generating genomic sequences completely phased across the entire chromosome.

scholarly journals Whole genome sequencing of a natural recombinant Toxoplasma gondii strain reveals chromosome sorting and local allelic variants

2009 ◽  
Vol 10 (5) ◽  
pp. R53 ◽  
Author(s):  
Irene Bontell ◽  
Neil Hall ◽  
Kevin E Ashelford ◽  
JP Dubey ◽  
Jon P Boyle ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Whole Genome ◽  
Chromosome Sorting ◽  
Allelic Variants

Chromosome sorting and its applications in common wheat (Triticum aestivum) genome sequencing

2010 ◽  
Vol 55 (15) ◽  
pp. 1463-1468 ◽  
Author(s):  
SuoWei Wu ◽  
Yang Xiao ◽  
Xu Zheng ◽  
YingFan Cai ◽  
Jaroslav Doležel ◽  
...  
Keyword(s):  
Triticum Aestivum ◽  
Common Wheat ◽  
Genome Sequencing ◽  
Chromosome Sorting

Genome Sequencing Set to Hunt for Alzheimer's Clues

2012 ◽  
Vol 45 (13) ◽  
pp. 36
Author(s):  
MICHELE G. SULLIVAN
Keyword(s):  
Genome Sequencing

Utility of Whole Genome Sequencing in diagnosing complex disorders: lesson from renal tubular disorders

2018 ◽  
Author(s):  
Mark Stevenson ◽  
Alistair T Pagnamenta ◽  
Heather G Mack ◽  
Judith A Savige ◽  
Kate E Lines ◽  
...  
Keyword(s):  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Whole Genome ◽  
Complex Disorders ◽  
Tubular Disorders ◽  
Renal Tubular Disorders ◽  
Renal Tubular
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